Multiple immune abnormalities in a patient with idiopathic CD4+ T-lymphocytopenia

Internal Medicine

Volumn 48, Issue 22, 2009, Pages 1967-1971

  Yamada, Yasuaki ^a   Okada, Masahiko ^a   Kamitamari, Akira ^a   Moriuchi, Hiroyuki ^a   Yanai, Masanori ^b   Hano, Osamu ^c   Tsukasaki, Kunihiro ^a   Tsuruda, Kazuto ^a   Hasegawa, Hiroo ^a   Yanagihara, Katsunori ^a   Kamihira, Shimeru ^a  

^a NAGASAKI UNIVERSITY HOSPITAL   (Japan)

^b Yanai Children's Clinic   (Japan)

^c Hano Clinic   (Japan)

Author keywords

CD4; ICL; T lymphocytopenia

Indexed keywords

ERYTHROPOIETIN; FLUCONAZOLE; PREDNISOLONE; VIRUS ANTIBODY;

ADULT; ANAMNESIS; ARTICLE; AUTOIMMUNE HEMOLYTIC ANEMIA; CASE REPORT; CD4 CD8 RATIO; CD4 LYMPHOCYTE COUNT; CONJUNCTIVAL HYPEREMIA; CRYPTOCOCCOSIS; CYTOMEGALOVIRUS; DRUG PULSE THERAPY; EPSTEIN BARR VIRUS; ERYTHROCYTE COUNT; HUMAN; HUMAN TISSUE; HYPOPROTEINEMIA; IDIOPATHIC THROMBOCYTOPENIC PURPURA; IMMUNOPATHOLOGY; LYMPH NODE BIOPSY; LYMPHADENITIS; LYMPHADENOPATHY; LYMPHOCYTOPENIA; MALE; MEASLES; MONOCLONAL IMMUNOGLOBULINEMIA; MUCOSA ASSOCIATED LYMPHOID TISSUE LYMPHOMA; PLASMAPHERESIS; PNEUMONIA; POLYCYTHEMIA; PROTEIN BLOOD LEVEL; RECURRENT DISEASE; RHEUMATOID ARTHRITIS; VIRUS INFECTION;

ADULT; HUMANS; IMMUNE SYSTEM DISEASES; MALE; T-LYMPHOCYTOPENIA, IDIOPATHIC CD4-POSITIVE;

EID: 71049147215     PISSN: 09182918     EISSN: 13497235     Source Type: Journal    
DOI: 10.2169/internalmedicine.48.2623     Document Type: Article

References (15)

1. Anonymous. Unexplained CD4+ T-lymphocyte depletion in persons without evident HIV infection-United States. MMWR Morb Mortal Wkly Rep 41: 541-545, 1992.
2. Saiki O, Ogawa H, Ikeda T, et al. Acquired T cell specific deficiency other than acquired immunodeficiency syndrome (AIDS). Intern Med 31: 11-16, 1992.
3. Duncan RA, von Reyn CF, Alliegro GM, Toossi Z, Sugar AM, Levitz SM. Idiopathic CD4+ T-lymphocytopenia: four patients with opportunistic infections and no evidence of HIV infection. N Engl J Med 328: 393-398, 1993. (Pubitemid 23042287)
4. Ho DD, Cao Y, Zhu T, et al. Idiopathic CD4+ T-lymphocytopenia: immunodeficiency without evidence of HIV infection. N Engl J Med 328: 380-385, 1993. (Pubitemid 23042285)
5. Smith DK, Neal JJ, Holmberg SD. Unexplained opportunistic infections and CD4+ T-lymphocytopenia without HIV infection: an investigation of cases in the United States. The Centers for Disease Control Idiopathic CD4+ T-lymphocytopenia Task Force. N Engl J Med 328: 373-379, 1993.
6. Spira TJ, Jones BM, Nicholson JK, et al. Idiopathic CD4+ Tlymphocytopenia: an analysis of five patients with unexplained opportunistic infections. N Engl J Med 328: 386-392, 1993. (Pubitemid 23042286)
7. Fauci AS. CD4+ T-lymphocytopenia without HIV infection: no lights, no camera, just facts. N Engl J Med 328: 429-431, 1993.
8. Zonios DI, Falloon J, Bennett JE, et al. Idiopathic CD4+ lymphocytopenia: natural history and prognostic factors. Blood 112: 287-294, 2008.
9. Kutukculer N, Aksu G, Genel F, Ozturk C. Idiopathic CD4+ T cell lymphocytopenia with the absence of B cells and CD8+28+ cells in peripheral blood. Clin Exp Med 2: 143-146, 2002. (Pubitemid 35439567)
10. Fruhwirth M, Clodi K, Heltger A, Neu N. Lymphocyte diversity in a 9-year-old boy with idiopathic CD4+ T cell lymphocytopenia. Int Arch Allergy Immunol 125: 80-85, 2001. (Pubitemid 32511104)
11. Anonymous. 1993 revised classification system for HIV infection and expanded surveillance case definition of AIDS among adolescents and adults. MMWR Recomm Rep 41: 1-19, 1992.
12. Belmin J, Ortega MN, Bruhat A, Mercadier A, Valensi P. CD4+ lymphocytopenia in very elderly people. Lancet 347: 328-329, 1996.
13. Matsuyama W, Mizoguchi A, Hamasaki T, et al. Idiopathic CD4+ T-lymphocytopenia in chronic obstructive pulmonary disease. Intern Med 38: 71-72, 1999.
14. Salit RB, Hankey KG, Yi R, Rapoport AP, Mann DL. Detection of CD4(+) T-cell antibodies in a patient with idiopathic CD4 T lymphocytopenia and cryptococcal meningitis. Br J Haematol 139: 133-137, 2007. (Pubitemid 47389939)
15. Roger PM, Bernard-Pomier G, Counillon E, Breittmayer JP, Bernard A, Dellamonica P. Overexpression of Fas/CD95 and Fasinduced apoptosis in a patient with idiopathic CD4+ T lymphocytopenia. J Infect Dis 28: 1012-1016, 1999.