Successful treatment of chronic resistant alcoholism by deep brain stimulation of nucleus accumbens: First experience with three cases

Pharmacopsychiatry

Volumn 42, Issue 6, 2009, Pages 288-291

  Muller U J ^a   Sturm, V ^b   Voges, J ^a   Heinze, H J ^a   Galazky, I ^a   Heldmann, M ^a   Scheich, H ^c   Bogerts, B ^a,d  

^a OTTO VON GUERICKE UNIVERSITY   (Germany)

^b UNIVERSITY OF COLOGNE   (Germany)

^c LEIBNIZ INSTITUTE FOR NEUROBIOLOGY   (Germany)

^d UNIVERSITY HOSPITAL MAGDEBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ALCOHOL ABSTINENCE; ALCOHOLISM; ARTICLE; BRAIN DEPTH STIMULATION; CASE REPORT; CHRONIC DISEASE; FOLLOW UP; HUMAN; MALE; NEUROMODULATION; NUCLEUS ACCUMBENS; PRIORITY JOURNAL; TREATMENT OUTCOME; TREATMENT RESPONSE;

ADULT; ALCOHOLISM; CHRONIC DISEASE; DEEP BRAIN STIMULATION; FOLLOW-UP STUDIES; HUMANS; MALE; NUCLEUS ACCUMBENS; QUESTIONNAIRES; SEVERITY OF ILLNESS INDEX; TIME FACTORS; TREATMENT OUTCOME;

EID: 70450225412     PISSN: 01763679     EISSN: 14390795     Source Type: Journal    
DOI: 10.1055/s-0029-1233489     Document Type: Article

References (15)

1. Everitt BJ, Robbins TW. Neural systems of reinforcement for drug addiction: from actions to habits to compulsion. Nat Neurosci 2005; 8: 1481-1489
2. Greenberg BD, Malone DA, Friehs GM et al. Three-year outcomes in deep brain stimulation for highly resistant obsessive-compulsive disorder. Neuropsychopharmacology 2006; 31: 2384-2393
3. Heinz A, Beck A, Gruesser SM. Identifying the neural circuitry of alcohol craving and relapse vulnerability. Addiction Biology 2008; 14: 108-118
4. Küfner H, Feuerlein W. Inpatient treatment for alcoholism, a multicentre evaluation study. Berlin: Springer; 1989
5. Kuhn J, Lenartz D, Huff W et al. Remission of alcohol dependency following deep brain stimulation of the nucleus accumbens: valuable therapeutic implications? J Neurol Neurosurg Psychiatry 2007; 78: 1152-1153
6. Liu H-Y, Jin J, Tang J-S et al. Chronic deep brain stimulation in the rat nucleus accumbens and its effect on morphine reinforcement. Addiction Biology 2008; 13: 40-46 (Pubitemid 351202140)
7. Mai JK, Assheuer J, Paxinos G. Atlas of the Human Brain. San Diego: Academic Press; 1997
8. Mann K, Schaefer DR, Laengle G et al. The long-term course of alcoholism, 5, 10 and 16 years after treatment. Addiction 2005; 100: 797-805
9. Schlaepfer T, Cohen MX, Frick C et al. Deep brain stimulation to reward circuitry alleviates anhedonia in refractory major depression. Neuropsychopharmacology 2008; 33: 368-377 (Pubitemid 350243349)
10. Sher L. Alcoholism and suicidal behaviour: a clinical overview. Acta Psychiatr Scand 2006; 113: 13-22 (Pubitemid 43339084)
11. Soyka M, Kranzler HR, Berglund M et al. World Federation of Societies of Biological Psychiatry (WFSBP) Guidelines for Biological Treatment of Substance Use and Related Disorders, Part 1: Alcoholism. World J Biol Psychiatry 2008; 9: 6-23 (Pubitemid 351250516)
12. Sturm V, Lenartz D, Koulousakis A et al. The nucleus accumbens: a target for deep brain stimulation in obsessive-compulsive- and anxiety-disorders. J Chem Neuroanat 2003; 26: 293-299 (Pubitemid 38077152)
13. Voges J, Hilker R, Bötzel K et al. Thirty days complication rate following surgery performed for deep-brain-stimulation. Mov Disord 2007; 22: 1486-1489 (Pubitemid 47280638)
14. Voges J, Volkmann J, Allert N et al. Bilateral high-frequency stimulation in the subthalamic nucleus for the treatment of Parkinson disease: correlation of therapeutic eff ect with anatomical electrode position. J Neurosurg 2002; 96: 269-279 (Pubitemid 34230241)
15. WHO. Global Status Report on Alcohol. http://www.who.int/substance-abuse/ publications/global-status-report-2004-overview.pdf 2004