Prevalence, phenotypic and genetic characteristics of prolyliminopeptidase- negative Neisseria gonorrhoeae isolates in Sweden during 2000-2007

APMIS

Volumn 117, Issue 12, 2009, Pages 900-904

  Johansson, Emma ^a   Fredlund, Hans ^a   Unemo, Magnus ^a  

^a ÖREBRO UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Neisseria gonorrhoeae; NG MAST; Pip and porB gene sequencing; Prolyliminopeptidase; Sweden

Indexed keywords

AMPICILLIN; AZITHROMYCIN; BACTERIAL ANTIGEN; CEFIXIME; CEFTRIAXONE; CIPROFLOXACIN; PROLINE IMINOPEPTIDASE; SPECTINOMYCIN;

ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL GENE; BACTERIAL STRAIN; BACTERIUM CULTURE; BACTERIUM IDENTIFICATION; BACTERIUM ISOLATE; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; GENE DELETION; GENE SEQUENCE; GENETIC ANALYSIS; HUMAN; MALE; MINIMUM INHIBITORY CONCENTRATION; NEISSERIA GONORRHOEAE; NONHUMAN; PHENOTYPE; PREVALENCE; PRIORITY JOURNAL; SEQUENCE ANALYSIS; SEROTYPE; SINGLE NUCLEOTIDE POLYMORPHISM; SPECIES IDENTIFICATION; SWEDEN;

ALLELES; AMINOPEPTIDASES; BACTERIAL PROTEINS; GENE DELETION; GONORRHEA; HUMANS; MUTAGENESIS, INSERTIONAL; NEISSERIA GONORRHOEAE; PREVALENCE; SWEDEN;

EID: 70450199787     PISSN: 09034641     EISSN: 16000463     Source Type: Journal    
DOI: 10.1111/j.1600-0463.2009.02552.x     Document Type: Article

References (18)

1. Whiley DM, Tapsall JW, Sloots TP. Nucleic acid amplification testing for Neisseria gonorrhoeae: an ongoing challenge. J Mol Diagn 2006 8 : 3 15.
2. Workowski KA, Berman SM, Douglas JM Jr. Emerging antimicrobial resistance in Neisseria gonorrhoeae: urgent need to strengthen prevention strategies. Ann Intern Med 2008 148 : 606 613.
3. Tapsall J. Multidrug-resistant Neisseria gonorrhoeae. CMAJ 2009 180 : 268 269.
4. Unemo M, Fasth O, Fredlund H, Limnios A, Tapsall J. Phenotypic and genetic characterization of the 2008 WHO Neisseria gonorrhoeae reference strain panel intended for global quality assurance and quality control of gonococcal antimicrobial resistance surveillance for public health purposes. J Antimicrob Chemother 2009 63 : 1142 1151.
5. Tapsall JW, Ndowa F, Lewis DA, Unemo M. Meeting the public health challenge of multidrug- and extensively drug-resistant Neisseria gonorrhoeae. Expert Rev Anti Infect Ther 2009 7 : 821 834.
6. Albertson NH, Koomey M. Molecular cloning and characterization of a proline iminopeptidase gene from Neisseria gonorrhoeae. Mol Microbiol 1993 9 : 1203 1211.
7. Blackmore T, Herrera G, Shi S, Bridgewater P, Wheeler L, Byrne J. Characterization of prolyl iminopeptidase-deficient Neisseria gonorrhoeae. J Clin Microbiol 2005 43 : 4189 4190.
8. Palmer HM, Wu S, Gough KR, Hemming MN, Hassan I, Turner A. An increase in prolyliminopeptidase-negative isolation of Neisseria gonorrhoeae in the United Kingdom is associated with the spread of one clonal strain of the organism. Proceedings of the 13th International Pathogenic Neisseria Conference, Oslo, Norway, 2002. (abstr p387)
9. Unemo M, Palmer HM, Blackmore T, Herrera G, Fredlund H, Limnios A, et al. Global transmission of prolyliminopeptidase-negative Neisseria gonorrhoeae strains: implications for changes in diagnostic strategies. Sex Transm Infect 2007 83 : 47 51.
10. Fjeldsøe-Nielsen H, Unemo M, Fredlund H, Hjorth SV, Berthelsen LM, Palmer HM, et al. Phenotypic and genotypic characterization of prolyliminopeptidase-negative Neisseria gonorrhoeae isolates in Denmark. Eur J Clin Microbiol Infect Dis 2005 24 : 280 283.
11. Alexander S, Ison C. Evaluation of commercial kits for the identification of Neisseria gonorrhoeae. J Med Microbiol 2005 54 : 827 831.
12. Limnios EA, Nguyen NL, Ray S, McIver CJ, Tapsall J. Dynamics of appearance and expansion of a prolyliminopeptidase-negative subtype among Neisseria gonorrhoeae isolates collected in Sydney, Australia, from 2002 to 2005. J Clin Microbiol 2006 44 : 1400 1404.
13. Alexander S, Martin IMC, Fenton K, Ison CA. The prevalence of proline iminopeptidase negative Neisseria gonorrhoeae through England and Wales. Sex Transm Infect 2006 82 : 280 282.
14. Otero L, Alvarez-Argüelles M, Villar H, Díaz-Gigante J, Carreño F, Vázquez F, et al. The prevalence of Neisseria gonorrhoeae negative for proline iminopeptidase in Asturias, Spain. Sex Transm Infect 2007 83 : 76.
15. Unemo M, Olcén P, Berglund T, Albert J, Fredlund H. Molecular epidemiology of Neisseria gonorrhoeae: sequence analysis of the porB gene confirms presence of two circulating strains. J Clin Microbiol 2002 40 : 3741 3749.
16. Berglund T, Unemo M, Olcén P, Giesecke J, Fredlund H. One year of Neisseria gonorrhoeae isolates in Sweden: the prevalence study of antibiotic susceptibility shows relation to the geographic area of exposure. Int J STD AIDS 2002 13 : 109 114.
17. Unemo M, Sjöstrand A, Akhras M, Gharizadeh B, Lindbäck E, Pourmand E, et al. Molecular characterization of Neisseria gonorrhoeae identifies transmission and resistance of one ciprofloxacin resistant strain. APMIS 2007 115 : 231 241.
18. Sarafian SK, Knapp JS. Molecular epidemiology of gonorrhea. Clin Microbiol Rev 1989 2 (Suppl. S49 55.