ENaC, renal sodium excretion and extracellular ATP

Purinergic Signalling

Volumn 5, Issue 4, 2009, Pages 481-489

  Wildman, Scott Sp ^a   Kang, Esther S K ^b   King, Brian F ^c  

^a ROYAL VETERINARY COLLEGE   (United Kingdom)

^b BABRAHAM INSTITUTE   (United Kingdom)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Amiloride sensitive currents; ATP; Blood pressure; Kidney; Nucleotide; P2X4 receptor; P2Y2 receptor

Indexed keywords

EID: 70949086602     PISSN: 15739538     EISSN: 15739546     Source Type: Journal    
DOI: 10.1007/s11302-009-9150-6     Document Type: Review

References (70)

1. + conductance is reduced by the cystic fibrosis transmembrane conductance regulator in normal but not in cystic fibrosis airways J Clin Invest 102 15 21 10.1172/JCI2729 1:CAS:528: DyaK1cXktlWhtr8%3D 9649552
2. + transport in airway epithelia FASAB J 20 545 546 1:CAS:528:DC%2BD28Xis12gsb0%3D
3. EM Schwiebert DP Wallace GM Braunstein SR King J Peti-Peterdi K Hanaoka WB Guggino LM Guay-Woodford PD Bell LP Sullivan JJ Grantham AL Taylor 2002 Autocrine extracellular purinergic signalling in epithelial cells derived from polycystic kidneys Am J Physiol Renal Physiol 282 4 F763 F775 1:CAS:528:DC%2BD38XivVemtrk%3D 11880338
4. Turner CM, Elliott JI, Tam FWK (2009) P2 receptors in renal pathophysiology. Pur Sig. doi: 10.1007/s11302-009-9153-3
5. AC Guyton 1991 Blood pressure control-special role of the kidneys and body fluids Science 252 1813 1816 10.1126/science.2063193 1:STN:280: DyaK3M3ovFWgtQ%3D%3D 2063193
6. H-P Ma C-F Chou S-P Wei DC Eaton 2007 Regulation of the epithelial sodium channel by phosphatidylinositides: experiments, implications, and speculations Pflügers Arch 455 169 80 10.1007/s00424-007-0294-3 1:CAS:528: DC%2BD2sXhtVeisLzK 17605040 (Pubitemid 47403987)
7. SS Wildman J Marks CM Turner L Yew-Booth CM Peppiatt-Wildman BF King DG Shirley W-H Wang RJ Unwin 2008 Sodium-dependent regulation of renal amiloride-sensitive currents by apical P2 receptors J Am Soc Nephrol 19 731 42 10.1681/ASN.2007040443 1:CAS:528:DC%2BD1cXkvFOhsbw%3D 18235098
8. + channel is made of three homologous subunits Nature 12 463 467 10.1038/367463a0 (Pubitemid 24046048)
9. BF King A Townsend-Nicholson 2003 Nucleotide and nucleoside receptors Tocris Reviews 23 1 11
10. D Firsov L Schild I Gautchi A-M Merillat E Schneeberger BC Rossier 1996 Cell surface expression of the epithelial Na channel and a mutant causing Liddle syndrome: a quantitative approach Proc Nat Acad Sci USA 93 15370 15375 10.1073/pnas.93.26.15370 1:CAS:528:DyaK2sXnsFel 8986818 (Pubitemid 27009607)
11. TR Kleyman EJ Cragoe 1988 Amiloride and its analogs as tools in the study of ion transport J Memb Biol 105 1 21 10.1007/BF01871102 1:CAS:528:DyaL1MXjvVKj (Pubitemid 18240714)
12. 2 receptor Br J Pharmacol 121 1445 1453 10.1038/sj.bjp.0701286 1:CAS:528:DyaK2sXlt1Wjtro%3D 9257926 (Pubitemid 27317559)
13. JA Schafer 2002 Abnormal regulation of ENaC: syndromes of salt retention and salt wasting by the collecting duct Am J Physiol Renal Physiol 283 F221 F235 1:CAS:528:DC%2BD38XmslShtL8%3D 12110505
14. + absorption by extracellular nucleotides in human normal and cystic fibrosis airways Am J Respir Cell Mol Biol 23 755 761 1:CAS:528:DC%2BD3cXptFSru7c%3D 11104728
15. + channel trafficking Endocrinology 146 5079 5085 10.1210/en.2005-0894 1:CAS:528:DC%2BD2MXht1Ogur%2FJ 16150899 (Pubitemid 41653020)
16. + channel (ENaC) by phosphatidylinositides Am J Physiol Renal Physiol 290 F949 F957 10.1152/ajprenal.00386.2005 1:CAS:528:DC%2BD28XkvFSlsr0%3D 16601296 (Pubitemid 43724893)
17. RJ Unwin MA Bailey G Burnstock 2003 Purinergic signalling along the renal tubule: current state of play News Physiol Sci 18 237 241 1:CAS:528: DC%2BD2cXltVSi 14614156
18. EM Schwiebert BK Kishore 2001 Extracellular nucleotide signalling along the renal epithelium Am J Physiol Renal Physiol 280 F945 F963 1:CAS:528:DC%2BD3MXksFClu7g%3D 11352834
19. E Schwiebert A Zsembery 2003 Extracellular ATP as a signalling molecule for epithelial cells Biochim et Biophys Acta 1615 7 32 10.1016/S0005-2736(03) 00210-4 1:CAS:528:DC%2BD3sXms1yrsbw%3D (Pubitemid 37013465)
20. ER Lazarowski RC Boucher TK Harden 2003 Mechanisms of release of nucleotides and integration of their action as P2X- and P2Y- receptor activating molecules Mol Pharmacol 64 785 795 10.1124/mol.64.4.785 1:CAS:528: DC%2BD3sXnslGrtbk%3D 14500734 (Pubitemid 37153046)
21. H Praetorius J Frokiaer J Leipziger 2005 Transepithelial pressure pulses induce nucleotide release in polarized MDCK cells Am J Physiol Renal Physiol 288 F133 F141 10.1152/ajprenal.00238.2004 1:CAS:528:DC%2BD2MXhtVGjsbo%3D 15367389 (Pubitemid 40038685)
22. Praetorius HA, Leipziger J (2009) ATP release from non-excitable cells. Pur Sig. doi: 10.1007/s11302-009-9146-2
23. HF Cantiello 2001 Electrodiffusional ATP movement through CFTR and other ABC transporters Pflügers Arch 443 S22 S27 10.1007/s004240100639 1:CAS:528:DC%2BD3MXoslSmtrc%3D 11845298 (Pubitemid 33086947)
24. L Bahima J Aleu M Elias M Martin-Satue A Muhaisen J Blasi J Marsal J Solsona 2006 Endogenous hemichannels play a role in the release of ATP from Xenopus oocytes J Cell Physiol 206 95 102 10.1002/jcp.20440 1:CAS:528: DC%2BD2MXht12gsL3F 15965959 (Pubitemid 41740721)
25. PD Bell JY Lapointe R Sabirov S Hayashi J Peti-Peterdi K Manabe G Kovacs Y Okada 2003 Macula densa cell signalling involves ATP release through a maxi anion channel PNAS 100 4322 4327 10.1073/pnas.0736323100 1:CAS:528: DC%2BD3sXivFWjsbo%3D 12655045 (Pubitemid 36418201)
26. RM Vekaria 2004 Vesicular storage and release of ATP in a rat proximal tubule cell line J Physiol 560P C17
27. A Taylor L Schwiebert J Smith C King J Jones E Sorscher E Schwiebert 1999 Epithelial P2X purinergic receptor channel expression and function J Clin Invest 104 875 884 10.1172/JCI7270 1:CAS:528:DyaK1MXmsVClsb4%3D 10510328
28. J Leipziger 2003 Control of epithelial transport via luminal P2 receptors Am J Physiol Renal Physiol 284 F419 F432 1:CAS:528:DC%2BD3sXisFemsL8%3D 12556361
29. CM Turner O Vonend C Chan G Burnstock RJ Unwin 2003 The pattern of distribution of selected ATP-sensitive P2 receptor subtypes in normal rat kidney: an immunohistochemistry study Cells Tissues Organs 175 105 117 10.1159/000073754 1:CAS:528:DC%2BD3sXpvFSlt78%3D 14605489 (Pubitemid 37409854)
30. 2+ signalling Am J Physiol 270 F53 F60 1:CAS:528:DyaK28XhtFams7k%3D 8769822
31. + absorption in M-1 mouse cortical collecting duct cells J Physiol 524 77 90 10.1111/j.1469-7793.2000.00077.x 1:CAS:528:DC%2BD3cXislKrtL8%3D 10747185
32. + absorption in isolated perfused mouse CCD J Am Soc Nephrol 13 10 18 1:CAS:528: DC%2BD38XltV2hsA%3D%3D 11752016
33. 2 receptor-mediated inhibition of amiloride-sensitive short circuit current in M-1 mouse cortical collecting duct cells J Membrane Biol 183 115 124 10.1007/s00232-001-0059-4 1:CAS:528:DC%2BD3MXntFWiu7o%3D (Pubitemid 32900463)
34. H-P Ma L Li Z-H Zhou DC Eaton DG Warnock 2002 ATP masks stretch activation of epithelial sodium channels in A6 distal nephron cells Am J Physiol Renal Physiol 282 F501 F505 1:CAS:528:DC%2BD38Xit1GgtLs%3D 11832432
35. 2 FASEB J 19 142 3 1:CAS:528:DC%2BD2MXitVGgsg%3D%3D 15504951
36. + and water reabsorption FASEB J 21 3717 3726 10.1096/fj.07-8807com 1:CAS:528:DC%2BD2sXht12jsbfJ 17575258 (Pubitemid 350075159)
37. D McCoy A Taylor B Kudlow K Karlson M Slattery L Schwiebert E Schwiebert B Stanton 1999 Nucleotides regulate NaCl transport in mIMCD-K2 cells via P2X and P2Y purinergic receptors Am J Physiol Renal Physiol 277 F552 F559 1:CAS:528:DyaK1MXntF2gt7o%3D
38. 5 receptor Mol Pharmacol 63 1407 1416 10.1124/mol.63.6.1407 1:CAS:528:DC%2BD3sXkt1Sgs7o%3D 12761352 (Pubitemid 36627237)
39. 2+ ions Brit J Pharmacol 140 1177 1186 10.1038/sj.bjp.0705544 1:CAS:528:DC%2BD2cXpvV2msw%3D%3D (Pubitemid 38117421)
40. + channels and P2X receptors J Am Soc Nephrol. 16 2586 2597 10.1681/ASN.2005020130 1:CAS:528:DC%2BD2MXhtFeisL3K 16000699
41. W Ma A Korngreen N Uzlaner Z Priel SD Silberberg 1999 Extracellular sodium regulates airway ciliary motility by inhibiting a P2X receptor Nature 400 894 897 10.1038/23743 1:CAS:528:DyaK1MXlslGrsLw%3D 10476971 (Pubitemid 29406728)
42. W Ma A Korngreen S Weil EB-T Cohen A Priel L Kuzin SD Silberberg 2006 Pore properties and pharmacological features of the P2X receptor channel in airway ciliated cells J Physiol 571 503 517 10.1113/jphysiol.2005.103408 1:CAS:528:DC%2BD28XktVCktbk%3D 16423852 (Pubitemid 43329544)
43. B Brodin R Nielsen 2000 Electrophysiological evidence for an ATP-gated ion channel in the principal cells of the frog skin epithelium Pflügers Arch 439 227 233 10.1007/s004240050933 1:CAS:528:DC%2BD3cXhslOltrc%3D 10650971 (Pubitemid 30056896)
44. PJ Jensik D Holbird MW Collard TC Cox 2001 Cloning and characterisation of a functional P2X receptor from larval bullfrog skin Am J Physiol Cell Physiol 281 C954 C962 1:CAS:528:DC%2BD3MXmvFCgu7o%3D 11502572
45. + channel activity in renal epithelia Am J Physiol Renal Physiol 292 F1734 F1740 10.1152/ajprenal.00382.2006 1:CAS:528:DC%2BD2sXmvF2kurY%3D 17356127
46. J Gorelik Y Zhang D Sanchez A Shevchuk G Frolenkov M Lab D Klenerman C Edwards Y Korchev 2005 Aldosterone acts via an ATP autocrine/paracrine system: the Edelman ATP hypothesis revisited PNAS 102 15000 15005 10.1073/pnas. 0507008102 1:CAS:528:DC%2BD2MXhtFGqtb7F 16230642 (Pubitemid 41513324)
47. - Pflügers Arch 430 936 944 10.1007/BF01837407 8594546
48. D Jans SP Srinivas E Waelkens A Segal E Lariviere J Simeals W Van Driessche 2002 Hypotonic treatment evokes biphasic ATP release across the basolateral membrane of cultured renal epithelia (A6) J Physiol 545 543 555 10.1113/jphysiol.2002.026641 1:CAS:528:DC%2BD3sXktFyitw%3D%3D 12456833 (Pubitemid 36004388)
49. DG Shirley MA Bailey RJ Unwin 2005 In vivo stimulation of apical P2 receptors in collecting ducts: evidence for inhibition of sodium reabsorption Am J Physiol Renal Physiol 288 F1243 F1248 10.1152/ajprenal.00152.2004 1:CAS:528:DC%2BD2MXlsVymt7s%3D 15687251 (Pubitemid 40677095)
50. Wildman SS, Shirley DG, King BF, Unwin RJ. Indirect evidence for regulation of sodium reabsorption in sodium-restricted rats by an ATP-gated heteromeric P2X receptor. J Physiol 2004: 560P PC11.
51. 4 receptors by extracellular pH and zinc Br J Pharmacol 126 762 768 10.1038/sj.bjp.0702325 1:CAS:528:DyaK1MXhslWitL0%3D 10188989 (Pubitemid 29087857)
52. D Holbird P Jensik T Cox 2001 Aldosterone upregulates purinergic responses in larval amphibian skin epithelium J Comp Physiol 171 413 420 1:CAS:528:DC%2BD3MXlslWgtrg%3D
53. Nicke A, King BF (2006) Heteromerization of P2X receptors. In: Arias HR (ed) Biological and biophysical aspects of ligand-gated ion channel receptor superfamilies, Ch 15. Research SignPost, India, pp 383-417
54. M Schnizler M Buss W Clauss 2002 Effects of extracellular purines on ion transport across the integument of Hirudo medicinalis J Exp Biol 205 2705 13 1:CAS:528:DC%2BD38XnvVWjsL4%3D 12151376
55. AN Poulsen TL Klausen PS Pedersen NJ Willumsen O Frederiksen 2005 Regulation of ion transport via apical purinergic receptors in intact rabbit airway epithelium Pflügers Arch 450 227 35 10.1007/s00424-005-1388-4 1:CAS:528:DC%2BD2MXmtVSnsr8%3D 15822001 (Pubitemid 40966576)
56. + absorption in wild-type and & utriF508 CFTR-expressing human bronchial epithelia Am J Physiol Cell Physiol 45 C827 C837
57. + channels by CFTR and purinergic stimulation Kid Int 60 455 461 10.1046/j.1523-1755.2001.060002455.x 1:CAS:528:DC%2BD3MXmtVOns7k%3D (Pubitemid 32678888)
58. + absorption by extracellular nucleotides in mouse trachea Pflügers Arch 444 220 226 10.1007/s00424-002-0796-y 1:CAS:528:DC%2BD38XjtFyltL8%3D 11976935 (Pubitemid 34499264)
59. J König R Schreiber M Mall K Kunzelmann 2002 No evidence for inhibition of ENaC through CFTR-mediated release of ATP Biochim Biophys Acta 1565 17 28 10.1016/S0005-2736(02)00502-3 12225848 (Pubitemid 35239828)
60. + transport in epithelia and Xenopus oocytes J Membrane Biol 192 101 110 10.1007/s00232-002-1067-8 1:CAS:528:DC%2BD3sXjt1SltLo%3D (Pubitemid 37011500)
61. S Inglis R Olver S Wilson 2000 Differential effects of UTP and ATP on ion transport in porcine tracheal epithelium Brit J Pharmacol 130 367 374 10.1038/sj.bjp.0703324 1:CAS:528:DC%2BD3cXjsl2murk%3D
62. + absorption in rabbit tracheal epithelium Resp Physiol 107 173 180 10.1016/S0034-5687(96)02516-9 1:CAS:528:DyaK2sXis1Sitr0%3D (Pubitemid 27173340)
63. + absorption in distal bronchi Pflügers Arch 438 621 627 10.1007/s004240051085 1:CAS:528:DyaK1MXns1yltrc%3D 10555558 (Pubitemid 29454976)
64. IC Davis WM Sullender JM Hickman-Davis JR Lindsey S Matalon 2004 Nucleotide-mediated inhibition of alveolar fluid clearance in BALB/c mice after respiratory syncytial virus infection Am J Physiol Lung Cell Mol Physiol 286 L112 20 10.1152/ajplung.00218.2003 1:CAS:528:DC%2BD2cXot1ajsg%3D%3D 12948936
65. M Fronius A Berk W Clauss M Schnizler 2004 Ion transport across Xenopus alveolar epithelium is regulated by extracellular ATP, UTP and adenosine Resp Physiol Neurobiol 139 133 144 10.1016/j.resp.2003.09.007 1:CAS:528: DC%2BD2cXhslequrs%3D (Pubitemid 38281117)
66. 2 receptor-mediated inhibition of ion transport in distal lung epithelial cells Br J Pharmacol 128 293 300 10.1038/sj.bjp.0702767 1:CAS:528:DyaK1MXmsFWgsr4%3D 10510438 (Pubitemid 29458587)
67. 2 receptors Pflügers Arch 454 977 987 10.1007/s00424-007-0248-9 1:CAS:528:DC%2BD2sXpslarsr8%3D 17356885 (Pubitemid 47338455)
68. + absorption in guinea pig distal colon Am J Physiol Gastrointest Liver Physiol 283 G300 G308 1:CAS:528:DC%2BD38XmslSgtr8%3D 12121876
69. 2+-dependent mechanism Biol Reprod 63 1918 1924 10.1095/biolreprod63. 6.1918 1:CAS:528:DC%2BD3cXosVKhtbg%3D 11090466
70. J Bourke K Abel G Huxham V Cooper S Manley 1999 UTP-preferring P2 receptor mediates inhibition of sodium transport in porcine thyroid epithelial cells Br J Pharmacol 127 1787 92 10.1038/sj.bjp.0702733 1:CAS:528: DyaK1MXmtVarsbk%3D 10482908 (Pubitemid 29392872)