Transcriptomic profiling of the Saccharomyces cerevisiae response to quinine reveals a glucose limitation response attributable to drug-induced inhibition of glucose uptake

Antimicrobial Agents and Chemotherapy

Volumn 53, Issue 12, 2009, Pages 5213-5223

  Dos Santos, Sandra C ^a   Tenreiro, Sandra ^a   Palma, Margarida ^a   Becker, Jorg ^b   Sá Correia, Isabel ^a  

^a INSTITUTO SUPERIOR TÉCNICO   (Portugal)

^b INSTITUTO GULBENKIAN DE CIÊNCIA   (Portugal)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; GLUCOSE TRANSPORTER; GLUCOSE TRANSPORTER 1; GLUCOSE TRANSPORTER 5; GLUCOSE TRANSPORTER 8; GLUCOSER TRANSPORTER 10; QUININE; SNF3 PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR ADR1; TRANSCRIPTION FACTOR CAT8; TRANSCRIPTION FACTOR MAL33; TRANSCRIPTION FACTOR MTH1; UNCLASSIFIED DRUG;

ANTIMALARIAL DRUG RESISTANCE; ARTICLE; CELL GROWTH; CELL MEMBRANE; COMPETITIVE INHIBITION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MECHANISM; DRUG TRANSPORT; DRUG UPTAKE; EUKARYOTE; FUNGAL CELL; FUNGAL STRAIN; FUNGUS MUTANT; GENE ACTIVATION; GENE DELETION; GENE EXPRESSION PROFILING; GLUCOSE TRANSPORT; GROWTH INHIBITION; IC 50; MOLECULAR MODEL; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE; TRANSCRIPTOMICS;

BIOLOGICAL TRANSPORT; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, FUNGAL; GLUCOSE; MODELS, BIOLOGICAL; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; QUININE; SACCHAROMYCES CEREVISIAE;

EID: 71249094263     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.00794-09     Document Type: Article

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