Visual function, optic nerve structure, and ocular blood flow parameters after 1 year of glaucoma treatment ith fixed combinations

European Journal of Ophthalmology

Volumn 19, Issue 5, 2009, Pages 790-797

  Januleviciene, Ingrida ^a   Ehrlich, Rita ^b   Siesky, Brent ^b   Nedzelskiené, Irena ^a   Harris, Alon ^b  

^a KAUNAS UNIVERSITY OF MEDICINE   (Lithuania)

^b INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Fixed combination treatment; Glaucoma; Ocular hemodynamics; Optic nerve structure; Visual function

Indexed keywords

DORZOLAMIDE PLUS TIMOLOL; LATANOPROST PLUS TIMOLOL;

ADULT; ARTERIAL PRESSURE; ARTICLE; CILIARY ARTERY; CLINICAL ARTICLE; CLINICAL TRIAL; COHORT ANALYSIS; COLOR ULTRASOUND FLOWMETRY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIASTOLIC PERFUSION; DOUBLE BLIND PROCEDURE; EYE DISEASE; FEMALE; HUMAN; INTRAOCULAR PRESSURE; MALE; NERVE FIBER; OCULAR BLOOD VESSEL; OCULAR PERFUSION; OPEN ANGLE GLAUCOMA; OPHTHALMIC ARTERY; OPTIC NERVE; POLARIMETRY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RETINA ARTERY; THICKNESS; TREATMENT DURATION; VISUAL FIELD;

ANTIHYPERTENSIVE AGENTS; BLOOD FLOW VELOCITY; BLOOD PRESSURE; CILIARY ARTERIES; DOUBLE-BLIND METHOD; DRUG COMBINATIONS; EYE; FEMALE; GLAUCOMA, OPEN-ANGLE; HUMANS; INTRAOCULAR PRESSURE; LASER-DOPPLER FLOWMETRY; MALE; MIDDLE AGED; NERVE FIBERS; OPHTHALMIC ARTERY; OPTIC NERVE; PROSPECTIVE STUDIES; PROSTAGLANDINS F, SYNTHETIC; REGIONAL BLOOD FLOW; RETINAL ARTERY; SULFONAMIDES; THIOPHENES; TIMOLOL; VISUAL ACUITY; VISUAL FIELDS;

EID: 70549109863     PISSN: 11206721     EISSN: None     Source Type: Journal    
DOI: 10.1177/112067210901900517     Document Type: Article

References (34)

1. Feke GT, Pasquale LR. Retinal blood flow response to posture change in glaucoma patients compared with healthy subjects. Ophthalmology 2008; 115: 246-52.
2. Leske MC, Heijl A, Hyman L, Bengtsson B, Dong L, Yang Z. EMGT Group. Predictors of long-term progression in the Early Manifest Glaucoma Trial. Ophthalmology 2007; 114: 1965-72.
3. The AGIS Investigators. The Advanced Glaucoma Intervention Study (AGIS). The relationship between control of intraocular pressure and visual field deterioration. Am J Ophthalmol 2000; 130: 429-40.
4. Flammer J, Orgül S, Costa VP. The impact of ocular blood flow in glaucoma. Prog Retin Eye Res 2002; 21: 359-93.
5. Liu X, Ge J, Zhou W, Lin Y, Cai X. Hemodynamics of ophthalmic artery and central retinal artery and correlation with other factors in patients with primary open angle glaucoma. Yan Ke Xue Bao 1998; 14: 138-44.
6. Satilmis M, Orgul S, Doubler B, Flammer J. Rate of progression of glaucoma correlates with retrobulbar circulation and intraocular pressure. Am J Ophthalmol 2003; 135: 664-9.
7. Harwerth RS, Quigley HA. Visual field defects and retinal ganglion cell losses in patients with glaucoma. Arch Ophthalmol 2006; 124: 853-85.
8. Keltner JL, Johnson CA, Quigg JM, Cello KE, Kass MA, Gordon MO, for the Ocular Hypertension Treatment Study Group. Confirmation of visual field abnormalities in the ocular hypertension treatment study. Arch Ophthalmol 2000; 118: 1187-94.
9. Osborne N, Melena J, Chidlow G, Wood JPM. A hypothesis to explain ganglion cell death caused by vascular insults at the optic nerve head: possible implication for the treatment of glaucoma. Br J Ophthalmol 2001; 85: 1252-9.
10. Sommer A, Katz J, Quigley HA, et al. Clinically detectable nerve fiber atrophy precedes the onset of glaucomatous field loss. Arch Ophthalmol 1991; 109: 77-83.
11. Tuulonen A, Airaksinen P. Initial glaucomatous optic disk and retinal nerve fiber layer abnormalities and their progression. Am J Ophthalmol 1991; 111: 485-90.
12. Woodward DF, Chen J. Fixed-combination and emerging glaucoma therapies. Exp Opin Emerg Drugs 2007; 12: 313-27.
13. Vorwerk C, Thelen U, Buchholz P, Kimmich F. Treatment of glaucoma patients with insufficient intraocular pressure control. Curr Med Res Opin 2008; 24: 1295-301.
14. European Glaucoma Society. Terminology and Guidelines for Glaucoma. III ed. Savona, Italy: Editrice DOGMA S.r.l., 2008; 93-111.
15. Sehi M, Flanagan JG, Zeng L, Cook RJ, Trope GE. Relative change in diurnal mean ocular perfusion pressure: a risk factor for the diagnosis of primary open-angle glaucoma. Invest Ophthalmol Vis Sci 2005; 46: 561-7.
16. Harris A, Arend O, Arend S, Martin B. Effects of topical dorzolamide on retinal and retrobulbar hemodynamics. Acta Ophthalmol Scand 1996; 74: 569-72.
17. Harris A, Arend O, Kagemann L, Garrett M, Chung HS, Martin B. Dorzolamide, visual function and ocular hemodynamics in normal-tension glaucoma. J Ocul Pharmacol Ther 1999; 15: 189-97.
18. Harris A, Arend O, Chung HS, Kageman L, Cantor L, Martin B. A comparative study of betaxolol and dorzolamide effect on ocular circulation in normal-tension glaucoma patients. Ophthalmology 2000; 107: 430-4.
19. Harris A, Jonescu-Cuypers CP, Kagemann L, et al. Effect of dorzolamide timolol combination versus timolol 0.5% on ocular blood flow in patients with primary open-angle glaucoma. Am J Ophthalmol 2001; 132: 490-5.
20. Martinez A, Gonzalez F, Capeans C, Perez R, Sanchez-Salorio M. Dorzolamide effect on ocular blood flow. Invest Ophthalmol Vis Sci 1999; 40: 1270-5.
21. Avunduk AM, Sari A, Akyol N, et al. The one-month effects of topical betaxolol, dorzolamide and apraclonidine on ocular blood flow velocities in patients with newly diagnosed primary open-angle glaucoma. Ophthalmologica 2001; 215: 361-5.
22. Bernd AS, Pillunat LE, Bohm AG, Schmidt KG, Richard G. Okuläre Hämodynamik und Gesichtsfeld beim Glaukom unter Dorzolamid-Therapie. Ophthalmologe 2001; 98: 451-5.
23. Grunwald JE, Mathur S, Dupont J. Effects of topical dorzolamide on retinal and retrobulbar hemodynamics. Acta Ophthalmol Scand 1S97; 75: 236-8.
24. Pillunat LE, Bohm AG, Koller AU, Schmidt KG, Klemm M, Richard G. Effect of topical dorzolamide on optic nerve head blood flow. Graefes Arch Clin Exp Ophthalmol 1999; 237: 495-500.
25. Bergstrand IC, Heijl A, Harris A. Dorzolamide and ocular blood flow in previously untreated glaucoma patients: a controlled double-masked study. Acta Ophthalmol Scand 2002; 80: 176-82.
26. Fuchsjäger-Mayrl G, Wally B, Georgopoulos M, et al. Ocular blood flow and systemic blood pressure in patients with primary open-angle glaucoma and ocular hypertension. Invest Ophthalmol Vis Sci 2004; 45: 834-9.
27. Choi J, Kim KH, Jeong J, Cho H, Lee CH, Kook MS. Circadian fluctuation of mean ocular perfusion pressure is a consistent risk factor for normal-tension glaucoma. Invest Ophthalmol Vis Sci 2007; 48: 104-11.
28. Siesky B, Harris A, Sines D, et al. A comparative analysis of the effects of the fixed combination of timolol and dorzolamide versus latanoprost plus timolol on ocular hemodynamics and visual function in patients with primary open-angle glaucoma. J Ocul Pharmacol Ther 2006; 22: 353-61.
29. Plange N, Kaup M, Arend O, Remky A. Asymmetric visual field loss and retrobulbar haemodynamics in primary open-angle glaucoma. Graefes Arch Clin Exp Ophthalmol 2006; 244: 978-83.
30. Zeitz O, Galambos P, Wagenfeld L, et al. Glaucoma progression is associated with decreased blood flow velocities in the short posterior ciliary artery. Br J Ophthalmol 2006; 90: 1245-8.
31. Galassi F, Sodi A, Ucci F, Renieri G, Pieri B, Baccini M. Ocular hemodynamics and glaucoma prognosis: a color Doppler imaging study. Arch Ophthalmol 2003; 121: 1711-5.
32. Plange N, Kaup M, Weber A, Arend KO, Remky A. Retrobulbar haemodynamics and morphometric optic disc analysis in primary open-angle glaucoma. Br J Ophthalmol 2006; 90: 1501-4.
33. Reus NJ, Lemij HG. Diagnostic accuracy of the GDxVCC for glaucoma. Ophthalmology 2004; 111: 1860-5.
34. Medeiros FA, Vizzeri G, Zangwill LM, Alencar LM, Sample PA, Weinreb RN. Comparison of retinal nerve fiber layer and optic disc imaging for diagnosing glaucoma in patients suspected of having the disease. Ophthalmology 2008; 115: 1340-6.