The role of serum chromogranin A in diarrhoea predominant irritable bowel syndrome

Journal of Gastrointestinal and Liver Diseases

Volumn 18, Issue 1, 2009, Pages 23-26

  Sidhu, Reena ^a   McAlindon, Mark E ^a   Leeds, John S ^a   Skilling, Jessica ^a   Sanders, David S ^a  

^a ROYAL HALLAMSHIRE HOSPITAL   (United Kingdom)

Author keywords

Diarrhoea predominant; Irritable bowel syndrome; Serum chromogranin A

Indexed keywords

CHROMOGRANIN A; OCTREOTIDE;

ADULT; AGED; ARTICLE; CARCINOID; CLINICAL TRIAL; DIARRHEA; DISEASE MARKER; DRUG RESPONSE; FEMALE; HUMAN; IRRITABLE COLON; LEIOMYOMA; MAJOR CLINICAL STUDY; MALE; PROSPECTIVE STUDY; PROTEIN BLOOD LEVEL; RECTUM TUMOR; STOMACH ADENOCARCINOMA; STOMACH LEIOMYOMA; SYMPTOM;

BIOLOGICAL MARKERS; CHROMOGRANIN A; DIARRHEA; FEMALE; GASTROINTESTINAL AGENTS; HUMANS; IRRITABLE BOWEL SYNDROME; MALE; MIDDLE AGED; OCTREOTIDE; PATIENT SELECTION; PREDICTIVE VALUE OF TESTS; PROSPECTIVE STUDIES; SEVERITY OF ILLNESS INDEX; TIME FACTORS; TREATMENT OUTCOME; UP-REGULATION;

EID: 70549084957     PISSN: 18418724     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (18)

1. Saito YA, Schoenfeld P, Locke GR 3rd. The epidemiology of irritable bowel syndrome in North America: a systematic review. Am J Gastroenterol 2002; 97: 1910-1915. (Pubitemid 34906835)
2. Drossman DA, Camilleri M, Mayer EA, Whitehead WE. AGA technical review on irritable bowel syndrome. Gastroenterology 2002; 123: 2108-2131. (Pubitemid 35408332)
3. Spiller R, Aziz Q, Creed F, et al. Guidelines on the irritable bowel syndrome: mechanisms and practical management. Gut 2007; 56: 1770-1798. (Pubitemid 350206308)
4. Manning AP, Thompson WG, Heaton KW, Morris AF. Towards positive diagnosis of the irritable bowel. Br Med J 1978; 2: 653-654.
5. Hahn BA, Yan S, Strassels S. Impact of irritable bowel syndrome on quality of life and resource use in the United States and United Kingdom. Digestion 1999; 60: 77-81. (Pubitemid 29042096)
6. Taupenot L, Harper KL, O'Connor DT. The chromograninsecretogranin family. N Engl J Med 2003; 348: 1134-1149.
7. Wiedenmann B, Huttner WB. Synaptophysin and chromogranins/ secretogranins-widespread constituents of distinct types of neuroendocrine vesicles and new tools in tumor diagnosis. Virchows Arch B Cell Pathol Incl Mol Pathol 1989; 58: 95-121. (Pubitemid 20012954)
8. Sondenaa K, Sen J, Heinle F, Fjetland L, Gudlaugsson E, Syversen U. Chromogranin A, a marker of the therapeutic success of resection of neuroendocrine liver metastases: preliminary report. World J Surg 2004; 28: 890-895. (Pubitemid 39391893)
9. Helle KB, Corti A, Metz-Boutigue MH, Tota B. The endocrine role for chromogranin A: a prohormone for peptides with regulatory properties. Cell Mol Life Sci 2007; 64: 2863-2886. (Pubitemid 351152248)
10. Simonsson M, Eriksson S, Hakanson R, et al. Endocrine cells in the human oxyntic mucosa. A histochemical study. Scand J Gastroenterol 1988; 23: 1089-1099. (Pubitemid 18279234)
11. Dunlop SP, Jenkins D, Neal KR, Spiller RC. Relative importance of enterochromaffin cell hyperplasia, anxiety, and depression in postinfectious IBS. Gastroenterology 2003; 125: 1651-1659. (Pubitemid 37500429)
12. Gershon MD. Review article: roles played by 5-hydroxytryptamine in the physiology of the bowel. Aliment Pharmacol Ther 1999; 13 Suppl 2: 15-30.
13. Szilagyi A, Shrier I. Systematic review: the use of somatostatin or octreotide in refractory diarrhoea. Aliment Pharmacol Ther 2001; 15: 1889-1897. (Pubitemid 34014344)
14. O'Connor DT, Pandlan MR, Carlton E, Cervenka JH, Hslao RJ. Rapid radioimmunoassay of circulating chromogranin A: in vitro stability, exploration of the neuroendocrine character of neoplasia, and assessment of the effects of organ failure. Clin Chem 1989; 35: 1631-1637.
15. O'Connor DT, Bernstein KN. Radioimmunoassay of chromogranin A in plasma as a measure of exocytotic sympathoadrenal activity in normal subjects and patients with pheochromocytoma. N Engl J Med 1984; 311: 764-770.
16. Militello C, Cannizzaro R, Pradella P, et al. Usefulness of chromogranin A determination in the diagnosis of neuroendocrine neoplasia. Chir Ital 1999; 51: 45-51.
17. Skipper M, Lewis J. Getting to the guts of enteroendocrine differentiation. Nat Genet 2000; 24: 3-4.
18. Syversen U, Halvorsen T, Marvik R, Waldum HL. Neuroendocrine differentiation in colorectal carcinomas. Eur J Gastroenterol Hepatol 1995; 7: 667-674.