Aberrant DNA polymerase α is excluded from the nucleus by defective import and degradation in the nucleus

Journal of Biological Chemistry

Volumn 284, Issue 44, 2009, Pages 30604-30614

  Eichinger, Christian S ^a,d   Mizuno, Takeshi ^a,b   Mizuno, Keiko ^a   Miyake, Yasuyuki ^a,e   Yanagi, Ken Ichiro ^a   Imamoto, Naoko ^a   Hanaoka, Fumio ^a,b,c,f  

^a RIKEN   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^c OSAKA UNIVERSITY   (Japan)

^d MAX PLANCK INSTITUTE OF BIOCHEMISTRY   (Germany)

^e KYOTO UNIVERSITY   (Japan)

^f GAKUSHUIN UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CELL-CYCLE PROGRESSION; DNA POLYMERASE; DNA REPLICATIONS; ENHANCED GREEN FLUORESCENT PROTEIN; GREEN FLUORESCENT PROTEIN; INHIBITOR ANALYSIS; MOUSE CELL LINES; NUCLEAR IMPORT; PHOTOACTIVATABLE; PREINITIATION COMPLEX; PROTEASOMES; PROTEIN LEVEL; RNA INTERFERENCE; S-PHASE; SINGLE-POINT MUTATION; TEMPERATURE-SENSITIVE; WILD TYPES;

CELL CULTURE; DEGRADATION; DNA; FLUORESCENCE; FLUORESCENCE MICROSCOPY; GENES; POLYMERS; PROTEINS; RNA; SYNTHESIS (CHEMICAL);

NUCLEIC ACIDS;

DNA DIRECTED DNA POLYMERASE ALPHA; GENE PRODUCT; PROTEASOME; PROTEIN P180; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL CULTURE; CELL NUCLEUS; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOPLASM; DNA REPLICATION; FLUORESCENCE MICROSCOPY; GENETIC VARIABILITY; MOUSE; NONHUMAN; PLASMID; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN SYNTHESIS; RNA INTERFERENCE; TEMPERATURE DEPENDENCE;

3T3 CELLS; ACTIVE TRANSPORT, CELL NUCLEUS; ANIMALS; CELL NUCLEUS; CYTOPLASM; DNA POLYMERASE I; MICE; MICROSCOPY, FLUORESCENCE; MUTANT PROTEINS; PROTEASOME ENDOPEPTIDASE COMPLEX;

EID: 71049192822     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.024760     Document Type: Article

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