Long-term benefit of intracardiac delivery of autologous granulocytecolony-stimulating factor-mobilized blood CD341 cells containing cardiac progenitors on regional heart structure and function after myocardial infarct

Cytotherapy

Volumn 11, Issue 8, 2009, Pages 1002-1015

  Pasquet, Stphanie ^a   Sovalat, Hanna ^a   Hnon, Philippe ^a,b,c   Bischoff, Nicolas ^b   Arkam, Yazid ^b   Ojeda Uribe, Mario ^b   Bouar, Ronan Le ^b   Rimelen, Valérie ^b   Brink, Ingo ^d   Dallemand, Robert ^b   Monassier, Jean Pierre ^b  

^a Institut de Recherche en Hmatologie et Transplantation (IRHT)   (France)

^b Hpital E Muller ^*  (France)

^c UNIVERSITÉ DE HAUTE ALSACE   (France)

^d UNIVERSITY OF FREIBURG   (Germany)

Author keywords

Acute myocardial infarct; Cardiomyocyte; Cell therapy; Stem cells.

Indexed keywords

GRANULOCYTE COLONY STIMULATING FACTOR; RECOMBINANT GRANULOCYTE COLONY STIMULATING FACTOR;

ADULT; AGED; ARTICLE; CD4+ T LYMPHOCYTE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED STUDY; FLOW CYTOMETRY; HEART FUNCTION; HEART INFARCTION; HEART LEFT VENTRICLE FUNCTION; HEART MUSCLE CELL; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; LEUKAPHERESIS; PRIORITY JOURNAL; REGENERATION; REVASCULARIZATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STEM CELL;

EID: 71149100027     PISSN: 14653249     EISSN: 14772566     Source Type: Journal    
DOI: 10.3109/14653240903164963     Document Type: Article

References (40)

1. Orlic D, Kajstura J, C himenti S, J akoniuk I, A nderson S, Li B, et al. Bone marrow cells regenerate infarcted myocardium. Nature 2001; 410: 701-705
2. Assmus B, H onold J, S chachinger V, B ritten M, Fischer-Rasokat U, Lehmann R, et al. Transcoronary transplantation of progenitor cells after myocardial infarction. New Engl J Med 2006; 355: 1222-1232 (Pubitemid 44427446)
3. Janssens S, D ubois C, B ogaert J, T eheunissen K, D eroose C, Desmet W, et al. Autologous bone marrow-derived stem-cell transfer in patients with ST-segment elevation myocardial infarction: double-blind, randomised controlled trial. Lancet 2006; 367: 113-121
4. Kuethe F, Richartz BM, S ayer HG, K asper C, W erner G, Hoffken K, et al. Lack of regeneration of myocardium bY autologous intracoronary mononuclear bone marrow cell transplantation in humans with large anterior myocardial infarctions. Int J Cardiol 2004; 97: 123-127
5. Lunde K, Solheim S, AakhusS, Arnesen H, A bdelnoor M, Egeland T, et al. Intracoronary injection of mononuclear bone marrow cells in acute myocardial infarction. New Engl J Med 2006; 355: 1199-1209
6. Patel A, G effner L, Vina RF, Saslavsky J, Urschel HJ, Kormos R, et al. Surgical treatment for congestive heart failure with autologous adult stem cell transplantation: a prospective randomized study. J Thorac Cardiovasc Surg 2005; 130: 1631-1638
7. Perin E, Dohmann H, Borojevic R, S ilva S, Sousa A, Silva G, et al. Improved exercise capacity and ischemia 6 and 12 months after transendocardial injection of autologous bone marrow mononuclear cells for ischemic cardiomyopathy. Circulation 2004; 110[suppl II]: II213- 8. (Pubitemid 39263725)
8. Schachinger V, Assmus B, Britten MB, Honold J, Lehmann R, Teupe C, et al. Transplantation of progenitor cells and regeneration enhancement in acute myocardial infarct: final one-year results of the TOPCARE-AMI trial. J Am Coll Cardiol 2004; 44: 1690-1699
9. Schachinger V, E rbs S, E lsasser A, H aberbosch W, Hambrecht R, Holschermann H, et al. Intracoronary bone marrow derived progenitor cells in acute myocardial infarction. New Engl J Med 2006; 355: 1210-1221
10. Stamm C, Kleine H, Choi Y, D unkelmann S, Lauffs J, Lorenzen B, et al. Intramyocardial delivery of CD133+ bone marrow cells and coronary artery bypass grafting for chronic ischemic heart disease: safety and effi cacy studies. J Thoracic Cardiovasc Surg 2007; 133: 717-725
11. Strauer B, B rehm M, Z eus T, K ostering M, H ernandez A, Sorg R, et al. Repair of infarcted myocardium by autologous intracoronary mononuclear bone marrow cell transplantation in humans. Circulation 2002; 106: 1913-1918
12. Wollert K, M eyer G, L otz J, R inges-Lichtenberg S, Lippolt P, Breidenbach C, et al. Intracoronary autologous bone-marrow cell transfer after myocardial infarction: the BOOST randomised controlled clinical trial. Lancet 2004; 364: 141-148
13. Penn MS. S tem-cell therapy after acute myocardial infarction: the focus should be on those at risk. Lancet 2006; 367: 87-88
14. Rosenzweig A. C ardiac cell therapy: mixed results from mixed cells. New Engl J Med 2006; 355: 1274-1276
15. Kocher A, S chuster M, S zabolcs M, T akuma S, B urkhoff D, Wang J, et al. Neovascularization of ischemic myo cardium by human bone-marrow derived angioblasts prevents cardiomyocyte apoptosis, reduced remodeling and improves cardiac function. Nature Med 2001; 7: 430-436
16. Badorff C, B randes R, Popp R, R upp S, Urbich C, A icher A, et al. Transdifferentiation of blood-derived human endothelial progenitor cells into functionally active cardiomyocytes. Circulation 2003; 107: 1024-1032
17. Yeh E, Zhang S, Wu H, Korbling M, W illerson J, Estrov Z. Transdifferentiation of human peripheral blood CD34+ -enriched cell population into cardiomyocytes, endothelial cells and smooth muscle cells in vivo. Circulation 2003; 108: 2070-2073
18. Thenon P, O jeda M, A rkam Y, S ovalat H, B ischoff N, Monassier J, et al. Intra-cardiac reinjection of purified autologous blood CD34+ cells mobilized by G-CSF can signifi cantly improve myocardial function in cardiac patients. Blood 2003; suppl 1 : 335a.
19. Ojeda-Uribe M, S ovalat H, B ourderont D, Brunot A, Marr A, Lewandowski H, et al. Peripheral blood and bone marrow CD34+CD38- cells show better resistance to cryopreservation than CD34+ CD38+ cells in autologous stem cells transplantation. Cytotherapy 2004; 6: 571-583
20. Bartunek J, D immeler S, D rexler H, F ernandez-Aviles F, Galinanes M, Janssens S, et al. The consensus of the task force of the European Society of Cardiology concerning the clinical investigation of the use of autologous adult stem cells for repair of the heart. Eur Heart J 2006; 27: 1338-1340
21. Menasche P, H agege A, V ilquin J, Desnos M, A bergel E, Pouzet B, et al. Autologous skeletal myoblast transplantation for severe postinfarction left ventricular dysfunction. J Am Coll Cardiol 2003; 41: 1078-1083
22. Jiang Y, Jahagirdar B, Reinhardt R, Schwartz R, Keene C, Ortiz-Gonzalez X, et al. Pluripotency of mesenchymal stem cells derived from adult marrow. Nature 2002; 418: 41-49
23. Berry M, E ngler A, Woo Y, Pirolli T, Bish L, J ayasankar V, et al. Mesenchymal stem cell injection after myocardial infraction improves myocardial compliance. Am J Physiol Heart Circ Physiol 2006; 290: H2196- 203.
24. Gordon M, L evicar N, Pai M, B achellier P, D imarakis I, Al-Allaf F, et al. Characterization and clinical application of human CD34+ stem/progenitor cell populations mobilized into the blood by granulocyte colony-stimulating factor. Stem Cells 2006; 24: 1822-1830
25. Kucia M, Reca R, Campbell F, Zuba-Surma E, Majka M, Ratajczak J, et al. A population of very small embryonic-like (VSEL) CXCR4- SSEA-1- OCT-4- stem cells identified in adult bone marrow. Leukemia 2006; 20: 857-869
26. Ratajczak M, K ucia M, R eca R, M ajka M, J anowska-Wieczorek A, Ratajczac J. Stem cell plasticity revisited: CXCR4- positive cells expressing mRNA for early muscle, liver and neural cells 'hide out' in the bone marrow. Leukemia 2004; 18: 29-40.
27. Yoon Y, Wecker A, Heyd L, Park J, Tkebuchava T, Kusano K, et al. Clonally expanded novel multipotent stem cells from human bone marrow regenerate myocardium after myocardial infarction. J Clin Invest 2005; 115: 326-338
28. Kucia M, H alasa M, W ysoczynski M, B askiewicz-Masiuk M, Moldenhawer S, Zuba-Surma E, et al. Morphological and molecular characterization of novel population of CXCR4- SSEA-4- OCT-4- very small embryonic-like cells purified from human cord blood: preliminary report. Leukemia 2007; 21: 297-303.
29. Goussetis E, Manginas A, K outelou M. Intracoronary infusion of CD133+ and CD133+ CD34+ selected autologous bone marrow progenitor cells in patients with chronic ischemic cardiomyopathy: cell isolation, adherence to the infarcted area and body distribution. Stem Cells 2006; 24: 2279-2283
30. Pompilio G, Cannata A, P eccatori F, Bertolini F, Nascimbene A, Capogrossi M, et al. Autologous peripheral blood stem cell transplantation for myocardial regeneration: a novel strategy for cell collection and surgical injection. Ann Thoracic Surg 2004; 78: 1808-1813
31. Balsam L, Wagers A, C hristensen J, Kofi dis T, Weissman I, Robbins R. Haematopoietic stem cells adopt mature haematopoietic fates in ischemic myocardium. Nature 2004; 428: 668-673
32. Murry C, S oonpaa M, R einecke H, N akajima H, Nakajima HO, Rubart M, et al. Haematopoietic stem cells do not transdifferentiate into cardiac myocytes in myocardial infarcts. Nature 2004; 428: 664-668
33. Thenon P, S ovalat H, Becker M, Arkam Y, Ojeda-Uribe M, Raidot J, et al. Primordial role of CD34+ 38+ cells in early and late trilineage haemopoietic engraftment after autologous blood cell transplantation. Br J Haematol 1998; 103: 568-581
34. Wojakowski W, T endera M, M ichalowska A, M ajka M, Kucia M, Maslankiewicz K, et al. Mobilization of CD34/ CXCR4- , CD34/CD117- , c-met- stem cells, and mononuclear cells expressing early cardiac, muscle, and endothelial markers into peripheral blood in patients with acute myocardial infarction. Circulation 2004; 110: 3213-3220
35. Theiss HD, David R, Engelmann MG, Barth A, Schotten K, Naebauer M, et al. Circulation of CD34+ progenitor cell populations in patients with idiopathic dilated and ischaemic cardiomyopathy (DCM and ICM). Eur Heart J 2007; 28: 1258-1264
36. Orlic D, Kajstura J, C himenti S, L imana F, J akoniuk I, Quaini F, et al. Mobilized bone marrow cells repair the infarcted heart, improving function and survival. Proc Natl Acad Sci USA 2001; 98: 10344-10349
37. Norol F, M erlet P, I snard R, S ebillon P, B onnet N, C ailliot C, et al. Influence of mobilized stem cells on myocardial infarct repair in a nonhuman primate model. Blood 2003; 102: 4361-4368
38. Ellis SG, Penn MS, B olwell B, Garcia M, Chacko M, Wang T, et al. Granulocyte colony stimulating factor in patients with large acute myocardial infarction: results of a pilot dose-escalation randomized trial. Am Heart J 2006; 152: 1051.e9-14
39. Meyer GP, Wollert KC, L otz J, S teffens J, L ippolt P, Fichtner S, et al. Intracoronary bone marrow cell transfer after myocardial infarction: eighteen months follow-up date from the randomized, controlled BOOST (Bone MarrOw transfer to enhance ST-elevation infarct regeneration) trial. Circulation 2006; 113: 1287-1294
40. Ebelt H, Jungblut M, Zhang Y, K ubin T, K ostin S, Technau A, et al. Cellular cardiomyoplasty: improvement of left ventricular function correlates with the release of cardioactive cytokines. Stem Cells 2007; 25: 236-244