Synthesis and anticancer activity of novel amide derivatives of non-acetal deoxoartemisinin

Bioorganic and Medicinal Chemistry Letters

Volumn 19, Issue 22, 2009, Pages 6303-6306

  Jung, Mankil ^a   Park, Namsoo ^a   Moon, Hyung In ^b   Lee, Yongnam ^a   Chung, Won Yoon ^c   Park, Kwang Kyun ^c  

^a Yonsei University   (South Korea)

^b Sanbon Medical Center   (South Korea)

^c Yonsei University College of Dentistry   (South Korea)

Author keywords

Antiangiogenesis; Anticancer activity; Deoxoartemisinin; Non acetal type

Indexed keywords

11 ALPHA 13 BROMODEOXO ARTEMISININ; 12 CARBOXYETHYLDEOXOARTEMISININ; AMIDE; ARTEMETHER; ARTEMISININ; ARTEMISININ DERIVATIVE; DEOXOARTEMISININ; DIHYDROARTEMISININ; MATRIGEL; UNCLASSIFIED DRUG;

ANTIANGIOGENIC ACTIVITY; ANTINEOPLASTIC ACTIVITY; ARTICLE; ASSAY; CANCER CELL CULTURE; CONTROLLED STUDY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY;

ACETALS; AMIDES; ANIMALS; APOPTOSIS; ARTEMISININS; CELL PROLIFERATION; DRUG DESIGN; DRUG SCREENING ASSAYS, ANTITUMOR; ENDOTHELIUM, VASCULAR; HUMANS; INHIBITORY CONCENTRATION 50; MICE; MICE, NUDE; NEOPLASM TRANSPLANTATION; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 71049195428     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2009.09.093     Document Type: Article

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