Patient-reported outcomes in a survey of patients treated with oral antihyperglycaemic medications: Associations with hypoglycaemia and weight gain

Diabetes, Obesity and Metabolism

Volumn 11, Issue 12, 2009, Pages 1138-1144

  Marrett, E ^a,b   Stargardt, T ^a,c   Mavros, P ^a   Alexander, C M ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

^b UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY   (United States)

^c INSTITUTE OF EPIDEMIOLOGY   (Germany)

Author keywords

Hypoglycaemia; Oral antihyperglycaemic agents; Patient reported outcomes; Type 2 diabetes; Weight gain

Indexed keywords

2,4 THIAZOLIDINEDIONE DERIVATIVE; ALPHA GLUCOSIDASE INHIBITOR; DIPEPTIDYL PEPTIDASE IV INHIBITOR; EXENDIN 4; MEGLITINIDE; METFORMIN; ORAL ANTIDIABETIC AGENT; SULFONYLUREA;

ADULT; ARTICLE; DISEASE SEVERITY; FEMALE; HEALTH SURVEY; HUMAN; HYPOGLYCEMIA; INTERNET; MAJOR CLINICAL STUDY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; QUALITY OF LIFE; QUESTIONNAIRE; SATISFACTION; SCORING SYSTEM; SELF REPORT; SIDE EFFECT; SYMPTOM; TREATMENT OUTCOME; UNITED STATES; WEIGHT GAIN;

ADMINISTRATION, ORAL; ANXIETY; BODY WEIGHT; DIABETES MELLITUS, TYPE 2; FEMALE; HUMANS; HYPOGLYCEMIA; HYPOGLYCEMIC AGENTS; INTERNET; MALE; MIDDLE AGED; QUALITY OF LIFE; QUESTIONNAIRES; TREATMENT OUTCOME; UNITED STATES; WEIGHT GAIN;

EID: 70450203582     PISSN: 14628902     EISSN: 14631326     Source Type: Journal    
DOI: 10.1111/j.1463-1326.2009.01123.x     Document Type: Article

References (24)

1. Koro CE, Boialin SJ, Bourgeois N. Glycemic control from 1988 to 2000 among U.S. adults diagnosed with type 2 diabetes-a preliminary report. Diabetes Care 2004, 27:17-20.
2. Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes. Lancet 1998, 352:837-853. The UKPDS Research Group
3. Cryer PE, Childs BP. Negotiating the barrier of hypoglycemia in diabetes. Diabetes Spectrum 2002, 15:20-27.
4. Cryer PE. Hypoglycemia: the limiting factor in the glycaemic management of Type 1 and Type 2 Diabetes. Diabetologia 2002, 45:937-948.
5. Lundkvist J, Berne C, Bolinder B. The economic and quality of life impact of hypoglycemia. Eur J Health Econ 2005, 6:197-202.
6. Miller CD, Phillips LS, Ziemer DC. Hypoglycemia in patients with type 2 diabetes mellitus. Arch Intern Med 2001, 161:1653-1659.
7. Alvarez Guisasola F, Tofe Povedano S, Krishnarajah G. Hypoglycaemic symptoms, treatment satisfaction, adherence and their associations with glycaemic goal in patients with type 2 diabetes mellitus: findings from the Real-Life Effectiveness and Care Patterns of Diabetes Management (RECAP-DM) Study. Diabetes Obes Metab 2008, 10(Suppl 1):25-32.
8. Murata GH, Duckworth WC, Hoffman RM. Hypoglycemia in type 2 diabetes: a critical review. Biomed Pharmacother 2004, 58:551-559.
9. Dennett SL, Boye KS, Yurgin NR. The impact of body weight on patient utilities with or without type 2 diabetes: a review of the medical literature. Value Health 2008, 11:478-486.
10. Maggio CA, Pi-Sunyer FX. Obesity and type 2 diabetes. Endocrinol Metab Clin North Am 2003, 32:805-822.
11. Hassan MK, Joshi AV, Madhavan SS. Obesity and health-related quality of life: a cross-sectional analysis of the US population. Int J Obes 2003, 27:1227-1232.
12. Childs BP, Clark NG, Cox DJ. Defining and reporting hypoglycemia in diabetes-a report from the American Diabetes Association Workgroup on Hypoglycemia. Diabetes Care 2005, 28:1245-1249.
13. Atkinson MJ, Sinha A, Hass SL. Validation of a general measure of treatment satisfaction, the Treatment Satisfaction Questionnaire for Medication (TSQM), using a national panel study of chronic disease. Health Qual Life Outcomes 2004, 2:12.
14. Cox DJ, Irvine A, Gonderfrederick L. Fear of hypoglycemia-quantification, validation, and utilization. Diabetes Care 1987, 10:617-621.
15. Brooks R. EuroQol: the current state of play. Health Policy 1996, 37:53-72.
16. Shaw JW, Johnson JA, Coons SJ. US valuation of the EQ-5D health states-development and testing of the D1 valuation model. Medical Care 2005, 43:203-220.
17. Vexiau P, Mavros P, Krishnarajah G. Hypoglycaemia in patients with type 2 diabetes treated with a combination of metformin and sulphonylurea therapy in France. Diabetes Obes Metab 2008, 10:16-24.
18. Wild D, von Maltzahn R, Brohan E. A critical review of the literature on fear of hypoglycemia in diabetes: implications for diabetes management and patient education. Patient Educ Couns 2007, 68:10-15.
19. Brod M, Cobden D, Lammert M. Examining correlates of treatment satisfaction for injectable insulin in type 2 diabetes: lessons learned from a clinical trial comparing biphasic and basal analogues. Health Qual Life Outcomes 2007, 5:8.
20. Ross SA. Controlling diabetes: the need for intensive therapy and barriers in clinical management. Diabetes Res Clin Prac 2004, 65:S29-S34.
21. Rubin RR. Adherence to pharmacologic therapy in patients with type 2 diabetes mellitus. Am J Med 2005, 118:27-34.
22. Grant RW, Devita NG, Singer DE. Polypharmacy and medication adherence in patients with type 2 diabetes. Diabetes Care 2003, 26:1408-1412.
23. Chao J, Nau DP, Aikens JE. Patient-reported perceptions of side effects of antihyperglycemic medication and adherence to medication regimens in persons with diabetes mellitus. Clin Ther 2007, 29:177-180.
24. Atkinson MJ, Kumar R, Cappelleri JC. Hierarchical construct validity of the treatment satisfaction questionnaire for medication (TSQM version II) among outpatient pharmacy consumers. Value Health 2005, 8(Suppl. 1):S9-S24.