Higher skeletal muscular metabolic reserve capacity in COPD patients than healthy subjects

Scandinavian Journal of Medicine and Science in Sports

Volumn 19, Issue 6, 2009, Pages 857-864

  Rud, B ^a   Christensen, C C ^b   Ryg, M ^b   Edvardsen, A ^b   Skumlien, S ^b   Hallen J ^a  

^a NORWEGIAN SCHOOL OF SPORT SCIENCES   (Norway)

^b Glittreklinikken ^*  (Norway)

Author keywords

Central limitations; Lung disease; Muscular efficiency; Muscular metabolic capacity

Indexed keywords

LACTIC ACID;

ADULT; AGED; ARTICLE; BLOOD; BLOOD PRESSURE; CHRONIC OBSTRUCTIVE LUNG DISEASE; EXERCISE; EXERCISE TOLERANCE; FEMALE; HEART RATE; HUMAN; LUNG GAS EXCHANGE; MALE; METABOLISM; MIDDLE AGED; NORWAY; OXYGEN CONSUMPTION; PATHOPHYSIOLOGY; PHYSIOLOGY; SKELETAL MUSCLE;

ADULT; AGED; BLOOD PRESSURE; EXERCISE; EXERCISE TOLERANCE; FEMALE; HEART RATE; HUMANS; LACTIC ACID; MALE; MIDDLE AGED; MUSCLE, SKELETAL; NORWAY; OXYGEN CONSUMPTION; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; PULMONARY GAS EXCHANGE;

EID: 70450230375     PISSN: 09057188     EISSN: 16000838     Source Type: Journal    
DOI: 10.1111/j.1600-0838.2008.00846.x     Document Type: Article

References (24)

1. Aaron EA, Seow KC, Johnson BD, Dempsey JA. Oxygen cost of exercise hyperpnea: implications for performance. J Appl Physiol 1992 : 72 : 1818 1825.
2. Allaire J, Maltais F, Doyon JF, Noel M, Leblanc P, Carrier G, Simard C, Jobin J. Peripheral muscle endurance and the oxidative profile of the quadriceps in patients with COPD. Thorax 2004 : 59 : 673 678.
3. Andersen P, Saltin B. Maximal perfusion of skeletal muscle in man. J Physiol 1985 : 366 : 233 249.
4. Baarends EM, Schols AM, Akkermans MA, Wouters EF. Decreased mechanical efficiency in clinically stable patients with COPD. Thorax 1997 : 52 : 981 986.
5. Gallagher D, Visser M, deMeersman RE, Sepulveda D, Baumgartner RN, Pierson RN, Harris T, Heymsfield SB. Appendicular skeletal muscle mass: effects of age, gender, and ethnicity. J Appl Physiol 1997 : 83 : 229 239.
6. GOLD. From the Global Strategy for the Diagnosis, Management and Prevention of COPD, Global Initiative for Chronic Obstructive Lung Disease (GOLD). Lung Disease. 2006. Available from :. Ref Type: Internet Communication
7. Hallén J, Saltin B, Sejersted OM. K+ balance during exercise and role of beta-adrenergic stimulation. Am J Physiol 1996 : 270 : R1347 R1354.
8. Jakobsson P, Jorfeldt L, Henriksson J. Metabolic enzyme activity in the quadriceps femoris muscle in patients with severe chronic obstructive pulmonary disease. Am J Respir Crit Care Med 1995 : 151 : 374 377.
9. Jobin J, Maltais F, Doyon JF, Leblanc P, Simard PM, Simard AA, Simard C. Chronic obstructive pulmonary disease: capillarity and fiber-type characteristics of skeletal muscle. J Cardiopulm Rehabil 1998 : 18 : 432 437. (Pubitemid 29024891)
10. Jones PR, Pearson J. Anthropometric determination of leg fat and muscle plus bone volumes in young male and female adults. J Physiol 1969 : 204 : 63P 66P.
11. Levison H, Cherniack RM. Ventilatory cost of exercise in chronic obstructive pulmonary disease 2. J Appl Physiol 1968 : 25 : 21 27.
12. Maltais F, Jobin J, Sullivan MJ, Bernard S, Whittom F, Killian KJ, Desmeules M, Belanger M, Leblanc P. Metabolic and hemodynamic responses of lower limb during exercise in patients with COPD. J Appl Physiol 1998 : 84 : 1573 1580.
13. Maltais F, Leblanc P, Whittom F, Simard C, Marquis K, Belanger M, Breton MJ, Jobin J. Oxidative enzyme activities of the vastus lateralis muscle and the functional status in patients with COPD. Thorax 2000 : 55 : 848 853.
14. Mortensen SP, Dawson EA, Yoshiga CC, Dalsgaard MK, Damsgaard R, Secher NH, Gonzalez-Alonso J. Limitations to systemic and locomotor limb muscle oxygen delivery and uptake during maximal exercise in humans. J Physiol 2005 : 566 : 273 285.
15. Radegran G, Blomstrand E, Saltin B. Peak muscle perfusion and oxygen uptake in humans: importance of precise estimates of muscle mass. J Appl Physiol 1999 : 87 : 2375 2380.
16. Richardson RS. Skeletal muscle dysfunction vs muscle disuse in patients with COPD. J Appl Physiol 1999 : 86 : 1751 1753.
17. Richardson RS, Frank LR, Haseler LJ. Dynamic knee-extensor and cycle exercise: functional MRI of muscular activity. Int J Sports Med 1998 : 19 : 182 187.
18. 2 max in the exercise-trained human quadriceps. J Appl Physiol 1999a : 86 : 1048 1053.
19. 2 with small muscle mass exercise. Am J Respir Crit Care Med 2004 : 169 : 89 96.
20. Richardson RS, Sheldon J, Poole DC, Hopkins SR, Ries AL, Wagner PD. Evidence of skeletal muscle metabolic reserve during whole body exercise in patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 1999b : 159 : 881 885.
21. Rowell LB, Saltin B, Kiens B, Christensen NJ. Is peak quadriceps blood flow in humans even higher during exercise with hypoxemia? Am J Physiol 1986 : 251 : H1038 H1044.
22. Sala E, Roca J, Marrades RM, Alonso J, Gonzalez De Suso JM, Moreno A, Barbera JA, Nadal J, de Jover L, Rodriguez-Roisin R, Wagner PD. Effects of endurance training on skeletal muscle bioenergetics in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 1999 : 159 : 1726 1734.
23. Weber CL, Schneider DA. Maximal accumulated oxygen deficit expressed relative to the active muscle mass for cycling in untrained male and female subjects. Eur J Appl Physiol 2000 : 82 : 255 261.
24. Whittom F, Jobin J, Simard PM, Leblanc P, Simard C, Bernard S, Belleau R, Maltais F. Histochemical and morphological characteristics of the vastus lateralis muscle in patients with chronic obstructive pulmonary disease. Med Sci Sports Exerc 1998 : 30 : 1467 1474. (Pubitemid 28465510)