Identification of the amino acid-AZT-phosphoramidase by affinity T7 phage display selection

Bioorganic and Medicinal Chemistry Letters

Volumn 19, Issue 22, 2009, Pages 6379-6381

  Cheng, Jilin ^a,b   Zhou, Xin ^a   Chou, Tsui Fen ^a   Ghosh, Brahma ^a   Liu, Baoling ^a   Wagner, Carston R ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

^b SHANGHAI PUBLIC HEALTH CLINICAL CENTER   (China)

Author keywords

AZT; Hint1; Phosphoramidate; Prodrug; Pronucleotide

Indexed keywords

CARBAMIC ACID DERIVATIVE; COMPLEMENTARY DNA; NUCLEOTIDE; PRONUCLEOTIDE; RIBONUCLEOTIDE; UNCLASSIFIED DRUG; ZIDOVUDINE;

AMINO ACID ANALYSIS; ARTICLE; BACTERIOPHAGE T7; CELL LINE; CONTROLLED STUDY; DRUG BINDING; DRUG IDENTIFICATION; DRUG SYNTHESIS; ENZYME ACTIVITY; GENE LIBRARY; HUMAN; HUMAN CELL; HYDROLYSIS; PHAGE DISPLAY; SCREENING TEST;

AMIDES; AMINO ACIDS; ANTI-HIV AGENTS; BACTERIOPHAGE T7; CYTARABINE; DRUG DELIVERY SYSTEMS; DRUG DESIGN; HUMANS; PEPTIDE LIBRARY; PHOSPHORIC ACIDS; VIRUS REPLICATION; ZIDOVUDINE;

EID: 71049166830     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2009.09.067     Document Type: Article

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