Selection for genetic variation inducing pro-inflammatory responses under adverse environmental conditions in a ghanaian population

PLoS ONE

Volumn 4, Issue 11, 2009, Pages

  Kuningas, Maris ^a   May, Linda ^a   Tamm, Riin ^b   van Bodegom, David ^a   van den Biggelaar, Anita H J ^c   Meij, Johannes J ^d   Froölich, Marijke ^a   Ziem, Juventus B ^e   Suchiman, Helena E D ^a   Metspalu, Andres ^b   Slagboom, P Eline ^a,f   Westendorp, Rudi G J ^a,f  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b UNIVERSITY OF TARTU   (Estonia)

^c UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^d Leyden Academy on Vitality and Ageing   (Netherlands)

^e Faculty of Agriculture University for Development Studies   (Ghana)

^f Netherlands Consortium for Healthy Ageing   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

DRINKING WATER; INTERLEUKIN 10; TUMOR NECROSIS FACTOR ALPHA;

ADULT; ARTICLE; CHRONIC INFLAMMATION; CONTROLLED STUDY; FEMALE; GENE LOCUS; GENE SEQUENCE; GENETIC SELECTION; GENETIC VARIABILITY; GENOTYPE; GHANA; HAPLOTYPE; HETEROZYGOTE; HUMAN; INNATE IMMUNITY; MAJOR CLINICAL STUDY; MALE; MORTALITY; SINGLE NUCLEOTIDE POLYMORPHISM; SURVIVAL; AGING; ALLELE; DNA SEQUENCE; ENVIRONMENT; GENETICS; INFLAMMATION; METABOLISM; MOLECULAR GENETICS;

AGING; ALLELES; ENVIRONMENT; GENETIC VARIATION; GENOTYPE; GHANA; HAPLOTYPES; HUMANS; IMMUNITY, INNATE; INFLAMMATION; INTERLEUKIN-10; MOLECULAR SEQUENCE DATA; POLYMORPHISM, SINGLE NUCLEOTIDE; SEQUENCE ANALYSIS, DNA; TUMOR NECROSIS FACTOR-ALPHA;

EID: 70450162305     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0007795     Document Type: Article

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