Establishment of liquid chromatography/mass spectrometry for determination of bicyclol in rat single-pass intestinal perfusion

Biomedical Chromatography

Volumn 23, Issue 10, 2009, Pages 1059-1063

  Tan, Wei ^a   Wang, Bao Lian ^a   Hu, Jin Ping ^a   Sheng, Li ^a   Li, Yan ^a  

^a INSTITUTE OF MATERIA MEDICA   (China)

Author keywords

Bicyclol; HPLC MS; Intestinal perfusion; Quantification

Indexed keywords

ELECTROSPRAY IONIZATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MASS SPECTROMETERS; MASS SPECTROMETRY; RATS;

BICYCLOL; HPLC-MS; INTESTINAL PERFUSION; LIQUID CHROMATOGRAPHY - MASS SPECTROMETRIES; QUANTIFICATION; RAPID METHOD; RAT PLASMA; SENSITIVE METHOD; SIMPLE METHOD; SINGLE PASS;

POSITIVE IONS;

ANTIVIRUS AGENT; BICYCLOL; BIPHENYLDICARBOXYLATE; CARBOXYLIC ACID; METHANOL; SODIUM; UNCLASSIFIED DRUG; WATER;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CALIBRATION; CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG PENETRATION; DRUG TISSUE LEVEL; ELECTROSPRAY MASS SPECTROMETRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INTESTINE PERFUSION; ION TRAP MASS SPECTROMETRY; LIQUID LIQUID EXTRACTION; MALE; MESENTERIC VEIN; NONHUMAN; PHASE SEPARATION; RAT; REACTION TIME; SENSITIVITY AND SPECIFICITY;

RATTUS;

EID: 70549101163     PISSN: 02693879     EISSN: 10990801     Source Type: Journal    
DOI: 10.1002/bmc.1223     Document Type: Article

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