Caenorhabditis elegans galectins LEC-6 and LEC-1 recognize a chemically synthesized Galβ1-4Fuc disaccharide unit which is present in Protostomia glycoconjugates

Glycobiology

Volumn 19, Issue 12, 2009, Pages 1503-1510

  Takeuchi, Tomoharu ^a   Nishiyama, Kazusa ^a   Sugiura, Ken Ichi ^a   Takahashi, Miki ^a   Yamada, Atsushi ^a   Kobayashi, Susumu ^b   Takahashi, Hideyo ^a   Natsugari, Hideaki ^a   Kasai, Ken Ichi ^a  

^a TEIKYO UNIVERSITY   (Japan)

^b TOKYO UNIVERSITY OF SCIENCE   (Japan)

Author keywords

Caenorhabditis elegans; Frontal affinity chromatography; Gal 1 4Fuc; Gal 1 4GlcNAc; Galectin

Indexed keywords

2 AMINOPYRIDINE; DISACCHARIDE; GALACTOSE BETA1 3FUCOSE; GALACTOSE BETA1 4FUCOSE; LECTIN; LECTIN 1; LECTIN 6; UNCLASSIFIED DRUG;

AFFINITY CHROMATOGRAPHY; ARTICLE; CAENORHABDITIS ELEGANS; CARBOHYDRATE ANALYSIS; CARBOHYDRATE SYNTHESIS; CONTROLLED STUDY; HEMAGGLUTINATION; MOLECULAR RECOGNITION; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CARBOHYDRATE INTERACTION;

AMINO ACID SEQUENCE; ANIMALS; ANTIGENS, HELMINTH; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; CARBOHYDRATE SEQUENCE; DISACCHARIDES; GALECTINS; GLYCOCONJUGATES; MODELS, BIOLOGICAL; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; PROTEIN INTERACTION DOMAINS AND MOTIFS; SUBSTRATE SPECIFICITY;

CAENORHABDITIS ELEGANS; PROTOSTOMIA; VERTEBRATA;

EID: 71049177754     PISSN: 09596658     EISSN: 14602423     Source Type: Journal    
DOI: 10.1093/glycob/cwp125     Document Type: Article

References (29)

1. Arata Y, Hirabayashi J, Kasai K. 1997. The two lectin domains of the tandem-repeat 32-kDa galectin of the nematode Caenorhabditis elegans have different binding properties. Studies with recombinant protein. J Biochem. 121:1002-1009.
2. Arata Y, Hirabayashi J, Kasai K. 2001. Sugar binding properties of the two lectin domains of the tandem repeat-type galectin LEC-1 (N32) of Caenorhabditis elegans. Detailed analysis by an improved frontal affinity chromatography method. J Biol Chem. 276:3068-3077.
3. Cipollo JF, Awad AM, Costello CE, Hirschberg CB. 2005. N-Glycans of Caenorhabditis elegans are specific to developmental stages. J Biol Chem. 280:26063-26072.
4. Cooper DN. 2002. Galectinomics: Finding themes in complexity. Biochim Biophys Acta. 1572:209-231.
5. Griffitts JS, Haslam SM, Yang T, Garczynski SF, Mulloy B, Morris H, Cremer PS, Dell A, Adang MJ, Aroian RV. 2005. Glycolipids as receptors for Bacillus thuringiensis crystal toxin. Science. 307:922-925.
6. Guerardel Y, Balanzino L, Maes E, Leroy Y, Coddeville B, Oriol R, Strecker G. 2001. The nematode Caenorhabditis elegans synthesizes unusual O-linked glycans: Identification of glucose-substituted mucin-type O-glycans and short chondroitin-like oligosaccharides. Biochem J. 357:167-182.
7. Gutternigg M, Kretschmer-Lubich D, Paschinger K, Rendic D, Hader J, Geier P, Ranftl R, Jantsch V, Lochnit G, Wilson IB. 2007. Biosynthesis of truncated N-linked oligosaccharides results from non-orthologous hexosaminidase-mediated mechanisms in nematodes, plants, and insects. J Biol Chem. 282:27825-27840.
8. Hanneman AJ, Rosa JC, Ashline D, Reinhold VN. 2006. Isomer and glycomer complexities of core GlcNAcs in Caenorhabditis elegans. Glycobiology 16:874-890.
9. Hirabayashi J, Hashidate T, Arata Y, Nishi N, Nakamura T, Hirashima M, Urashima T, Oka T, Futai M, Muller WE, et al. 2002. Oligosaccharide specificity of galectins: A search by frontal affinity chromatography. Biochim Biophys Acta. 1572:232-254.
10. Hirabayashi J, Kasai K. 1988. Complete amino acid sequence of a β-galactoside-binding lectin from human placenta. J Biochem. 104:1-4.
11. Hirabayashi J, Kasai K. 1991. Effect of amino acid substitution by sited-directed mutagenesis on the carbohydrate recognition and stability of human 14-kDa β-galactoside-binding lectin. J Biol Chem. 266:23648-23653.
12. Hirabayashi J, Satoh M, Kasai K. 1992. Evidence that Caenorhabditis elegans 32-kDa β-galactoside-binding protein is homologous to vertebrate β-galactoside-binding lectins. cDNA cloning and deduced amino acid sequence. J Biol Chem. 267:15485-15490.
13. Hirabayashi J, Satoh M, Ohyama Y, Kasai K. 1992. Purification and characterization of β-galactoside-binding proteins from Caenorhabditis elegans. J Biochem. 111:553-555.
14. Hirabayashi J, Ubukata T, Kasai K. 1996. Purification and molecular characterization of a novel 16-kDa galectin from the nematode Caenorhabditis elegans. J Biol Chem. 271:2497-2505.
15. Kasai K, Hirabayashi J. 1996. Galectins: A family of animal lectins that decipher glycocodes. J Biochem. 119:1-8.
16. Kasai K, Oda Y, Nishikata M, Ishii S. 1986. Frontal affinity chromatography: Theory for its application to studies on specific interactions of biomolecules. J Chromatogr. 376:33-47.
17. Lobsanov YD, Gitt MA, Leffler H, Barondes SH, Rini JM. 1993. X-ray crystal structure of the human dimeric S-Lac lectin, L-14-II, in complex with lactose at 2.9-A resolution. J Biol Chem. 268:27034-27038.
18. Nemoto-Sasaki Y, Hayama K, Ohya H, Arata Y, Kaneko MK, Saitou N, Hirabayashi J, Kasai K. 2008. Caenorhabditis elegans galectins LEC-1- LEC-11: Structural features and sugar-binding properties. Biochim Biophys Acta. 1780:1131-1142.
19. Pace KE, Baum LG. 2004. Insect galectins: Roles in immunity and development. Glycoconj J. 19:607-614.
20. Pace KE, Lebestky T, Hummel T, Arnoux P, Kwan K, Baum LG. 2002. Characterization of a novel Drosophila melanogaster galectin. Expression in developing immune, neural, and muscle tissues. J Biol Chem. 277:13091-13098.
21. Paschinger K, Gutternigg M, Rendic D, Wilson IB. 2008. The N glycosylation pattern of Caenorhabditis elegans. Carbohydr Res. 343:2041-2049.
22. Rabinovich GA, Toscano MA, Jackson SS, Vasta GR. 2007. Functions of cell surface galectin-glycoprotein lattices. Curr Opin Struct Biol. 17:513-520.
23. Schachter H. 2004. Protein glycosylation lessons from Caenorhabditis elegans. Curr Opin Struct Biol. 14:607-616.
24. Takahashi N, Masuda K, Hiraki K, Yoshihara K, Huang HH, Khoo KH, Kato K. 2003. N-Glycan structures of squid rhodopsin. Eur J Biochem. 270:2627-2632.
25. Takeuchi T, Hayama K, Hirabayashi J, Kasai K. 2008. Caenorhabditis elegans N-glycans containing a Gal-Fuc disaccharide unit linked to the innermost GlcNAc residue are recognized by C. elegans galectin LEC-6. Glycobiology. 18:882-890.
26. Takeuchi T, Sennari R, Sugiura K, Tateno H, Hirabayashi J, Kasai K. 2008. A C-type lectin of Caenorhabditis elegans: Its sugar-binding property revealed by glycoconjugate microarray analysis. Biochem Biophys Res Commun. 377:303-306.
27. Vasta GR, Ahmed H, Odom EW. 2004. Structural and functional diversity of lectin repertoires in invertebrates, protochordates and ectothermic vertebrates. Curr Opin Struct Biol. 14:617-630.
28. Wuhrer M, Robijn ML, Koeleman CA, Balog CI, Geyer R, Deelder AM, Hokke CH. 2004. A novel Gal(β1-4)Gal(β1-4)Fuc(α1-6)-core modification attached to the proximal N-acetylglucosamine of keyhole limpet haemocyanin (KLH) N-glycans. Biochem J. 378:625-632.
29. Zhang Y, Iwasa T, Tsuda M, Kobata A, Takasaki S. 1997. A novel monoantennary complex-type sugar chain found in octopus rhodopsin: Occurrence of the Galβ1-4Fuc group linked to the proximal N acetylglucosamine residue of the trimannosyl core. Glycobiology 7:1153-1158.