Relationship between blood alcohol concentration on admission and outcome in dimethoate organophosphorus self-poisoning

British Journal of Clinical Pharmacology

Volumn 68, Issue 6, 2009, Pages 916-919

  Eddleston, Michael ^a,b,e   Gunnell, David ^b,c   Von Meyer, Ludwig ^d   Eyer, Peter ^b,d  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b South Asian Clinical Toxicology Research Collaboration   (Sri Lanka)

^c UNIVERSITY OF BRISTOL   (United Kingdom)

^d UNIVERSITY OF MUNICH   (Germany)

^e QMRI E315   (United Kingdom)

Author keywords

Ethanol; Insecticide; Metabolism; Organophosphorus; Poisoning; Suicide

Indexed keywords

ALCOHOL; DIMETHOATE;

ADULT; ALCOHOL BLOOD LEVEL; ALCOHOL CONSUMPTION; ALCOHOL INTOXICATION; ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; SELF POISONING;

ADULT; DEVELOPING COUNTRIES; DRUG INTERACTIONS; ETHANOL; FEMALE; HUMANS; INSECTICIDES; MALE; ODDS RATIO; ORGANOPHOSPHORUS COMPOUNDS; SELF-INJURIOUS BEHAVIOR; SRI LANKA;

EID: 70849119236     PISSN: 03065251     EISSN: 13652125     Source Type: Journal    
DOI: 10.1111/j.1365-2125.2009.03533.x     Document Type: Article

References (15)

1. Jeyaratnam J. Acute pesticide poisoning: a major global health problem. World Health Stat Q 1990 43 : 139 44.
2. Gunnell D, Eddleston M, Phillips MR, Konradsen F. The global distribution of fatal pesticide self-poisoning: systematic review. BMC Public Health 2007 7 : 357.
3. Eddleston M. Patterns and problems of deliberate self-poisoning in the developing world. Q J Med 2000 93 : 715 31.
4. Eddleston M, Buckley NA, Eyer P, Dawson AH. Medical management of acute organophosphorus pesticide poisoning. Lancet 2008 371 : 597 607. (Pubitemid 351232010)
5. van der Hoek W, Konradsen F. Risk factors for acute pesticide poisoning in Sri Lanka. Trop Med Int Health 2005 10 : 589 96.
6. Abeyasinghe R, Gunnell D. Psychological autopsy study of suicide in three rural and semi-rural districts of Sri Lanka. Soc Psychiatry Psychiatr Epidemiol 2008 43 : 280 5.
7. Samaraweera S, Sumathipala A, Siribaddana S, Sivayogan S, Bhugra D. Completed suicide among Sinhalese in Sri Lanka: a psychological autopsy study. Suicide Life Threat Behav 2008 38 : 221 8.
8. Vijayakumar L. Suicide and its prevention: the urgent need in India. Indian J Psychiatry 2007 49 : 81 4.
9. Moss M, Burnham EL. Alcohol abuse in the critically ill patient. Lancet 2006 368 : 2231 42.
10. Eddleston M, Eyer P, Worek F, Sheriff MHR, Buckley NA. Predicting outcome using butyrylcholinesterase activity in organophosphorus pesticide self-poisoning. Q J Med 2008 101 : 467 74.
11. Eddleston M, Juszczak E, Buckley NA, Senarathna L, Mohammed F, Dissanayake W, Hittarage A, Azher S, Jeganathan J, Jayamanne S, Sheriff MHR, Warrell DA for the Ox-Col Poisoning Study collaborators. Multiple-dose activated charcoal in acute self-poisoning: a randomised controlled trial. Lancet 2008 371 : 579 86.
12. Eddleston M, Eyer P, Worek F, Mohamed F, Senarathna L, von Meyer L, Juszczak E, Hittarage A, Azher S, Dissanayake W, Sheriff MHR, Szinicz L, Dawson AH, Buckley NA. Differences between organophosphorus insecticides in human self-poisoning: a prospective cohort study. Lancet 2005 366 : 1452 9.
13. Worek F, Mast U, Kiderlen D, Diepold C, Eyer P. Improved determination of acetylcholinesterase activity in human whole blood. Clin Chim Acta 1999 288 : 73 90.
14. Buratti FM, Testai E. Evidences for CYP3A4 autoactivation in the desulfuration of dimethoate by the human liver. Toxicology 2007 241 : 33 46.
15. Jang GR, Harris RZ. Drug interactions involving ethanol and alcoholic beverages. Expert Opin Drug Metab Toxicol 2007 3 : 719 31.