Crystal structure and catalytic mechanism of 4-methylmuconolactone methylisomerase

Journal of Biological Chemistry

Volumn 284, Issue 47, 2009, Pages 32709-32716

  Marín, Macarena ^a   Heinz, Dirk W ^a   Pieper, Dietmar H ^a   Klink, Björn U ^a  

^a HELMHOLTZ CENTRE FOR INFECTION RESEARCH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

4-METHYLCATECHOL; ACTIVE SITE; BACTERIAL SPECIES; BUFFER MOLECULES; CATALYTIC ACTIVITY; CATALYTIC MECHANISMS; CATALYTIC RESIDUE; HOMODIMERIC COMPLEXES; MARGINAL EFFECTS; SITE DIRECTED MUTAGENESIS; STRUCTURAL GENOMICS; SUBSTITUTED AROMATIC; SUBSTRATE AFFINITY; WILD TYPES;

ELECTRON TRANSITIONS; FLUORINE CONTAINING POLYMERS; GENE ENCODING; ISOMERIZATION; ISOMERS; QUANTUM CHEMISTRY; STRUCTURAL ANALYSIS;

CRYSTAL STRUCTURE;

4 METHYLMUCONOLACTONE METHYLISOMERASE; BACTERIAL ENZYME; FERREDOXIN; HISTIDINE; TYROSINE; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CONTROLLED STUDY; CRYSTAL STRUCTURE; CUPRIAVIDUS NECATOR; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME DEGRADATION; ENZYME KINETICS; ENZYME STRUCTURE; HYDROGEN BOND; ISOMERIZATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS;

BACTERIAL PROTEINS; CATALYSIS; CATALYTIC DOMAIN; CLONING, MOLECULAR; CRYSTALLOGRAPHY, X-RAY; CYSTEINE; FERREDOXINS; GENOMICS; HISTIDINE; INTRAMOLECULAR TRANSFERASES; ISOMERASES; KINETICS; LACTONES; MODELS, CHEMICAL; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PSEUDOMONAS; SUBSTRATE SPECIFICITY;

BACTERIA (MICROORGANISMS); CUPRIAVIDUS NECATOR; PSEUDOMONAS;

EID: 70450277226     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.024604     Document Type: Article

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