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Volumn 25, Issue 1, 2010, Pages 11-16

Establishment and characterization of gastric carcinoma cell clones expressing LMP2A of Epstein-Barr virus

Author keywords

Epstein Barr virus; Gastric carcinoma; Latent membrane protein 2A; Retroviral vector; Tumorigenesis

Indexed keywords

LATENT MEMBRANE PROTEIN 2; LATENT MEMBRANE PROTEIN 2A; RETROVIRUS VECTOR; UNCLASSIFIED DRUG;

EID: 70549097997     PISSN: 11073756     EISSN: 1791244X     Source Type: Journal    
DOI: 10.3892/ijmm_00000307     Document Type: Article
Times cited : (8)

References (38)
  • 1
    • 0037196584 scopus 로고    scopus 로고
    • Epstein-Barr virus
    • Rickinson A: Epstein-Barr virus. Virus Res 82: 109-113, 2002.
    • (2002) Virus Res , vol.82 , pp. 109-113
    • Rickinson, A.1
  • 3
    • 0042467687 scopus 로고    scopus 로고
    • Epstein-Barr virus and oncogenesis: From latent genes to tumours
    • Young LS and Murray PG: Epstein-Barr virus and oncogenesis: from latent genes to tumours. Oncogene 22: 5108-5121, 2003.
    • (2003) Oncogene , vol.22 , pp. 5108-5121
    • Young, L.S.1    Murray, P.G.2
  • 4
    • 50149086269 scopus 로고    scopus 로고
    • Epstein-Barr virus and gastric carcinoma - viral carcinogenesis through epigenetic mechanisms
    • Uozaki H and Fukayama M: Epstein-Barr virus and gastric carcinoma - viral carcinogenesis through epigenetic mechanisms. Int J Clin Exp Pathol 1: 198-216, 2008.
    • (2008) Int J Clin Exp Pathol , vol.1 , pp. 198-216
    • Uozaki, H.1    Fukayama, M.2
  • 5
    • 0028577894 scopus 로고
    • Gastric carcinoma: Monoclonal epithelial malignant cells expressing Epstein-Barr virus latent infection protein
    • Imai S, Koizumi S, Sugiura M, et al: Gastric carcinoma: monoclonal epithelial malignant cells expressing Epstein-Barr virus latent infection protein. Proc Natl Acad Sci USA 91: 9131-9135, 1994.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 9131-9135
    • Imai, S.1    Koizumi, S.2    Sugiura, M.3
  • 6
    • 0028146198 scopus 로고
    • Epstein-Barr virus-associated gastric carcinoma and Epstein-Barr virus infection of the stomach
    • Fukayama M, Hayashi Y, Iwasaki Y, et al: Epstein-Barr virus-associated gastric carcinoma and Epstein-Barr virus infection of the stomach. Lab Invest 71: 73-81, 1994.
    • (1994) Lab Invest , vol.71 , pp. 73-81
    • Fukayama, M.1    Hayashi, Y.2    Iwasaki, Y.3
  • 7
    • 0034838353 scopus 로고    scopus 로고
    • Distinct chromosomal aberrations in Epstein-Barr virus-carrying gastric carcinomas tested by comparative genomic hybridization
    • zur Hausen A, van Grieken NC, Meijer GA, et al: Distinct chromosomal aberrations in Epstein-Barr virus-carrying gastric carcinomas tested by comparative genomic hybridization. Gastroenterology 121: 612-618, 2001.
    • (2001) Gastroenterology , vol.121 , pp. 612-618
    • zur Hausen, A.1    van Grieken, N.C.2    Meijer, G.A.3
  • 8
    • 0032949142 scopus 로고    scopus 로고
    • Epstein-Barr virus promotes epithelial cell growth in the absence of EBNA2 and LMP1 expression
    • Nishikawa J, Imai S, Oda T, Kojima T, Okita K and Takada K: Epstein-Barr virus promotes epithelial cell growth in the absence of EBNA2 and LMP1 expression. J Virol 73: 1286-1292, 1999.
    • (1999) J Virol , vol.73 , pp. 1286-1292
    • Nishikawa, J.1    Imai, S.2    Oda, T.3    Kojima, T.4    Okita, K.5    Takada, K.6
  • 9
    • 0034657266 scopus 로고    scopus 로고
    • Unique transcription pattern of Epstein-Barr virus (EBV) in EBV-carrying gastric adenocarcinomas: Expression of the transforming BARF1 gene
    • zur Hausen A, Brink AA, Craanen ME, Middeldorp JM, Meijer CJ and van den Brule AJ: Unique transcription pattern of Epstein-Barr virus (EBV) in EBV-carrying gastric adenocarcinomas: expression of the transforming BARF1 gene. Cancer Res 60: 2745-2748, 2000.
    • (2000) Cancer Res , vol.60 , pp. 2745-2748
    • zur Hausen, A.1    Brink, A.A.2    Craanen, M.E.3    Middeldorp, J.M.4    Meijer, C.J.5    van den Brule, A.J.6
  • 10
    • 0029781040 scopus 로고    scopus 로고
    • Transcriptional analysis of Epstein-Barr virus gene expression in EBV-positive gastric carcinoma: Unique viral latency in the tumour cells
    • Sugiura M, Imai S, Tokunaga M, et al: Transcriptional analysis of Epstein-Barr virus gene expression in EBV-positive gastric carcinoma: unique viral latency in the tumour cells. Br J Cancer 74: 625-631, 1996.
    • (1996) Br J Cancer , vol.74 , pp. 625-631
    • Sugiura, M.1    Imai, S.2    Tokunaga, M.3
  • 11
    • 0028141364 scopus 로고
    • Epstein-Barr virus protein LMP2A regulates reactivation from latency by negatively regulating tyrosine kinases involved in sIg-mediated signal transduction
    • Miller CL, Lee JH, Kieff E, Burkhardt AL, Bolen JB and Longnecker R: Epstein-Barr virus protein LMP2A regulates reactivation from latency by negatively regulating tyrosine kinases involved in sIg-mediated signal transduction. Infect Agents Dis 3: 128-136, 1994.
    • (1994) Infect Agents Dis , vol.3 , pp. 128-136
    • Miller, C.L.1    Lee, J.H.2    Kieff, E.3    Burkhardt, A.L.4    Bolen, J.B.5    Longnecker, R.6
  • 12
    • 9644279753 scopus 로고    scopus 로고
    • Epstein-Barr virus (EBV) LMP2A mediates B-lymphocyte survival through constitutive activation of the Ras/PI3K/ Akt pathway
    • Portis T and Longnecker R: Epstein-Barr virus (EBV) LMP2A mediates B-lymphocyte survival through constitutive activation of the Ras/PI3K/ Akt pathway. Oncogene 23: 8619-8628, 2004.
    • (2004) Oncogene , vol.23 , pp. 8619-8628
    • Portis, T.1    Longnecker, R.2
  • 13
    • 48849094262 scopus 로고    scopus 로고
    • EBV LMP2A provides a surrogate pre-B cell receptor signal through constitutive activation of the ERK/MAPK pathway
    • Anderson LJ and Longnecker R: EBV LMP2A provides a surrogate pre-B cell receptor signal through constitutive activation of the ERK/MAPK pathway. J Gen Virol 89: 1563-1568, 2008.
    • (2008) J Gen Virol , vol.89 , pp. 1563-1568
    • Anderson, L.J.1    Longnecker, R.2
  • 14
    • 0033761806 scopus 로고    scopus 로고
    • Latent membrane protein 2A-mediated effects on the phosphatidylinositol 3-kinase/Akt pathway
    • Swart R, Ruf IK, Sample J and Longnecker R: Latent membrane protein 2A-mediated effects on the phosphatidylinositol 3-kinase/Akt pathway. J Virol 74: 10838-10845, 2000.
    • (2000) J Virol , vol.74 , pp. 10838-10845
    • Swart, R.1    Ruf, I.K.2    Sample, J.3    Longnecker, R.4
  • 15
    • 0842326032 scopus 로고    scopus 로고
    • Latent membrane protein 2A inhibits transforming growth factor-beta 1-induced apoptosis through the phosphatidylinositol 3-kinase/Akt pathway
    • Fukuda M and Longnecker R: Latent membrane protein 2A inhibits transforming growth factor-beta 1-induced apoptosis through the phosphatidylinositol 3-kinase/Akt pathway. J Virol 78: 1697-1705, 2004.
    • (2004) J Virol , vol.78 , pp. 1697-1705
    • Fukuda, M.1    Longnecker, R.2
  • 16
    • 0027443151 scopus 로고
    • Mutants of Epstein-Barr virus with a selective marker disrupting the TP gene transform B cells and replicate normally in culture
    • Kim OJ and Yates JL: Mutants of Epstein-Barr virus with a selective marker disrupting the TP gene transform B cells and replicate normally in culture. J Virol 67: 7634-7640, 1993.
    • (1993) J Virol , vol.67 , pp. 7634-7640
    • Kim, O.J.1    Yates, J.L.2
  • 17
    • 0026739517 scopus 로고
    • The only domain which distinguishes Epstein-Barr virus latent membrane protein 2A (LMP2A) from LMP2B is dispensable for lymphocyte infection and growth transformation in vitro; LMP2A is therefore nonessential
    • Longnecker R, Miller CL, Miao XQ, Marchini A and Kieff E: The only domain which distinguishes Epstein-Barr virus latent membrane protein 2A (LMP2A) from LMP2B is dispensable for lymphocyte infection and growth transformation in vitro; LMP2A is therefore nonessential. J Virol 66: 6461-6469, 1992.
    • (1992) J Virol , vol.66 , pp. 6461-6469
    • Longnecker, R.1    Miller, C.L.2    Miao, X.Q.3    Marchini, A.4    Kieff, E.5
  • 18
    • 34948821852 scopus 로고    scopus 로고
    • Epstein-Barr virus latent membrane protein 2A is a B-cell receptor mimic and essential for B-cell survival
    • Mancao C and Hammerschmidt W: Epstein-Barr virus latent membrane protein 2A is a B-cell receptor mimic and essential for B-cell survival. Blood 110: 3715-3721, 2007.
    • (2007) Blood , vol.110 , pp. 3715-3721
    • Mancao, C.1    Hammerschmidt, W.2
  • 19
    • 0033756107 scopus 로고    scopus 로고
    • Epstein-Barr virus LMP2A transforms epithelial cells, inhibits cell differentiation, and activates Akt
    • Scholle F, Bendt KM and Raab-Traub N: Epstein-Barr virus LMP2A transforms epithelial cells, inhibits cell differentiation, and activates Akt. J Virol 74: 10681-10689, 2000.
    • (2000) J Virol , vol.74 , pp. 10681-10689
    • Scholle, F.1    Bendt, K.M.2    Raab-Traub, N.3
  • 20
    • 0036721207 scopus 로고    scopus 로고
    • Epstein-Barr virus latent membrane protein 2A regulates c-Jun protein through extracellular signal-regulated kinase
    • Chen SY, Lu J, Shih YC and Tsai CH: Epstein-Barr virus latent membrane protein 2A regulates c-Jun protein through extracellular signal-regulated kinase. J Virol 76: 9556-9561, 2002.
    • (2002) J Virol , vol.76 , pp. 9556-9561
    • Chen, S.Y.1    Lu, J.2    Shih, Y.C.3    Tsai, C.H.4
  • 21
    • 29744450125 scopus 로고    scopus 로고
    • Epstein-Barr-virus-encoded LMP2A induces primary epithelial cell migration and invasion: Possible role in nasopharyngeal carcinoma metastasis
    • Pegtel DM, Subramanian A, Sheen TS, Tsai CH, Golub TR and Thorley-Lawson DA: Epstein-Barr-virus-encoded LMP2A induces primary epithelial cell migration and invasion: possible role in nasopharyngeal carcinoma metastasis. J Virol 79: 15430-15442, 2005.
    • (2005) J Virol , vol.79 , pp. 15430-15442
    • Pegtel, D.M.1    Subramanian, A.2    Sheen, T.S.3    Tsai, C.H.4    Golub, T.R.5    Thorley-Lawson, D.A.6
  • 22
    • 34548156449 scopus 로고    scopus 로고
    • Epstein-Barr virus latent membrane protein 2A mediates transformation through constitutive activation of the Ras/PI3-K/ Akt pathway
    • Fukuda M and Longnecker R: Epstein-Barr virus latent membrane protein 2A mediates transformation through constitutive activation of the Ras/PI3-K/ Akt pathway. J Virol 81: 9299-9306, 2007.
    • (2007) J Virol , vol.81 , pp. 9299-9306
    • Fukuda, M.1    Longnecker, R.2
  • 23
    • 0033825005 scopus 로고    scopus 로고
    • Epstein-Barr virus latent membrane protein 2A has no growth-altering effects when expressed in differentiating epithelia
    • Longan L and Longnecker R: Epstein-Barr virus latent membrane protein 2A has no growth-altering effects when expressed in differentiating epithelia. J Gen Virol 81: 2245-2252, 2000.
    • (2000) J Gen Virol , vol.81 , pp. 2245-2252
    • Longan, L.1    Longnecker, R.2
  • 24
    • 1542315566 scopus 로고    scopus 로고
    • A naturally derived gastric cancer cell line shows latency I Epstein-Barr virus infection closely resembling EBV-associated gastric cancer
    • Oh ST, Seo JS, Moon UY, et al: A naturally derived gastric cancer cell line shows latency I Epstein-Barr virus infection closely resembling EBV-associated gastric cancer. Virology 320: 330-336, 2004.
    • (2004) Virology , vol.320 , pp. 330-336
    • Oh, S.T.1    Seo, J.S.2    Moon, U.Y.3
  • 25
    • 0031038107 scopus 로고    scopus 로고
    • Establishment and characterization of human gastric carcinoma cell lines
    • Park JG, Yang HK, Kim WH, et al: Establishment and characterization of human gastric carcinoma cell lines. Int J Cancer 70: 443-449, 1997.
    • (1997) Int J Cancer , vol.70 , pp. 443-449
    • Park, J.G.1    Yang, H.K.2    Kim, W.H.3
  • 26
    • 0020625970 scopus 로고
    • Establishment and characterization of an in vitro model system for human adenocarcinoma of the stomach
    • Barranco SC, Townsend CM Jr, Casartelli C, et al: Establishment and characterization of an in vitro model system for human adenocarcinoma of the stomach. Cancer Res 43: 1703-1709, 1983.
    • (1983) Cancer Res , vol.43 , pp. 1703-1709
    • Barranco, S.C.1    Townsend Jr, C.M.2    Casartelli, C.3
  • 27
    • 0030921087 scopus 로고    scopus 로고
    • Epstein-Barr virus infection of human gastric carcinoma cells: Implication of the existence of a new virus receptor different from CD21
    • Yoshiyama H, Imai S, Shimizu N and Takada K: Epstein-Barr virus infection of human gastric carcinoma cells: implication of the existence of a new virus receptor different from CD21. J Virol 71: 5688-5691, 1997.
    • (1997) J Virol , vol.71 , pp. 5688-5691
    • Yoshiyama, H.1    Imai, S.2    Shimizu, N.3    Takada, K.4
  • 28
    • 0037130481 scopus 로고    scopus 로고
    • Overexpression of a dominant negative form of STAT3 selectively impairs hematopoietic stem cell activity
    • Oh IH and Eaves CJ: Overexpression of a dominant negative form of STAT3 selectively impairs hematopoietic stem cell activity. Oncogene 21: 4778-4787, 2002.
    • (2002) Oncogene , vol.21 , pp. 4778-4787
    • Oh, I.H.1    Eaves, C.J.2
  • 29
    • 0018247640 scopus 로고
    • Biochemical transfer of single-copy eucaryotic genes using total cellular DNA as donor
    • Wigler M, Pellicer A, Silverstein S and Axel R: Biochemical transfer of single-copy eucaryotic genes using total cellular DNA as donor. Cell 14: 725-731, 1978.
    • (1978) Cell , vol.14 , pp. 725-731
    • Wigler, M.1    Pellicer, A.2    Silverstein, S.3    Axel, R.4
  • 30
    • 0033604292 scopus 로고    scopus 로고
    • Tyrosines 60, 64, and 101 of Epstein-Barr virus LMP2A are not essential for blocking B cell signal transduction
    • Swart R, Fruehling S and Longnecker R: Tyrosines 60, 64, and 101 of Epstein-Barr virus LMP2A are not essential for blocking B cell signal transduction. Virology 263: 485-495, 1999.
    • (1999) Virology , vol.263 , pp. 485-495
    • Swart, R.1    Fruehling, S.2    Longnecker, R.3
  • 31
    • 0031661310 scopus 로고    scopus 로고
    • Tyrosine 112 of latent membrane protein 2A is essential for protein tyrosine kinase loading and regulation of Epstein-Barr virus latency
    • Fruehling S, Swart R, Dolwick KM, Kremmer E and Longnecker R: Tyrosine 112 of latent membrane protein 2A is essential for protein tyrosine kinase loading and regulation of Epstein-Barr virus latency. J Virol 72: 7796-7806, 1998.
    • (1998) J Virol , vol.72 , pp. 7796-7806
    • Fruehling, S.1    Swart, R.2    Dolwick, K.M.3    Kremmer, E.4    Longnecker, R.5
  • 32
    • 0030754766 scopus 로고    scopus 로고
    • The immunoreceptor tyrosine-based activation motif of Epstein-Barr virus LMP2A is essential for blocking BCR-mediated signal transduction
    • Fruehling S and Longnecker R: The immunoreceptor tyrosine-based activation motif of Epstein-Barr virus LMP2A is essential for blocking BCR-mediated signal transduction. Virology 235: 241-251, 1997.
    • (1997) Virology , vol.235 , pp. 241-251
    • Fruehling, S.1    Longnecker, R.2
  • 33
    • 0032836599 scopus 로고    scopus 로고
    • Sequence variations of Epstein-Barr virus LMP2A gene in gastric carcinoma in Japan
    • Tanaka M, Kawaguchi Y, Yokofujita J, Takagi M, Eishi Y and Hirai K: Sequence variations of Epstein-Barr virus LMP2A gene in gastric carcinoma in Japan. Virus Genes 19: 103-111, 1999.
    • (1999) Virus Genes , vol.19 , pp. 103-111
    • Tanaka, M.1    Kawaguchi, Y.2    Yokofujita, J.3    Takagi, M.4    Eishi, Y.5    Hirai, K.6
  • 34
    • 0014943020 scopus 로고
    • EBV DNA in biopsies of Burkitt tumours and anaplastic carcinomas of the nasopharynx
    • zur Hausen H, Schulte-Holthausen H, Klein G, et al: EBV DNA in biopsies of Burkitt tumours and anaplastic carcinomas of the nasopharynx. Nature 228: 1056-1058, 1970.
    • (1970) Nature , vol.228 , pp. 1056-1058
    • zur Hausen, H.1    Schulte-Holthausen, H.2    Klein, G.3
  • 36
    • 0036235391 scopus 로고    scopus 로고
    • Retroviral vectors for human gene delivery
    • McTaggart S and Al-Rubeai M: Retroviral vectors for human gene delivery. Biotechnol Adv 20: 1-31, 2002.
    • (2002) Biotechnol Adv , vol.20 , pp. 1-31
    • McTaggart, S.1    Al-Rubeai, M.2
  • 37
    • 33846066318 scopus 로고    scopus 로고
    • Expression of viral microRNAs in Epstein-Barr virus-associated gastric carcinoma
    • Kim do N, Chae HS, Oh ST, et al: Expression of viral microRNAs in Epstein-Barr virus-associated gastric carcinoma. J Virol 81: 1033-1036, 2007.
    • (2007) J Virol , vol.81 , pp. 1033-1036
    • Kim do, N.1    Chae, H.S.2    Oh, S.T.3
  • 38
    • 2342420041 scopus 로고    scopus 로고
    • Identification of virus-encoded microRNAs
    • Pfeffer S, Zavolan M, Grasser FA, et al: Identification of virus-encoded microRNAs. Science 304: 734-736, 2004.
    • (2004) Science , vol.304 , pp. 734-736
    • Pfeffer, S.1    Zavolan, M.2    Grasser, F.A.3


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