Increased fetal nuchal translucency thickness and normal karyotype: Prenatal and postnatal follow-up;Translucência nucal aumentada e cariótipo Normal: Evolução pré e pós-natal

Revista da Associacao Medica Brasileira

Volumn 55, Issue 5, 2009, Pages 575-580

  Saldanha, Fátima Aparecida Targino ^a   Brizot, Maria De Lourdes ^a   de Moraes, Edécio Armbruster ^a   Lopes, Lilian M ^a   Zugaib, Marcelo ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Congenital chromosome aberrations; First ultrasonography; Heart defects; Nuchal translucency measurement; Pregnancy trimester

Indexed keywords

EID: 70450175748     PISSN: 01044230     EISSN: None     Source Type: Journal    
DOI: 10.1590/s0104-42302009000500022     Document Type: Article

References (33)

1. Souka AP, Von Kaisenberg CS, Hyett JA, Sonek JD, Nicolaides KH. Increased nuchal translucency with normal Karyotype. Am J Obstet Gynecol. 2005;192:1005-21.
2. Souka A P, Krampl E, Bakalis S, Heath V, Nicolaides KH. Outcome of pregnancy in chromosomally normal fetuses with increased nuchal translucency in the first trimester. Ultrasound Obstet Gynecol. 2001;18:9-17.
3. Bekker MN. A normal 20-week scan of a euploid fetus with a history of first-trimester increased nuchal translucency: caution or reassurance? Opin Ultrasound Obstet Gynecol. 2007;30:8-10.
4. Nicolaides KH, Spencer K, Avgidou K, Faiola S, Falcon O. Multicenter study of first-trimester screening for trisomy 21 in 75.821 pregnancies: results and estimation of the potential impact of individual risk-orientated two-stage first-trimester sceening. Ultrasound Obstet Gynecol. 2005;25:221-6.
5. Brizot ML, Carvalho MHB, Liao AW, Reis SV, Armbruster-Moraes E, Zugaib M. First-trimester screening for chromosomal abnormalities by fetal nuchal translucency in a Brazilian population. Ultrasound Obstet Gynecol. 2001;18:652-5.
6. Bilardo CM, Muller MA, Pajkrt E, Clur SA, Van Zalen MM, Bijlsma EK. Increased nuchal translucency thickness and normal Karyotype: time for parental reassurance. Ultrasound Obstet Gynecol. 2007;30:11-8.
7. th percentile or greater with normal Karyotype: a prospective stdy. Am J Obstet Gynecol. 2007;196:53-6.
8. Brady AF, Pandya PP, Yuksel B, Greenough A, Patton MA, Nicolaides KH. Outcome of chromosomally normal livebirths with increased fetal nuchal translucency at 10 - 14 weeks' gestation. J Med Genet 1998;35:222-4.
9. Van Vugt JMG, Tinnemans BW, Van Zalen-Sprock RM. Outcome and early childhood follow-up of chomosomally normal fetuses with increased nuchal translucency at 10 - 14 week' gestation. Ultrasound Obstet Gynecol. 1998;11:407-9.
10. Adekunle O, Gopee A, El-Sayed M, Thilaganathan B. Increased first trimester nuchal translucency: pregnancy and infant outcomesafter routinescreening for Down's syndrome in an unselected antenatal population. Br J Radiol. 1999;72:457-60.
11. Maymon R, Jauniaux E, Cohen O, Dreazen E, Weinraub Z, Herman A. Pregnancy outcome and infant follou-up of fetuses with abnormally increased first trimester nuchal translucency. Hum Reprod. 2000; 15:2023-7.
12. Hiippala A, Eronen M, Taipale P, Salonen R, Hiilesmaa V. Fetal nuchal translucency and normal chromosomes: a long-term follow-up study. Ultrasound Obstet Gynecol. 2001;18:18-22.
13. Senat MV, De Keersmaecker B, Audibert F, Montcharmont G, Frydman R, Ville Y. Pregnancy outcome in fetuses with increased nuchal translucency and normal Karyotype. Prenat Diagn. 2002;22:345-49.
14. Cheng CC, Bahado-Singh RO, Chen SC, Tsai MS. Pregnancy outcomes with increased nuchal translucency after routine Down syndrome screening. Int J Gynaecol Obstet. 2004;84:5-9.
15. Pandya PP, Kondylios A, Hilbert L, Snijders RJ, Nicolaides KH. Chromosomal defects and outcome in 1015 fetuses with increased nuchal translucency. Ultrasound Obstet Gynecol. 1995;5:15-9.
16. Rezende J. Obstetrícia. 8a ed. Rio de Janeiro: Guanabara Koogan; 1998. Cap.55.
17. th ed. Boston. PWS; 2000.
18. Lopes LM, Brizot ML, Lopes MA, Ayello VD Schultz R, Zugaib M. Structural and functional cardiac abnormalities identified prior to 16 weeks' gestation in fetuses with increased nuchal translucency. Ultrasound Obstet Gynecol. 2003;22:470-8.
19. Bilardo CM, Pajkrt E, Graaf I, Mol BW, Bleker OP. Outcome of fetuses with enlarged nuchal translucency and normal karyotype. Ultrasound Obstet Gyneacol. 1998;11:401-6.
20. Hoffman JIE. Incidence of congenital heart disease: I. Postnatal incidence. Pediatr Cardiol. 1995;16:103-13.
21. Ghi T, Huggon IC, Zosmer N, Nicolaides KH. Incidence of major structural cardiac defects associated with increased nuchal translucency but normal karyotype. Ultrasound Obstet Gynecol. 2001;18:610-4.
22. Hyett J, Perdu M, Sharland G, Snijders RJM, Nicolaides KH. Using fetal nuchal translucency to screen for major congenital cardiac defects at 10-14 weeks of gestation: population based cohort study. BMJ. 1999;318:81-5.
23. McAuliffe F, Winsor S, Hornberger L, Johnson JA. Fetal cardiac defects and increased nuchal translucency thickness: a prospective study. Am J Obstet Gynecol. 2004;191:1486-90.
24. Spencer K, Cowans NJ, Avgidou K, Nicolaides KH. First-trimester ultrasound and biochemical markers of aneuploidy and the prediction of impending fetal death. Ultrasound Obstet Gynecol. 2006;28:637-43.
25. Westin M, Saltvedt S, Almstrom H, Grunewald C, Valentin L. By how much does increased nuchal translucency increased the risk of adverse pregnancy outcome in chromosomally normal fetuses? A study of 16260 fetuses derived from an unselected pregnant population. Ultrasound Obstet Gynecol. 2007;29:150-8.
26. Kypros H. Nicolaides, MD. Nuchal translucency and other first-trimester sonographic markers of chromosomal abnormalities. Am J Obstet Gynecol. 2004;191:45-67.
27. Carvalho MHB, Brizot ML, Lopes LM, Chiba CH, Miyadahira S, Zugaib M Detection of fetal structural abnormalities at the 11 - 14 weeks ultrasound scan. Prenat Diagn. 2002;22:1-4.
28. Snijders RJM, Johnson S, Sebire NJ, Noble PL, Nicilaides KH. First-trimester ultrasound screening for chromosomal defects [Review]. Ultrasound Obstet Gynecol. 1996;7:216-6.
29. Iskaros J, Jauniaux E, Rodeck C. Outcome of nonimmune hidrops fetalis diagnosed during the first half of pregnancy. Obstet Gynecol. 1997;90:321-5.
30. Matias A, Huggon I, Areias JC Montenegro N, Nicolaides KH. Cardiac defects in chromosomally normal fetuses with abnormal ductus venosus blood flow at 10 - 14 weeks. Ultrasound Obstet Gynecol. 1999;14:307-10.
31. Dane B, Dane C, Cetin A, Kiray M, Sivri D, Yayla M. Pregnancy outcome in fetuses with increased nuchal translucency. J Perinatol. 2008;28:400-4.
32. Piazze J, Anceschi MM, Cerekja A, La Torre R, Pala A, Papa A, et al. Nuchal translucency as a predictor of adverse pregnancy outcome. 2007;98:5-9
33. Bilardo CM. Increased nuchal translucency and normal karyotype: coping with uncertainty. Ultrasound Obstet Gynecol. 2001;17:99-101.