Determinism and divergence of apoptosis susceptibility in mammalian cells

Journal of Cell Science

Volumn 122, Issue 23, 2009, Pages 4296-4302

  Bhola, Patrick D ^a   Simon, Sanford M ^a  

^a ROCKEFELLER UNIVERSITY   (United States)

Author keywords

Caspase; Epigenetics; Fluorescence microscopy; Lineage; Protease

Indexed keywords

CASPASE; CYSTEINE PROTEINASE; PEPTIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; CELL FATE; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME ASSAY; FLUORESCENCE MICROSCOPY; GENETIC DISTANCE; GENETIC SIMILARITY; HELA CELL; HUMAN; HUMAN CELL; NONHUMAN; PHYLOGENY; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN SYNTHESIS INHIBITION;

ANIMALS; APOPTOSIS; CASPASES; CELL LINE; CELLS; EPIGENESIS, GENETIC; HELA CELLS; HUMANS; MICE; MICROSCOPY, FLUORESCENCE; NIH 3T3 CELLS; SIGNAL TRANSDUCTION;

MAMMALIA;

EID: 70849090419     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: 10.1242/jcs.055590     Document Type: Article

References (28)

1. Abkowitz, J. L., Catlin, S. N. and Guttorp, P. (1996). Evidence that hematopoiesis may be a stochastic process in vivo. Nat. Med. 2, 190-197.
2. Albeck, J. G., Burke, J. M., Aldridge, B. B., Zhang, M., Lauffenburger, D. A. and Sorger, P. K. (2008). Quantitative analysis of pathways controlling extrinsic apoptosis in single cells. Mol. Cell 30, 11-25.
3. Arkin, A., Ross, J. and McAdams, H. H. (1998). Stochastic kinetic analysis of developmental pathway bifurcation in phage lambda-infected Escherichia coli cells. Genetics 149, 1633-1648.
4. Cohen, A. A., Geva-Zatorsky, N., Eden, E., Frenkel-Morgenstern, M., Issaeva, I., Sigal, A., Milo, R., Cohen-Saidon, C., Liron, Y., Kam, Z. et al. (2008). Dynamic proteomics of individual cancer cells in response to a drug. Science 322, 1511-1516.
5. Danial, N. N. and Korsmeyer, S. J. (2004). Cell death: critical control points. Cell 116, 205-219.
6. Ellis, R. E., Yuan, J. Y. and Horvitz, H. R. (1991). Mechanisms and functions of cell death. Annu. Rev. Cell Biol. 7, 663-698.
7. Ennis, H. L. and Lubin, M. (1964). Cycloheximide: Aspects of inhibition of protein synthesis in mammalian cells. Science 146, 1474-1476.
8. Enver, T., Heyworth, C. M. and Dexter, T. M. (1998). Do stem cells play dice? Blood 92, 348-351.
9. Goldstein, J. C., Waterhouse, N. J., Juin, P., Evan, G. I. and Green, D. R. (2000). The coordinate release of cytochrome c during apoptosis is rapid, complete and kinetically invariant. Nat. Cell Biol. 2, 156-162.
10. Liu, X., Zou, H., Slaughter, C. and Wang, X. (1997). DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis. Cell 89, 175-184.
11. Nguyen, A. W. and Daugherty, P. S. (2005). Evolutionary optimization of fluorescent proteins for intracellular FRET. Nat. Biotechnol. 23, 355-360.
12. Ow, Y. L., Green, D. R., Hao, Z. and Mak, T. W. (2008). Cytochrome c: functions beyond respiration. Nat. Rev. Mol. Cell. Biol. 9, 532-542.
13. Rehm, M., Dussmann, H. and Prehn, J. H. (2003). Real-time single cell analysis of Smac/DIABLO release during apoptosis. J. Cell Biol. 162, 1031-1043.
14. Rizzo, M. A., Springer, G. H., Granada, B. and Piston, D. W. (2004). An improved cyan fluorescent protein variant useful for FRET. Nat. Biotechnol. 22, 445-449.
15. Salvesen, G. S. and Dixit, V. M. (1997). Caspases: intracellular signaling by proteolysis. Cell 91, 443-446.
16. Schotte, P., Declercq, W., Van Huffel, S., Vandenabeele, P. and Beyaert, R. (1999). Non-specific effects of methyl ketone peptide inhibitors of caspases. FEBS Lett. 442, 117-121.
17. Shaner, N. C., Campbell, R. E., Steinbach, P. A., Giepmans, B. N., Palmer, A. E. and Tsien, R. Y. (2004). Improved monomeric red, orange and yellow fluorescent proteins derived from Discosoma sp. red fluorescent protein. Nat. Biotechnol. 22, 1567-1572.
18. Sheridan, C. and Martin, S. J. (2008). Commitment in apoptosis: slightly dead but mostly alive. Trends Cell Biol. 18, 353-357.
19. Siegel, M. R. and Sisler, H. D. (1963). Inhibition of protein synthesis in vitro by cycloheximide. Nature (London) 200, 675-676.
20. Sigal, A., Milo, R., Cohen, A., Geva-Zatorsky, N., Klein, Y., Liron, Y., Rosenfeld, N., Danon, T., Perzov, N. and Alon, U. (2006). Variability and memory of protein levels in human cells. Nature (London) 444, 643-646.
21. Skene, J. H. and Virag, I. (1989). Posttranslational membrane attachment and dynamic fatty acylation of a neuronal growth cone protein, GAP-43. J. Cell Biol. 108, 613-624.
22. Spudich, J. L. and Koshland, D. E., Jr (1976). Non-genetic individuality: chance in the single cell. Nature (London) 262, 467-471.
23. Thornberry, N. A., Rano, T. A., Peterson, E. P., Rasper, D. M., Timkey, T., Garcia-Calvo, M., Houtzager, V. M., Nordstrom, P. A., Roy, S., Vaillancourt, J. P. et al. (1997). A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis. J Biol. Chem. 272, 17907-17911.
24. Traut, R. R. and Monro, R. E. (1964). The puromycin reaction and its relation to protein synthesis. J. Mol. Biol. 10, 63-72.
25. Weinberger, L. S., Burnett, J. C., Toettcher, J. E., Arkin, A. P. and Schaffer, D. V. (2005). Stochastic gene expression in a lentiviral positive-feedback loop: HIV-1 Tat fluctuations drive phenotypic diversity. Cell 122, 169-182.
26. Wyllie, A. H. (1980). Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation. Nature (London) 284, 555-556.
27. Xu, F., Carlos, T., Li, M., Sanchez-Sweatman, O., Khokha, R. and Gorelik, E. (1998). Inhibition of VLA-4 and up-regulation of TIMP-1 expression in B16BL6 melanoma cells transfected with MHC class I genes. Clin. Exp. Metastasis 16, 358-370.
28. Yuan, J., Shaham, S., Ledoux, S., Ellis, H. M. and Horvitz, H. R. (1993). The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1 betaconverting enzyme. Cell 75, 641-652.