Circulating nerve growth factor in primary and secondary Raynaud's syndrome - Results of a pilot study

Vasa - Journal of Vascular Diseases

Volumn 38, Issue 1, 2009, Pages 39-45

  Klein Weigel, Peter Franz ^a   Gutsche Petrak, B ^a   Humpel, C ^e   Riemekasten, G ^b   Ivanov, S ^c   Heidrich, H ^d  

^a German Red Cross Hospital   (Germany)

^b CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^c HUMBOLDT UNIVERSITY   (Germany)

^d MARTIN LUTHER KRANKENHAUS   (Germany)

^e INNSBRUCK MEDICAL UNIVERSITY   (Austria)

Author keywords

Nerve growth factor; Neurotrophins; Raynaud's phenomenon; Scleroderma; Systemic sclerosis; Vasospasm

Indexed keywords

NERVE GROWTH FACTOR; DIAGNOSTIC AGENT;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; COLD; CONTROLLED STUDY; DISEASE DURATION; DISEASE SEVERITY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; MALE; PILOT STUDY; PLETHYSMOGRAPHY; RAYNAUD PHENOMENON; SYMPTOMATOLOGY; SYSTEMIC SCLEROSIS; VASOSPASM; BLOOD; CASE CONTROL STUDY; FINGER; HOSPITALIZATION; MIDDLE AGED; PATHOPHYSIOLOGY; TIME; VASCULARIZATION; VASOCONSTRICTION;

ADULT; AGED; CASE-CONTROL STUDIES; COLD TEMPERATURE; ENZYME-LINKED IMMUNOSORBENT ASSAY; FINGERS; HUMANS; MIDDLE AGED; NERVE GROWTH FACTOR; PILOT PROJECTS; PLETHYSMOGRAPHY; RAYNAUD DISEASE; SCLERODERMA, SYSTEMIC; SEVERITY OF ILLNESS INDEX; TIME FACTORS; VASOCONSTRICTION; YOUNG ADULT;

EID: 71049116861     PISSN: 03011526     EISSN: None     Source Type: Journal    
DOI: 10.1024/0301-1526.38.1.39     Document Type: Article

References (36)

1. Allen SJ, Dawbarn D. Clinical relevance of the neurotrophins and their receptors. Clin Sci 2006; 110: 175-91.
2. Alleva E, Santucci D. Psychosocial vs. "physical" stress situations in rodents and humans. Role of neurotrophins. Physiol Behav 2001; 73: 313-20.
3. Aloe L, Tuveri MA. Nerve growth factor and autoimmune rheumatic diseases. Clin Exp Rheumatol 1997; 15: 433-8.
4. Anand P. Neurotrophic factors and their receptors in human sensory neuropathies. Prog Brain Res 2004; 146: 477-92.
5. Barbacid M. The Trk family of neurotrophin receptors. J Neurobiol 1994; 25: 1386-403.
6. Berkemeier LR, Winslow JW, Kaplan DR, Nikolics K, Goeddel DV, Rosenthal A. Neurotrophina novel neurotrophic factor that activates trk and trkB. Neuron 1991; 7: 857-66.
7. Blasing H, Hendrix S, Paus R. Pro-inflammatory cytokines upregulate the skin immunoreactivity for NGF, NT-3, NT-4 and their receptor, p75NTR in vivo: a preliminary report. Arch Dermatol Res 2005; 296: 580-4.
8. Boyd JG, Gordon T. Neurotrophic factors and their receptors in axonal regeneration and functional recovery after peripheral nerve injury. Mol Neurobiol 2003; 27: 277-324.
9. Chaldakov GN, Fiore M, Stankulov IS, Manni L, Hristova MG, Antonelli A, Ghenev PI, Aloe L. Neurotrophin presence in human coronary atherosclerosis and metabolic syndrome: a role for NGF and BDNF in cardiovascular disease? Prog Brain Res 2004; 146: 279-89.
10. Chao MV. Neurotrophin receptors: a window into neuronal differentiation. Neuron 1992; 9: 583-93.
11. Duman RS. Neurotrophic factors and regulation of mood:role of exercise, diet and metabolism. Neurobiol Aging 2005; 26S: 88-93.
12. Ejiri J, Inoue N, Kobayashi S, Shiraki R, Otsui K, Honjo T, Takahashi M, Ohashi Y, Ichikawa S, Terashima M, Mori T, Awano K, Shinke T, Shite J, Hirata K, Yokozaki H, Kawashima S, Yokoyama M. Possible role of Brain-Derived Neurotrophic Factor in the pathogenesis of coronary artery disease.Circulation 2005; 112: 2114-20.
13. Emanueli C, Salis MB, Pinna A, Graiani G, Manni L, Madeddu P. Nerve growth factor promotes angiogenesis and arteriogenesis in ischemic hindlimbs. Circulation 2002; 106: 2257-62.
14. Gerasimova MM, Cherdyntsev MG. [Clinical, immunological, and electrophysiological matching in Raynaud's syndrome] [Article in Russian]. Klin Med 2005; 83: 62-6.
15. Hohn A, Leibrock J, Bailey K, Barde YA. Identification and characterization of a novel member of the nerve growth factor/ brain-derived neurotrophic factor family. Nature 1990; 344: 339-41.
16. Hunzelmann N, Genth E, Krieg T, Lehmacher W, Melchers I, Meurer M, Moinzadeh P, Müller-Ladner U, Pfeiffer C, Riemekasten G, Schulze-Lohoff E, Sunderkoetter C, Weber M, Worm M, Klaus P, Rubbert A, Steinbrink K, Grundt B, Hein R, Scharffetter-Kochanek K, Hinrichs R, alker K, Szeimies R-M, Karrer S, Müller A, Seitz C, Schmidt E, Lehmann P, Foeldvari I, Reichenberger F, Gross WL, Kuhn A, Haust M, Reich K, Bohm M, Saarl P, Fierlbeck G, Kotter I, Lorenz H-M, Blank N, Grafenstein K, Juche A, Aberer E, Bali G, Fiehn C, Stadler R and Bartels V. The registry of the German Network for Systemic Scleroderma: Frequency of disease subsets and patterns of organ involvement. Rheumatology 2008; 1-8.
17. Leibrock J, Lottspeich F, Hohn A, Hofer M, Hengerer B, Masiakowski P, Thoenen H, Barde YA. Molecular cloning and expression of brain-derived neurotrophic factor. Nature 1989; 341: 149-52.
18. Leon A, Buriani A, Dal Toso R, Fabris M, Romanello S, Aloe L, Levi-Montalcini R. Mast cell synthesize,store and release nerve growth factor.Proc Natl Acad Sciences USA 1994; 91: 3739-43.
19. Levi-Montalcini R, Dal Toso R, della Valle F, Skaper SD, Leon A. Update of the NGF saga. J Neurol Sci 1995; 130: 119-27.
20. Lewin GR, Barde YA. Physiology of the Neurotrophins. Annu Rev Neurosci 1996; 19: 289-317.
21. Matucci-Cerinic M, Giacomelli R, Pignone A, Cagnoni ML, Generini S, Casale R, Cipriani P, Del Rosso A, Tirassa P, Konttinen YT, Kahaleh BM, Fan PS, Paoletti M, Marchesi C, Cagnoni M, Aloe L. Nerve growth factor and neuropeptides circulating levels in systemic sclerosis (scleroderma). Ann Rheum Dis 2001; 60: 487-94.
22. Milner P, Bodin P, Guiducci S, Del Rosso A, Kahaleh MB, Matucci-Cerinic M, Burnstock G. Regulation of substance P mRNA expression in human dermal microvascular endothelial cells. Clin Exp Rheumatol 2004; 22(Suppl 33): 24-7.
23. Murase K, Murakami Y, Takayanagi K, et al. Human fibroblast cells synthezise and secrete nerve growth factor. Biochem Biophys Res Commun 1992; 184: 373-9.
24. Nemoto K, Fukamachi K, Nemoto F, Miyata S, Hamada M, Nakamura Y, Senba E, Ueyama T. Gene Expression of Neurotrophins and their Receptors in Cultured Rat Vascular Smooth Muscle Cells. Biochem Biophys Res Commun 1998; 245: 284-8.
25. Nockher WA, Renz H. Neurotrophins in allergic diseases: From neuronal growth factors to intercellular signalling molecules. J Allergy Clin Immunol 2006; 117: 583-9.
26. Nonogaki K, Moser AH, Shigenaga J, Feingold KR,Grunfeld C. Beta-nerve growth factor as a mediator of the acute phase response in vivo. Biochem Biophys Res Commun 1996; 219: 956-61.
27. Rost B, Hanf G, Ohnemus U, Otto-Knapp R, Groneberg DA, Kunkel G, Noga O. Monocytes of allergics and non-allergics produce, store and release the neurotrophins NGF, BDNF and NT-3. Regul Pept 2005; 124: 19-25.
28. Santambrogio L, Benedetti M, Chao MV, Muzaffar R, Kulig K, Gabellini N, Hochwald G. Nerve growth factor production by lymphocytes. J Immunol 1994; 153: 4488-95.
29. Schmidt JA, Caspary I, von Bierbrauer A, Ehrly AM, Jünger M, Jung F, Lawall H. Standardisierung der Nagelfalz-Kapillarmikroskopie in der Routinediagnostik. VASA 1997; 26: 5-10.
30. Scott J, Selby M, Urdea M, Quiroga M, Bell GI, Rutter WJ. Isolation and nucleotide sequence of a cDNA encoding the precursor of mouse nerve growth factor.Nature 1983; 302: 538-40.
31. Skaper SD. Nerve Growth Factor. A neurocine orchestrating neuroimmuneendocrine functions. Mol Neurobiol 2001; 24: 183-99.
32. Stanisz AM, Stanisz JA. Nerve growth factor and neuroimmune interactions in inflammatory diseases. Ann N Y Acad Sci 2000; 917: 268-72.
33. Tuveri MA, Passiu G, Mathieu A, et al. Nerve growth factor and mast cell distribution in the skin of patients with systemic sclerosis. Clin Exp Rheumatol 1993; 11: 319-22.
34. Weigel I, Klein-Weigel P, Kinzl J, Biebl W, Fraedrich G, Heidrich H. Psychiatrische Untersuchungen an Tyroler Patienten mit primärem Raynaud-Phenomen. Wien Med Wochenschr 2005; 155: 416-21.
35. Woolf CJ, Safieh-Garabedian B, Ma QP, Crilly P, Winter J. Nerve growth factor contributes to the generation of inflammatory sensory hypersensitivity Neuroscience 1994; 62: 327-31.
36. Yamamoto H, Gurney ME. Human Platelets Contain Brain-Derived Neurotrophic Factor. J Neurosci 1990; 10: 3469-78.