Remission from transfusion-dependence in a patient with congenital dyserythropoietic anemia (CDA) and increased intensity of iron chelation

Pediatric Blood and Cancer

Volumn 53, Issue 6, 2009, Pages 1167-1168

  Bergmann, Anke K ^a   Tamary, Hannah ^b,c   Neufeld, Ellis J ^a,d  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b SCHNEIDER CHILDREN S MEDICAL CENTER OF ISRAEL   (Israel)

^c TEL AVIV UNIVERSITY   (Israel)

^d DANA FARBER CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

5 AMINOLEVULINATE SYNTHASE; DEFEROXAMINE; HEME; HEMOGLOBIN; IRON;

ADOLESCENT; BONE MARROW BIOPSY; CASE REPORT; COMPARATIVE GENOMIC HYBRIDIZATION; CONGENITAL DYSERYTHROPOIETIC ANEMIA; DIABETES MELLITUS; ERYTHROBLAST; ERYTHROCYTE TRANSFUSION; ERYTHROPOIESIS; FACE DYSMORPHIA; GENE MUTATION; GENETIC VARIABILITY; GROWTH RETARDATION; HEMOGLOBIN BLOOD LEVEL; HOME CARE; HUMAN; HYPOGONADOTROPIC HYPOGONADISM; IRON CHELATION; IRON OVERLOAD; KARYOTYPE; LETTER; LIVER CIRRHOSIS; LUNG DYSPLASIA; MALE; MICROCEPHALY; MUSCLE SPASM; MYOCLONUS SEIZURE; NEWBORN INTENSIVE CARE; PREMATURITY; PRIORITY JOURNAL; PSYCHOMOTOR RETARDATION; QUADRIPLEGIA; REMISSION; TREATMENT RESPONSE;

ADOLESCENT; ANEMIA, DYSERYTHROPOIETIC, CONGENITAL; BLOOD TRANSFUSION; DEFEROXAMINE; ERYTHROPOIESIS; HUMANS; IRON CHELATING AGENTS; MALE; REMISSION INDUCTION; SIDEROPHORES;

EID: 71049133629     PISSN: 15455009     EISSN: 15455017     Source Type: Journal    
DOI: 10.1002/pbc.22204     Document Type: Letter

References (5)

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2. Bottomley SS. Congenital sideroblastic anemias. Curr Hematol Rep 2006;5:41-49.
3. Camaschella C, Campanella A, De Falco L, et al. The human counterpart of zebrafish shiraz shows sideroblastic-like microcytic anemia and iron overload. Blood 2007;110:1353-1358. (Pubitemid 47281436)
4. Cotter PD, May A, Li L, et al. Four new mutations in the erythroidspecific 5-aminolevulinate synthase (ALAS2) gene causing X-linked sideroblastic anemia: increased pyridoxine responsiveness after removal of iron overload by phlebotomy and coinheritance of hereditary hemochromatosis. Blood 1999;93:1757-1769. (Pubitemid 29102505)
5. Vreugdenhil G, Smeets M, Feelders RA, et al. Iron chelators may enhance erythropoiesis by increasing iron delivery to haematopoietic tissue and erythropoietin response in iron-loading anaemia. Acta Haematol 1993;89:57-60. (Pubitemid 23193193)