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Volumn 24, Issue 6, 2009, Pages 523-535

A mathematical model of homeostatic regulation of sleep-wake cycles by hypocretin/orexin

Author keywords

Hypocretin; Lateral hypothalamus; Orexin; Reciprocal excitation; Sleep homeostasis; Synaptic plasticity

Indexed keywords

GLUTAMIC ACID; NEUROPEPTIDE; OREXIN;

EID: 70450160493     PISSN: 07487304     EISSN: 15524531     Source Type: Journal    
DOI: 10.1177/0748730409346655     Document Type: Article
Times cited : (36)

References (49)
  • 1
    • 84871886186 scopus 로고    scopus 로고
    • The two-process model of sleep regulation revisited
    • Achermann P. (2004) The two-process model of sleep regulation revisited. Aviat Space Environ Med 75 (3). A37 - A43.
    • (2004) Aviat Space Environ Med , vol.75 , Issue.3
    • Achermann, P.1
  • 2
    • 0036092643 scopus 로고    scopus 로고
    • Invited review: Regulation of mammalian circadian clock genes
    • Albrecht U. (2002) Invited review: regulation of mammalian circadian clock genes. J Appl Physiol 92: 1348-1355.
    • (2002) J Appl Physiol , vol.92 , pp. 1348-1355
    • Albrecht, U.1
  • 4
    • 0036813717 scopus 로고    scopus 로고
    • Model of thalamocortical slow-wave sleep oscillations and transitions to activated states
    • Bazhenov M., Timofeev I., Steriade M., and Sejnowski TJ (2002) Model of thalamocortical slow-wave sleep oscillations and transitions to activated states. J Neurosci 22: 8691-8704.
    • (2002) J Neurosci , vol.22 , pp. 8691-8704
    • Bazhenov, M.1    Timofeev, I.2    Steriade, M.3    Sejnowski, T.J.4
  • 5
    • 34249106123 scopus 로고    scopus 로고
    • Neuronal models for sleep-wake regulation and synaptic reorganization in the sleeping hippocampus
    • Best J., Diniz Behn CG, Poe GR, and Booth V. (2007) Neuronal models for sleep-wake regulation and synaptic reorganization in the sleeping hippocampus. J Biol Rhythms 22 (3). 220-232.
    • (2007) J Biol Rhythms , vol.22 , Issue.3 , pp. 220-232
    • Best, J.1    Diniz Behn, C.G.2    Poe, G.R.3    Booth, V.4
  • 6
    • 0020368354 scopus 로고
    • A two process model of sleep regulation
    • BorbÉly AA (1982) A two process model of sleep regulation. Hum Neurobiol 1: 195-204.
    • (1982) Hum Neurobiol , vol.1 , pp. 195-204
    • Borbély, A.A.1
  • 7
    • 0033367369 scopus 로고    scopus 로고
    • Sleep homeostasis and models of sleep regulation
    • Borbély AA and Achermann P. (1999) Sleep homeostasis and models of sleep regulation. J Biol Rhythms 14: 557-568.
    • (1999) J Biol Rhythms , vol.14 , pp. 557-568
    • Borbély, A.A.1    Achermann, P.2
  • 10
    • 0001859405 scopus 로고
    • Timing of human sleep: Recovery process gated by a circadian pacemaker
    • Daan S., Beersma DG, and BorbÉly AA (1984) Timing of human sleep: recovery process gated by a circadian pacemaker. Am J Physiol 246: R161 - R178.
    • (1984) Am J Physiol , vol.246
    • Daan, S.1    Beersma, D.G.2    Borbély, A.A.3
  • 11
    • 37549069954 scopus 로고    scopus 로고
    • Systemic and nasal delivery of orexin-A (hypocretin-1) reduces the effects of sleep deprivation on cognitive performance in nonhuman primates
    • Deadwyler SA, Porrino L., Siegel JM, and Hampson RE (2007) Systemic and nasal delivery of orexin-A (hypocretin-1) reduces the effects of sleep deprivation on cognitive performance in nonhuman primates. J Neurosci 27 (52). 14239-14247.
    • (2007) J Neurosci , vol.27 , Issue.52 , pp. 14239-14247
    • Deadwyler, S.A.1    Porrino, L.2    Siegel, J.M.3    Hampson, R.E.4
  • 12
    • 34248999234 scopus 로고    scopus 로고
    • Mathematical model of network dynamics governing mouse sleep-wake behavior
    • Diniz Behn CG, Brown EN, Scammell TE, and Kopell NJ (2007) Mathematical model of network dynamics governing mouse sleep-wake behavior. J Neurophysiol 97 (6). 3828-3840.
    • (2007) J Neurophysiol , vol.97 , Issue.6 , pp. 3828-3840
    • Diniz Behn, C.G.1    Brown, E.N.2    Scammell, T.E.3    Kopell, N.J.4
  • 14
    • 57049126603 scopus 로고    scopus 로고
    • Delayed orexin signaling consolidates wakefulness and sleep: Physiology and modeling
    • Diniz Behn CG, Kopell N., Brown EN, Mochizuki T., and Scammell TE (2008) Delayed orexin signaling consolidates wakefulness and sleep: physiology and modeling. J Neurophysiol 99: 3090-3103.
    • (2008) J Neurophysiol , vol.99 , pp. 3090-3103
    • Diniz Behn, C.G.1    Kopell, N.2    Brown, E.N.3    Mochizuki, T.4    Scammell, T.E.5
  • 15
    • 36849087097 scopus 로고    scopus 로고
    • Sleep homeostasis and cortical synchronization: I. Modeling the effects of synaptic strength on sleep slow waves
    • Esser SK, Hill SL, and Tononi G. (2007) Sleep homeostasis and cortical synchronization: I. Modeling the effects of synaptic strength on sleep slow waves. Sleep 30: 1617-1630. (Pubitemid 350234741)
    • (2007) Sleep , vol.30 , Issue.12 , pp. 1617-1630
    • Esser, S.K.1    Hill, S.L.2    Tononi, G.3
  • 16
    • 47549118840 scopus 로고    scopus 로고
    • Propagation effects of current and conductance noise in a model neuron with subthreshold oscillations
    • Finke C., Vollmer J., Postnova S., and Braun HA (2008) Propagation effects of current and conductance noise in a model neuron with subthreshold oscillations. Math Biosci 214 (1-2). 109-121.
    • (2008) Math Biosci , vol.214 , Issue.1-2 , pp. 109-121
    • Finke, C.1    Vollmer, J.2    Postnova, S.3    Braun, H.A.4
  • 17
    • 0035901736 scopus 로고    scopus 로고
    • Changes in CSF hypocretin-1 (orexin A) levels in rats across 24 hours and in response to food deprivation
    • Fujiki N., Yoshida Y., Ripley B., Honda K., Mignot E., and Nishino S. (2001) Changes in CSF hypocretin-1 (orexin A) levels in rats across 24 hours and in response to food deprivation. Neuroreport 12 (5). 993-997.
    • (2001) Neuroreport , vol.12 , Issue.5 , pp. 993-997
    • Fujiki, N.1    Yoshida, Y.2    Ripley, B.3    Honda, K.4    Mignot, E.5    Nishino, S.6
  • 19
    • 0032242758 scopus 로고    scopus 로고
    • Clock controls circadian period in isolated suprachiasmatic nucleus neurons
    • Herzog ED, Takahashi JS, and Block GD (1998) Clock controls circadian period in isolated suprachiasmatic nucleus neurons. Nature Neurosci 1: 708-713.
    • (1998) Nature Neurosci , vol.1 , pp. 708-713
    • Herzog, E.D.1    Takahashi, J.S.2    Block, G.D.3
  • 20
    • 14144255233 scopus 로고    scopus 로고
    • Modeling sleep and wakefulness in the thalamocortical system
    • Hill S. and Tononi G. (2005) Modeling sleep and wakefulness in the thalamocortical system. J Neurophysiol 93: 1671-1698.
    • (2005) J Neurophysiol , vol.93 , pp. 1671-1698
    • Hill, S.1    Tononi, G.2
  • 22
    • 0033550889 scopus 로고    scopus 로고
    • Effect of lateral cerebroventricular injection of the appetite-stimulating neuropeptide, orexin and neuropeptide Y, on the various behavioral activities of rats
    • Ida T., Nakahara K., Katayama T., Murakami N., and Nakazato M. (1999) Effect of lateral cerebroventricular injection of the appetite-stimulating neuropeptide, orexin and neuropeptide Y, on the various behavioral activities of rats. Brain Res 821: 526-529.
    • (1999) Brain Res , vol.821 , pp. 526-529
    • Ida, T.1    Nakahara, K.2    Katayama, T.3    Murakami, N.4    Nakazato, M.5
  • 23
    • 0002580602 scopus 로고
    • Arousal, emotion, and behavioral homeostasis
    • Kandel ER, Scwartz JH, and Jessell TM, eds, New York, McGraw-Hill.
    • Kandel ER, Scwartz JH, and Jessell TM (1991) Arousal, emotion, and behavioral homeostasis. In Principles of Neural Science, Kandel ER, Scwartz JH, and Jessell TM, eds, pp 869-1014, New York, McGraw-Hill.
    • (1991) Principles of Neural Science , pp. 869-1014
    • Kandel, E.R.1    Scwartz, J.H.2    Jessell, T.M.3
  • 24
    • 43049139109 scopus 로고    scopus 로고
    • Sleep homeostasis: A role for adenosine in humans
    • Landolt HP (2008) Sleep homeostasis: a role for adenosine in humans ? Biochem Pharmacol 75 (11). 2070-2079.
    • (2008) Biochem Pharmacol , vol.75 , Issue.11 , pp. 2070-2079
    • Landolt, H.P.1
  • 25
    • 22244443005 scopus 로고    scopus 로고
    • Discharge of identified orexin/hypocretin neurons across the sleep-waking cycle
    • Lee MG, Hassani OK, and Jones BE (2005) Discharge of identified orexin/hypocretin neurons across the sleep-waking cycle. J Neurosci 25 (28). 6716-6720.
    • (2005) J Neurosci , vol.25 , Issue.28 , pp. 6716-6720
    • Lee, M.G.1    Hassani, O.K.2    Jones, B.E.3
  • 26
    • 0037137682 scopus 로고    scopus 로고
    • Hypocretin/orexin excites hypocretin neurons via a local glutamate neuron-A potential mechanism for orchestrating the hypothalamic arousal system
    • Li Y., Gao XB, Sakurai T., and van den Pol AN (2002) Hypocretin/orexin excites hypocretin neurons via a local glutamate neuron-A potential mechanism for orchestrating the hypothalamic arousal system. Neuron 36: 1169-1181.
    • (2002) Neuron , vol.36 , pp. 1169-1181
    • Li, Y.1    Gao, X.B.2    Sakurai, T.3    Van Den Pol, A.N.4
  • 27
    • 0033529520 scopus 로고    scopus 로고
    • The sleep disorder canine narcolepsy is caused by a mutation in the hypocretin (orexin) receptor 2 gene
    • Lin L., Faraco J., Li R., Kadotani H., Rogers W., Lin X., Qiu X., de Jong PJ, Nishino S., and Mignot E. (1999) The sleep disorder canine narcolepsy is caused by a mutation in the hypocretin (orexin) receptor 2 gene. Cell 98 (3). 365-376.
    • (1999) Cell , vol.98 , Issue.3 , pp. 365-376
    • Lin, L.1    Faraco, J.2    Li, R.3    Kadotani, H.4    Rogers, W.5    Lin, X.6    Qiu, X.7    De Jong, P.J.8    Nishino, S.9    Mignot, E.10
  • 28
    • 19544376694 scopus 로고    scopus 로고
    • Behavioral correlates of activity in identified hypocretin/orexin neurons
    • Mileykovskiy BY, Kiyashchenko LI, and Siegel JM (2005) Behavioral correlates of activity in identified hypocretin/orexin neurons. Neuron 46: 787-798.
    • (2005) Neuron , vol.46 , pp. 787-798
    • Mileykovskiy, B.Y.1    Kiyashchenko, L.I.2    Siegel, J.M.3
  • 29
    • 27544497028 scopus 로고    scopus 로고
    • Circadian regulation of sleep in mammals: Role of the suprachiasmatic nucleus
    • Mistlberger RE (2005) Circadian regulation of sleep in mammals: role of the suprachiasmatic nucleus. Brain Res Rev 49: 429-454.
    • (2005) Brain Res Rev , vol.49 , pp. 429-454
    • Mistlberger, R.E.1
  • 31
    • 36248992915 scopus 로고    scopus 로고
    • Suprachiasmatic nucleus in sleep-wake regulation
    • Moore RY (2007) Suprachiasmatic nucleus in sleep-wake regulation. Sleep Med 8 (3). 27-33.
    • (2007) Sleep Med , vol.8 , Issue.3 , pp. 27-33
    • Moore, R.Y.1
  • 32
    • 0033971611 scopus 로고    scopus 로고
    • Hypocretin (orexin) deficiency in human narcolepsy
    • Nishino S., Ripley B., Overeem S., Lammers GJ, and Mignot E. (2000) Hypocretin (orexin) deficiency in human narcolepsy. Lancet 355 (9197). 39-40.
    • (2000) Lancet , vol.355 , Issue.9197 , pp. 39-40
    • Nishino, S.1    Ripley, B.2    Overeem, S.3    Lammers, G.J.4    Mignot, E.5
  • 34
    • 34147110249 scopus 로고    scopus 로고
    • A quantitative model of sleep-wake dynamics based on the physiology of the brainstem ascending arousal system
    • Phillips AJK and Robinson PA (2007) A quantitative model of sleep-wake dynamics based on the physiology of the brainstem ascending arousal system. J Biol Rhythms 22: 167-179.
    • (2007) J Biol Rhythms , vol.22 , pp. 167-179
    • Ajk, P.1    Robinson, P.A.2
  • 36
    • 33847121297 scopus 로고    scopus 로고
    • The neural circuit of orexin (hypocretin): Maintaining sleep and wakefulness
    • Sakurai T. (2007) The neural circuit of orexin (hypocretin). maintaining sleep and wakefulness. Nat Rev Neurosci 8: 171-181.
    • (2007) Nat Rev Neurosci , vol.8 , pp. 171-181
    • Sakurai, T.1
  • 39
    • 27644457084 scopus 로고    scopus 로고
    • Hypothalamic regulation of sleep and circadian rhythms
    • DOI 10.1038/nature04284, PII N04284
    • Saper CB, Scammell TE, and Lu J. (2005) Hypothalamic regulation of sleep and circadian rhythms. Nature 437 (27). 1257-1263. (Pubitemid 41568665)
    • (2005) Nature , vol.437 , Issue.7063 , pp. 1257-1263
    • Saper, C.B.1    Scammell, T.E.2    Lu, J.3
  • 40
    • 0029671044 scopus 로고    scopus 로고
    • Activation of ventrolateral preoptic neurons during sleep
    • Sherin JE, Shiromani PJ, McCarley RW, and Saper CB (1996) Activation of ventrolateral preoptic neurons during sleep. Science 271: 216-219.
    • (1996) Science , vol.271 , pp. 216-219
    • Sherin, J.E.1    Shiromani, P.J.2    McCarley, R.W.3    Saper, C.B.4
  • 42
    • 0036580756 scopus 로고    scopus 로고
    • The hypocretins: Setting the arousal threshold
    • Sutcliffe JG and de Lecea L. (2002) The hypocretins: setting the arousal threshold. Nat Rev Neurosci 3 (5). 339-349.
    • (2002) Nat Rev Neurosci , vol.3 , Issue.5 , pp. 339-349
    • Sutcliffe, J.G.1    De Lecea, L.2
  • 43
    • 33646179187 scopus 로고    scopus 로고
    • A quartet neural system model orchestrating sleep and wakefulness mechanisms
    • Tamakawa Y., Karashima A., Koyama Y., Katayama N., and Nakao M. (2007) A quartet neural system model orchestrating sleep and wakefulness mechanisms. J Neurophysiol 95: 2055-2069.
    • (2007) J Neurophysiol , vol.95 , pp. 2055-2069
    • Tamakawa, Y.1    Karashima, A.2    Koyama, Y.3    Katayama, N.4    Nakao, M.5
  • 46
    • 30844435916 scopus 로고    scopus 로고
    • Sleep function and synaptic homeostasis
    • Tononi G. and Cirelli C. (2006) Sleep function and synaptic homeostasis. Sleep Med Rev 10 (1). 49-62.
    • (2006) Sleep Med Rev , vol.10 , Issue.1 , pp. 49-62
    • Tononi, G.1    Cirelli, C.2
  • 49
    • 0037509933 scopus 로고    scopus 로고
    • Circadian and homeostatic regulation of hypocretin in a primate model: Implications for the consolidation of wakefulness
    • Zeitzer JM, Buckmaster CL, Parker KJ, Hauck CM, Lyons DM, and Mignot E. (2003) Circadian and homeostatic regulation of hypocretin in a primate model: implications for the consolidation of wakefulness. J Neurosci 23 (8). 3555-3560.
    • (2003) J Neurosci , vol.23 , Issue.8 , pp. 3555-3560
    • Zeitzer, J.M.1    Buckmaster, C.L.2    Parker, K.J.3    Hauck, C.M.4    Lyons, D.M.5    Mignot, E.6


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