Transcripts of caicium/caimodulin-dependent kinases are changed after forskolin- or ibmx-induced insulin secretion due to melatonin treatment of rat insulinoma β-cells (INS-1)

Hormone and Metabolic Research

Volumn 41, Issue 11, 2009, Pages 805-813

  Bazwinsky Wutschke, I ^a   Muhlbauer E ^b   Wolgast S ^b   Peschke, E ^a  

^a MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

^b Saxon Academy of Sciences   (Germany)

Author keywords

Calcium; Calmodulin Dependent kinase 2d; Calmodulin dependent kinase iv; Insulin secretion; Pancreatic islet

Indexed keywords

CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE 2D; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE IV; FORSKOLIN; INSULIN; ISOBUTYLMETHYLXANTHINE; ISOPROTEIN; LUZINDOLE; MELATONIN; UNCLASSIFIED DRUG; CALCIUM;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DISEASE MODEL; DOWN REGULATION; DRUG EFFECT; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; INSULIN RELEASE; INSULINOMA; NONHUMAN; NUCLEOTIDE SEQUENCE; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; ANIMAL; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PANCREAS ISLET; SECRETION; TUMOR CELL LINE; WISTAR RAT;

RATTUS;

1-METHYL-3-ISOBUTYLXANTHINE; ANIMALS; CALCIUM; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASES; CELL LINE, TUMOR; FORSKOLIN; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HUMANS; INSULIN; INSULIN-SECRETING CELLS; INSULINOMA; ISLETS OF LANGERHANS; MELATONIN; RATS; RATS, WISTAR;

EID: 70649114665     PISSN: 00185043     EISSN: 14394286     Source Type: Journal    
DOI: 10.1055/s-0029-1225631     Document Type: Article

References (62)

1. Jones PM, Persaud SJ. Protein kinases, protein phosphorylation, and the regulation of insulin secretion from pancreatic β-cells. Endocr Rev 1998; 19: 429-461 (Pubitemid 29116376)
2. HenquinJC, Ravier MA, Nenquin M, Jonas JC, Gilon P. Hierarchy of the beta-cell signals controlling insulin secretion. Eur J Clin Invest 2003; 33: 742-750 (Pubitemid 37082859)
3. Cromada J, Brock B, Schmitz O, Rorsman P. Glucagon-like peptide-1 : regulation of insulin secretion and therapeutic potential. Basic Clin Pharmacol Toxicol 2004; 95: 252-262 (Pubitemid 39657642)
4. Taskén K, Aandahl EM. Localized effects of cAMP mediated by distinct routes of protein kinase A. Physiol Rev 2004; 84:137-167 (Pubitemid 38049878)
5. Dyachok O, SagetorpJ, Isakov Y, Tertgholm A. cAMP oscillations restrict protein kinase A redistribution in insulin-secreting cells. Biochem Soc Trans 2006; 34: 498-501 (Pubitemid 44230746)
6. Dyachok O, Isakov Y, Sagetorp J, Tengholm A. Oscillations of cyclic AMP in hormone-stimulated insulin-secreting beta-cells. Nature 2006; 439: 349-352
7. 2+-operated transcriptional networks: molecular mechanisms and in vivo models. Physiol Rev 2008; 88: 421-449
8. Eckert B, Schwaninger M, Knepel W. Calcium-mobilizing insulin secre-tagogues stimulate transcription that is directed by the cyclic adenosine 3′,5′-monophosphate/calcium response element in a pancreatic islet beta-cell line. Endocrinology 1996; 137: 225-233 (Pubitemid 126424578)
9. Ban N, Yamada Y, Someya Y, Ihara Y, Adachi T, Kubota A, Watanabe R, KuroeA, da A, Miyawaki K, Sunaga Y, Shen ZP, Iwakura T, Tsukiyama K, Toyokuni S, Tsuda K, Seino Y. Activating transcription factor-2 is a positive regulator in CaM kinase IV-induced human insulin gene expression. Diabetes 2000; 49:1142-1148
10. Andrali SS, Sampley ML, Wanderford NL, Ozean S. Glucose regulation of insulin gene expression in pancreatic beta-cells. Biochem J 2008; 415: 1-10
11. 2+-receptors in the pancreatic beta-cell in insulin secretion. MoI Cell Biochem 1999; 190: 119-124
12. 2+/calmodulin-dependent protein kinase II and synapsin I-like protein in mouse insulinoma MIN6 cells. Endocrinology 1995; 136: 3784-3793
13. Easom RA. CaM kinase II: a protein kinase with extraordinary talents germane to insulin exocytosis. Diabetes 1999; 48: 675-684
14. Yu X, Murao K, Sayo Y, Imachi H, Cao WM, Ohtsuka S, NIM M, Tu H, nuzuka H, Wong NC, Kobayashi R, Ishida T. The role of calcium/calmodulin-dependent protein kinase cascade in glucose up-regulation of insulin gene expression. Diabetes 2004; 53:1475-1481
15. Peschke E, Peschke D. Evidence for a circadian rhythm of insulin release from perifused rat pancreatic islets. Diabetologia 1998; 41:1085-1092 (Pubitemid 28394415)
16. Peschke E. Melatonin, endocrine pancreas and diabetes. J Pineal Res 2008; 44: 26-40
17. Peschke E, Mühlbauer E, Musshoff U, Csernus VJ, Chankiewitz E, Peschke D. Receptor MTl mediated influence of melat onin on cAMP concentration and insulin secretion of rat insulinoma cells INS-I. J Pineal Res 2002; 33: 63-71
18. Peschke E, Peschke D, Hammer T, Csernus VJ. Influence of melatonin and serotonin on glucose-stimulated insulin release from perifused rat pancreatic islets in vitro. J Pineal Res 1997; 23: 156-163 (Pubitemid 127500008)
19. Peschke E, Fauteck JD, Musshoff U, Schmidt F, Beckmann A, Peschke D. Evidence for a melatonin receptor within pancreatic islets of neonate rats: functional, autoradiographic, and molecular investigations. J Pineal Res 2000; 28: 156-164 (Pubitemid 30162447)
20. Peschke E, Bach AC, Mühlbauer E. Parallel signaling pathways of melatonin in the pancreatic beta-cell. J Pineal Res 2006; 40:184-191
21. Laychock SC. Impaired cyclic AMP response to stimuli in glucose-desensitized rat pancreatic islets. MoI Cell Endocrinology 1995; 113:19-28
22. Stumpf I, Mühlbauer E, Peschke E. Involvement of the cGMP pathway in mediating the insulin-inhibitory effect of melatonin in pancreatic beta-cells. J Pineal Res 2008; 45: 318-327
23. Mühlbauer E, Peschke E. Evidence for the expression of both the MTland in addition, the MT2-melatonin receptor, in the rat pancreas, islet and beta-cell. J Pineal Res 2007; 42:105-106 (Pubitemid 44924332)
24. Peschke E, Stumpf I, Bazwinsky I, Litvak L, Dralle H, Mühlbauer E. Melatonin and type 2 diabetes - a possible link? J Pineal Res 2007; 42: 350-358
25. Csernus VJ, Hammer T, Peschke D, Peschke E. Dynamic insulin secretion from perifused rat pancreatic islets. Cell Mol Life Sci 1998; 54: 733-743
26. Mühlbauer E, Wolgast S, finckh U, Peschke D, Peschke E. Indication of circadian oscillations in the rat pancreas. FEBS Lett 2004; 564: 91-96
27. Pfqffl MW, Horgan GW, Dempfle L Relative expression software tool (REST) for group-wise comparison and statistical analysis of relative expression results in real-time PCR. Nucleic Acids Res 2002; 30: e36
28. 2+ release from INS-I insulinoma cells. J Pineal Res 2005; 39: 316-323
29. Mühlbauer E, Bazwinsky I, Wolgast S, Klemenz A, Peschke E. Orcadian changes of ether-a-go-go-related-gene (Erg) potassium channel transcripts in the rat pancreas and beta-cell. Cell Mol Life Sei 2007; 64: 768-780
30. Shafer SH, Phelps SH, Williams A. Reduced DNA synthesis and cell viabil-ity in small cell lung carcinoma by treatment with cyclic AMP phosphodiesterase inhibitors. Biochem Pharmacol 1998; 56:1229-1236
31. HanouneJ, Defer N. Regulation and role of adenylyl cyclase isoforms. Annu Rev Pharmacol Toxicol 2001; 41:145-174 (Pubitemid 32385886)
32. Kemp DM, Ubeda M, Habener JF. Identification and functional characterization of melatonin Mella receptors in pancreatic beta cells: potential role in incretin-mediated cell function by sensitization of cAMP signaling. MoI Cell Endocrinol 2002; 191:157-166 (Pubitemid 34626621)
33. Godson C, Reppert SM. The Mella melatonin receptor is coupled to parallel signal transduction pathways. Endocrinology 1997; 138: 397-404 (Pubitemid 27009449)
34. Witt-Enderby PA, Masana Ml, Dubocovich ML. Physiological exposure to melatonin supersensitizes the cyclic adenosine 3′,5′-monophosphate- dependent signal transduction cascade in Chinese hamster ovary cells expressing the human mtl melatonin receptor. Endocrinology 1998; 139: 3064-3071 (Pubitemid 28512332)
35. Picinato MC, Haber EP, Cipolla-Neto J, Curi R, de Oliveira Carvalho CR, Carpinelli AR, Melatonin inhibits insulin secretion and decreases PICA levels without interfering with glucose metabolism in rat pancreatic islets. J Pineal Res 2002; 33:156-160
36. Usachev Y, Verkhratsky A. IBMX induces calcium release from intracellular stores in rat sensory neurones. Cell Calcium 1995; 17:197-206
37. 2+]In. Pflugers Arch 1995; 430: 420-428
38. Dolphin AC, Forda SR, Scott RH. Calcium-dependent currents in cultured rat dorsal root ganglion neurones are inhibited by an adenosine analogue. J Physiol 1986; 373:47-61 (Pubitemid 16078299)
39. Choi OH, Shamim MT, Padgett WL, Daly JW. Caffeine and theophylline analogues: correlation of behavioral effects with activity as adenosine receptor antagonists and as phosphodiesterase inhibitors. Life Sci 1988; 43:387-398
40. 2+ channel alpha1C subunits by 3-isobutyl-1 -methylxanthine. Eur J Pharmacol 1998 ; 342 : 353-358
41. Jockers R, Maurice P, Boutin JA, Delagrange P. Melatonin receptors, heterodimerization, signal transduction and binding sites: what's new? Br J Pharmacol 2008; 154:1182-1195 (Pubitemid 351992057)
42. Dubocovich ML, Yun K, Al-Ghoul WM, Benloucif S, Masana ML Selective MT2 melatonin receptor antagonists block melatonin-mediated phase advances of circadian rhythms. FASEB J 1998; 12:1211-1220 (Pubitemid 28418951)
43. Browning C, Beresford I, Fraser N, Giles H. Pharmacological characterization of human recombinant melatonin MT(I) and MT(2) receptors. Br J Pharmacol 2000; 129: 877-886
44. Ayoub MA, LevoyeA, Delagrang EP, Jockers R. Preferential formation of MTl/MT2 melatonin receptor heterodimers with distinct ligand interaction properties compared with MT2 homodimers. Mol Pharmacol 2004; 66: 312-321
45. 2+-dependent activation of phospholipase C in insulin-secreting cells. J Biol Chem 2006; 281: 28499-28507
46. 2+] oscillations in mouse pancreatic islets by adrenergic agonists. Biochem Biophys Res Commun 2007; 363: 1038-1043
47. Chaloux B, Caron AZ, Cuillemette G. Protein kinase A increases the binding affinity and the Ca2+ release activity of the inositol 1,4,5-trisphosphate receptor type 3 in RINm5F cells. Biol Cell 2007; 99: 379-388
48. 2+ and cAMP signaling in the insulin-secreting MIN6 beta-cell line. J Biol Chem 2005; 280: 31294-31302
49. Slanar O, Pelisek V, Vanecek J. Melatonin inhibits pituitary adenylyl cyclase-activating polypeptide-induced increase in cyclic AMP accumulation and [Ca2+Ji in cultured cells of neonatal rat pituitary. Neurochem Int 2000; 36: 213-219
50. Vanecek J. Inhibitory effect of melatonin on GnRH-induced LH release. Rev Reprod 1999; 4: 67-72 (Pubitemid 29245930)
51. Dai J, Inscho EW, Yuan L, Hill SM. Modulation of intracellular calcium and calmodulin by melatonin in MCF-7 human breast cancer cells. J Pineal Res 2002; 32:112-119 (Pubitemid 34289589)
52. Schuster C, Williams LM, Morris A, Morgan PJ, Barrett P. The human MTl melatonin receptor stimulates cAMP production in the human neuroblastoma cell line SH-SY5Y cells via a calcium-calmodulin signal transduction pathway. J Neuroendocrinol 2005; 1:170-178 (Pubitemid 40553016)
53. 2+ calmodulin-dependent kinase II activity by melatonin. Biochim Biophys Acta 1996; 1290:191-196
54. 2+/calmodulin-dependent protein kinase II-dependent long-term potentiation in the rat suprachiasmatic nucleus and its inhibition by melatonin. J Neurosci Res 2002; 70: 799-807
55. Daniel PB, Walker WH, Habener JF. Cyclic AMP signaling and gene regulation. Ann Rev Nutr 1998; 18: 353-383
56. McNulty S, Ross AW, Barrett P, Hastings MH, Morgan PJ. Melatonin regulates the phosphorylation of CREB in ovine pars tuberalis. J Neuroendocrinol 1994; 6: 523-532 (Pubitemid 24315328)
57. McNulty S, RossAW, Shiu KY, Morgan PJ, Hastings MH. Phosphorylation of CREB in ovine pars tuberalis is regulated both by cyclic AMP dependent and cyclic AMP-independent mechanisms. J Neuroendocrinol 1996; 8: 635-645
58. McNulty S, Schurov IL, Sloper PJ, Hasting MH. Stimuli which entrain the circadian clock of the neonatal Syrian hamster in vivo regulate the phosphorylation of the transcription factor CREB in the supra-chiasmatic nucleus in vitro. Eur J Neurosci 1998; 10:1063-1072
59. von Gall C, Weaver DR, Kock M, Korf HW, Stehle JH. Melatonin limits transcriptional impact of phosphoCREB in the mouse SCN via the Mella receptor. Neuroreport 2000; 11: 1803-1807
60. Sheynzon P, Korf HW. Targeted deletions of Mella and Mel1b melatonin receptors affect pCREB levels in lactotroph and pars intermedia cells of mice. Neurosci Lett 2006; 407:48-52 (Pubitemid 44345009)
61. 2+/calmodulin-dependent protein kinase II in insulinoma MIN6 cells. Endocrinology 2000; 141: 2350-2360
62. 2+/calmodulin-dependent protein kinase II delta2 regulates gene expression of insulin in INS-1 rat insulinoma cells. Cell Calcium 2003; 33: 175-184