Dose-dependent osteoinductive effects of bFGF in rabbits

Growth Factors

Volumn 27, Issue 6, 2009, Pages 419-424

  Draenert, G F ^a   Draenert, K ^b   Tischer, T ^c  

^a JOHANNES GUTENBERG UNIVERSITY   (Germany)

^b Center for Orthopaedic Research (ZOW)   (Germany)

^c UNIVERSITY OF MUNICH   (Germany)

Author keywords

Animal model; BFGF; Bone; Histology; Osteoinduction

Indexed keywords

BASIC FIBROBLAST GROWTH FACTOR; BIOMATERIAL; HYDROXYAPATITE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BONE GRAFT; BONE GROWTH; CONTROLLED STUDY; DOSE RESPONSE; HISTOLOGY; MATERIAL COATING; MORPHOMETRICS; NONHUMAN; OSTEOCLAST; PATELLA; PRIORITY JOURNAL; RABBIT; TISSUE INDUCTION;

ANIMALS; BONE REGENERATION; COATED MATERIALS, BIOCOMPATIBLE; DOSE-RESPONSE RELATIONSHIP, DRUG; DURAPATITE; FIBROBLAST GROWTH FACTOR 2; HUMANS; IMPLANTS, EXPERIMENTAL; MODELS, ANIMAL; PATELLA; RABBITS; TREATMENT OUTCOME;

ANIMALIA; ORYCTOLAGUS CUNICULUS;

EID: 70450161130     PISSN: 08977194     EISSN: 10292292     Source Type: Journal    
DOI: 10.3109/08977190903231075     Document Type: Article

References (36)

1. Bostman O, Pihlajamaki H. 2000. Clinical biocompatibility of biodegradable orthopaedic implants for internal fixation: A review. Biomaterials 21:2615-2621, doi: S0142961200001290 [pii].
2. Bush MA, Samara E, Whitehouse MJ, Yoshizawa C, Novicki DL, Pike M, Laham RJ, Simons M, Chronos NA. 2001. Pharmacokinetics and pharmacodynamics of recombinant FGF-2 in a phase I trial in coronary artery disease. J Clin Pharmacol 41:378-385.
3. Chikazu D, Hakeda Y, Ogata N, Nemoto K, Itabashi A, Takato T, Kumegawa M, Nakamura K, Kawaguchi H. 2000. Fibroblast growth factor (FGF)-2 directly stimulates mature osteoclast function through activation of FGF receptor 1 and p42/p44 MAP kinase. J Biol Chem 275:31444-31450, doi: 10.1074/ jbc.M910132199, M910132199 [pii].
4. Chuma H, Mizuta H, Kudo S, Takagi K, Hiraki Y. 2004. One day exposure to FGF-2 was sufficient for the regenerative repair of full-thickness defects of articular cartilage in rabbits. Osteoarthritis Cartilage 12:834-842, doi: 10.1016/j.joca.2004.07.003, S1063-4584(04)00137-142 [pii].
5. Cuevas P, Carceller F, Ortega S, Zazo M, Nieto I, Gimenez-Gallego G. 1991. Hypotensive activity of fibroblast growth factor. Science 254:1208-1210.
6. Draenert K. 1982. Stable fixed autologous and homologous cancellous bone transplants. In: Hackbroch MH, Refior HJ, Jaeger M, editors. Osteogenesis and bone growth. New York, NY: Thieme Publisher. p 177-184.
7. Draenert GF, Delius M. 2007. The mechanically stable steam sterilization of bone grafts. Biomaterials 28:1531-1538, doi: S0142-9612(06)00995-1001 [pii], 10.1016/j.biomaterials.2006.11.029. (Pubitemid 46027251)
8. Dunstan CR, Boyce R, Boyce BF, Garrett IR, Izbicka E, Burgess WH, Mundy GR. 1999. Systemic administration of acidic fibroblast growth factor (FGF-1) prevents bone loss and increases new bone formation in ovariectomized rats. J Bone Miner Res 14:953-959.
9. Enlow DH. 1963. The Canal system in bone. In: Enlow DH, editor. Principles of bone remodelling. Springfield, IL: Charles C Thomas Publisher. p 60-74.
10. Frost HM, Vilanueva AR, Jett S, Eyring E. 1969. Tetracycline-based analysis of bone remodelling in osteopetrosis. Clin Orthop Relat Res 65:203-217.
11. Harris WH. 1960. A microscopic method of determining rates of bone growth. Nature 188:1038-1039.
12. Ifkovits JL, Burdick JA. 2007. Review: Photopolymerizable and degradable biomaterials for tissue engineering applications. Tissue Eng 13:2369-2385, doi: 10.1089/ten.2007.0093. (Pubitemid 47571700)
13. Inoue Y, King TE, Jr, Barker E, Daniloff E, Newman LS. 2002. Basic fibroblast growth factor and its receptors in idiopathic pulmonary fibrosis and lymphangioleiomyomatosis. Am J Respir Crit Care Med 166:765-773.
14. Kawaguchi H, Jingushi S, Izumi T, Fukunaga M, Matsushita T, Nakamura T, Mizuno K, Nakamura K. 2007. Local application of recombinant human fibroblast growth factor-2 on bone repair: A dose-escalation prospective trial on patients with osteotomy. J Orthop Res 25:480-487, doi: 10.1002/jor.20315. (Pubitemid 46542035)
15. Klagsbrun M. 1992. Mediators of angiogenesis: The biological significance of basic fibroblast growth factor (bFGF)-heparin and heparan sulfate interactions. Semin Cancer Biol 3:81-87.
16. Kofron MD, Li X, Laurencin CT. 2004. Protein- and gene-based tissue engineering in bone repair. Curr Opin Biotechnol 15: 399-405, doi: S0958-1669(04)00103-X [pii], 10.1016/j.copbio. 2004.07.004.
17. Komaki H, Tanaka T, Chazono M, Kikuchi T. 2006. Repair of segmental bone defects in rabbit tibiae using a complex of betatricalcium phosphate, type I collagen, and fibroblast growth factor-2. Biomaterials 27:5118-5126, doi: S0142- 9612(06)00459-5 [pii], 10.1016/j.biomaterials.2006.05.031. (Pubitemid 43928123)
18. Kuroda S, Kasugai S, Oida S, Iimura T, Ohya K, Ohyama T. 1999. Anabolic effect of aminoterminally truncated fibroblast growth factor 4 (FGF4) on bone. Bone 25:431-437, doi: S8756- 3282(99)00193-3 [pii].
19. Lee JY, Choo JE, Choi YS, Lee KY,Min DS, Pi SH, Seol YJ, Lee SJ, Jo IH, Chung CP, Park YJ. 2007. Characterization of the surface immobilized synthetic heparin binding domain derived from human fibroblast growth factor-2 and its effect on osteoblast differentiation. J Biomed Mater Res A 83:970-979, doi: 10.1002/jbm.a.31351. (Pubitemid 350231757)
20. Mayahara H, Ito T, Nagai H, Miyajima H, Tsukuda R, Taketomi S, Mizoguchi J, Kato K. 1993. In vivo stimulation of endosteal bone formation by basic fibroblast growth factor in rats. Growth Factors 9:73-80.
21. Miller ED, Fisher GW,Weiss LE,Walker LM, Campbell PG. 2006. Dose-dependent cell growth in response to concentration modulated patterns of FGF-2 printed on fibrin. Biomaterials 27:2213-2221, doi: S0142-9612(05)01002- 1011 [pii], 10.1016/ j.biomaterials.2005.10.021.
22. Nunamaker DM. 1998. Experimental models of fracture repair. Clin Orthop Relat Res 355:S56-S65.
23. O'Loughlin PF, Morr S, Bogunovic L, Kim AD, Park B, Lane JM. 2008. Selection and development of preclinical models in fracture-healing research. J Bone Joint Surg Am 90(Suppl 1): 79-84, doi: 90/Supplement-1/79 [pii], 10.2106/JBJS.G.01585. (Pubitemid 351329125)
24. Olsen SK, Ibrahimi OA, Raucci A, Zhang F, Eliseenkova AV, Yayon A, Basilico C, Linhardt RJ, Schlessinger J, Mohammadi M. 2004. Insights into the molecular basis for fibroblast growth factor receptor autoinhibition and ligand-binding promiscuity. Proc Natl Acad Sci USA 101:935-940, doi: 10.1073/pnas.0307287101, 0307287101 [pii].
25. Park J, Lutz R, Felszeghy E, Wiltfang J, Nkenke E, Neukam FW, Schlegel KA. 2007. The effect on bone regeneration of a liposomal vector to deliver BMP-2 gene to bone grafts in periimplant bone defects. Biomaterials 28:2772-2782, doi: S0142- 9612(07)00147-0 [pii], 10.1016/j.biomaterials.2007.02.009. (Pubitemid 46415761)
26. Pezzatini S, Morbidelli L, Solito R, Paccagnini E, Boanini E, Bigi A, Ziche M. 2007. Nanostructured HA crystals up-regulate FGF-2 expression and activity in microvascular endothelium promoting angiogenesis. Bone 41:523-534, doi: S8756-3282(07)00540-546 [pii], 10.1016/j.bone.2007.06.016. (Pubitemid 47385437)
27. Quarto N, Fong KD, Longaker MT. 2005. Gene profiling of cells expressing different FGF-2 forms. Gene 356:49-68, doi: S0378-1119(05)00256-258 [pii], 10.1016/j.gene.2005.05.014. (Pubitemid 41175971)
28. Sailhan F, Chotel F, Chousta A, Viguier E, Boivin G. 2007. Unexpected absence of effect of rhBMP-7 on distraction osteogenesis. Clin Orthop Relat Res 457:227-234, doi: 10.1097/BLO.0b013e31802f1973. (Pubitemid 46573420)
29. Thoren K, Aspenberg P. 1993. Effects of basic fibroblast growth factor on bone allografts. A study using bone harvest chambers in rabbits. Ann Chir Gynaecol Suppl 207:129-135.
30. Urist M.R. 1965. Bone: Formation by autoinduction. Science 150: 893-899.
31. Wang JS, Aspenberg P. 1993. Basic fibroblast growth factor and bone induction in rats. Acta Orthop Scand 64:557-561.
32. Warren SM, Fong KD, Chen CM, Loboa EG, Cowan CM, Lorenz HP, Longaker MT. 2003. Tools and techniques for craniofacial tissue engineering. Tissue Eng 9:187-200, doi: 10.1089/ 107632703764664666. (Pubitemid 36944169)
33. Weiss S, Baumgart R, Jochum M, Strasburger CJ, Bidlingmaier M. 2002. Systemic regulation of distraction osteogenesis: A cascade of biochemical factors. J Bone Miner Res 17:1280-1289.
34. Winet H, Bao JY. 1998. Fibroblast growth factor-2 alters the effect of eroding polylactide-polyglycolide on osteogenesis in the bone chamber. J Biomed Mater Res 40:567-576, doi: 10.1002/ (SICI)1097-4636(19980615)40:4,567::AID-JBM8. 3.0.CO; 2-D [pii].
35. Yamada K, Tabata Y, Yamamoto K, Miyamoto S, Nagata I, Kikuchi H, Ikada Y. 1997. Potential efficacy of basic fibroblast growth factor incorporated in biodegradable hydrogels for skull bone regeneration. J Neurosurg 86:871-875.
36. Yu PJ, Ferrari G, Galloway AC, Mignatti P, Pintucci G. 2007. Basic fibroblast growth factor (FGF-2): The high molecular weight forms come of age. J Cell Biochem 100:1100-1108, doi: 10.1002/jcb.21116. (Pubitemid 46480393)