Lymphangiogenic characteristics of triple negativity in node-negative breast cancer

International Journal of Surgical Pathology

Volumn 17, Issue 6, 2009, Pages 426-431

  Liu, Huan Tao ^a   Ma, Rong ^a   Yang, Qi Feng ^a   Du, Gang ^a   Zhang, Cui Juan ^a  

^a SHANDONG UNIVERSITY   (China)

Author keywords

Breast cancer; Lymphangiogenesis; Lymphatic vessel density; Triple negative; VEGF C; VEGF D

Indexed keywords

VASCULOTROPIN C; VASCULOTROPIN D;

ADULT; ARTICLE; BREAST CANCER; CANCER INVASION; CONTROLLED STUDY; HISTOLOGY; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; LYMPH NODE; LYMPH VESSEL; LYMPHANGIOGENESIS; MAJOR CLINICAL STUDY; PATHOLOGY; PRIORITY JOURNAL; TUMOR VOLUME;

ADENOCARCINOMA; ADULT; BREAST NEOPLASMS; ESTROGEN RECEPTOR ALPHA; FEMALE; HUMANS; IMMUNOENZYME TECHNIQUES; LYMPH NODES; LYMPHANGIOGENESIS; LYMPHATIC VESSELS; NEOPLASM INVASIVENESS; NEOPLASM STAGING; RECEPTOR, ERBB-2; RECEPTORS, PROGESTERONE; TUMOR MARKERS, BIOLOGICAL; VASCULAR ENDOTHELIAL GROWTH FACTOR C; VASCULAR ENDOTHELIAL GROWTH FACTOR D;

EID: 71049168307     PISSN: 10668969     EISSN: 19402465     Source Type: Journal    
DOI: 10.1177/1066896909337505     Document Type: Article

References (18)

1. Bauer KR, Brown M., Cress RD, Parise CA, Caggiano V. Descriptive analysis of estrogen receptor (ER)-negative, progesterone receptor (PR)-negative, and HER2-negative invasive breast cancer, the so-called triple-negative phenotype: a population-based study from the California Cancer Registry. Cancer. 2007 ; 109: 1721-1728.
2. Dent R., Trudeau M., Pritchard KI, et al. Triple-negative breast cancer: clinical features and patterns of recurrence. Clin Cancer Res. 2007 ; 13: 4429-4434.
3. Haffty BG, Yang Q., Reiss M., et al. Locoregional relapse and distant metastasis in conservatively managed triple negative early-stage breast cancer. J Clin Oncol. 2006 ; 24: 5652-5657.
4. Rhee J., Han SW, Oh DY, et al. The clinicopathologic characteristics and prognostic significance of triple-negativity in node-negative breast cancer. BMC Cancer. 2008 ; 8: 307.
5. Mohammed RA, Ellis IO, Elsheikh S., Paish EC, Martin SG Lymphatic and angiogenic characteristics in breast cancer: morphometric analysis and prognostic implications. Breast Cancer Res Treat. 2009 ; 113: 261-273.
6. Eccles S., Paon L., Sleeman J. Lymphatic metastasis in breast cancer: importance and new insights into cellular and molecular mechanisms. Clin Exp Metastasis. 2007 ; 24: 619-636.
7. Gu Y., Qi X., Guo S. Lymphangiogenesis induced by VEGF-C and VEGF-D promotes metastasis and a poor outcome in breast carcinoma: a retrospective study of 61 cases. Clin Exp Metastasis. 2008 ; 25: 717-725.
8. Kadota K., Huang CL, Liu D., et al. The clinical significance of lymphangiogenesis and angiogenesis in non-small cell lung cancer patients. Eur J Cancer. 2008 ; 44: 1057-1067.
9. Weidner N. Current pathologic methods for measuring intratumoral microvessel density within breast carcinoma and other solid tumors. Breast Cancer Res Treat. 1995 ; 36: 169-180.
10. Zhang XH, Huang DP, Guo GL, et al. Coexpression of VEGF-C and COX-2 and its association with lymphangiogenesis in human breast cancer. BMC Cancer. 2008 ; 8: 4.
11. Dogu GG, Ozkan M., Ozturk F., Dikilitas M., Er O., Ozturk A. Triple-negative breast cancer: immunohistochemical correlation with basaloid markers and prognostic value of surviving [published online ahead of print January 21, 2009 ]. Med Oncol. doi: 10.1007/ s12032-009-9166-3.
12. Lund MJ, Trivers KF, Porter PL, et al. Race and triple negative threats to breast cancer survival: a population-based study in Atlanta, GA. Breast Cancer Res Treat. 2009 ; 113: 357-370.
13. Umemura S., Yoshida S., Ohta Y., et al. Increased phosphorylation of Akt in triple-negative breast cancers. Cancer Sci. 2007 ; 98: 1889-1892.
14. Uematsu T., Kasami M., Yuen S. Triple-negative breast cancer: correlation between MR imaging and pathologic findings. Radiology. 2009 ; 250: 638-647.
15. Williams CS, Leek RD, Robson AM, et al. Absence of lymphangiogenesis and intratumoural lymph vessels in human metastatic breast cancer. J Pathol. 2003 ; 200: 195-206.
16. Ji RC Lymphatic endothelial cells, tumor lymphangiogenesis and metastasis: new insights into intratumoral and peritumoral lymphatics. Cancer Metastasis Rev. 2006 ; 25: 677-694.
17. Teramoto S., Arihiro K., Koseki M., Kataoka T., Asahara T., Ohdan H. Role of vascular endothelial growth factor-C and -D mRNA in breast cancer. Hiroshima J Med Sci. 2008 ; 57: 73-78.
18. Tan AR, Swain SM Therapeutic strategies for triple-negative breast cancer. Cancer J. 2008 ; 14: 343-351.