Handedness does not predict side of onset of motor symptoms in Parkinson's disease

Movement Disorders

Volumn 24, Issue 12, 2009, Pages 1836-1839

  Štochl, Jan ^a   Hagtvet, Knut A ^b   Brožová, Hana ^a   Klempíř, Jiří ^a   Roth, Jan ^a   Růžička, Evžen ^a  

^a CHARLES UNIVERSITY   (Czech Republic)

^b UNIVERSITY OF OSLO   (Norway)

Author keywords

Asymmetry; Handedness; Laterality; Motor symptoms; Parkinson's disease

Indexed keywords

AGED; ARTICLE; BRAIN ASYMMETRY; CONTROLLED STUDY; FEMALE; HANDEDNESS; HUMAN; LEFT HANDEDNESS; MAJOR CLINICAL STUDY; MALE; MATHEMATICAL MODEL; MOTOR DYSFUNCTION; PARKINSON DISEASE; PREDICTION; PRIORITY JOURNAL; QUESTIONNAIRE; RIGHT HANDEDNESS; SYMPTOM;

AGE OF ONSET; AGED; BEHAVIORAL SYMPTOMS; CHI-SQUARE DISTRIBUTION; DISABILITY EVALUATION; FEMALE; FUNCTIONAL LATERALITY; HUMANS; MALE; MIDDLE AGED; MOTOR ACTIVITY; PARKINSONIAN DISORDERS; PREDICTIVE VALUE OF TESTS; PSYCHIATRIC STATUS RATING SCALES; QUESTIONNAIRES; RETROSPECTIVE STUDIES; STATISTICS, NONPARAMETRIC;

EID: 70449985716     PISSN: 08853185     EISSN: 15318257     Source Type: Journal    
DOI: 10.1002/mds.22653     Document Type: Article

References (20)

1. Stebbins GT, Goetz CG. Factor structure of the Unified Parkinson's Disease Rating Scale: motor examination section. Mov Disord 1998;13:633-636.
2. Stebbins GT, Goetz CG, Lang AE, Cubo E. Factor analysis of the motor section of the Unified Parkinson's Disease Rating Scale during the off-state. Mov Disord 1999;14:585-589. (Pubitemid 30011450)
3. Štochl J, Boomsma A, Růžička E, Brožová H, Blahuš P. On the structure of motor symptoms of Parkinson's disease. Mov Disord 2008;23:1307-1312.
4. Djaldetti R, Ziv I, Melamed E. The mystery of motor asymmetry in Parkinson's disease. Lancet Neurol 2006;5:796-802. (Pubitemid 44205516)
5. Fahn S, Elton RL. Unified Parkinson's Disease Rating Scale. In: Fahn S, Marsden CD, Calne D, Goldstein M, editors. Recent developments in Parkinson's disease. Floral Park, NY: MacMillan Healthcare Information; 1987. p 153-163.
6. Lee CS, Schulzer M, Mak E, Hammerstad JP, Calne S, Calne DB. Patterns of asymmetry do not change over the course of idiopathic parkinsonism: implications for pathogenesis. Neurology 1995;45(3, Part 1):435-439.
7. Kempster PA, Gibb WR, Stern GM, Lees AJ. Asymmetry of substantia nigra neuronal loss in Parkinson's disease and its relevance to the mechanism of levodopa related motor fluctuations. J Neurol Neurosurg Psychiatry 1989;52:72-76.
8. Kumakura Y, Gjedde A, Danielsen EH, Christensen S, Cumming P. Dopamine storage capacity in caudate and putamen of patients with early Parkinson's isease: correlation with asymmetry of motor symptoms. J Cereb Blood Flow Metab 2006;26:358-370. (Pubitemid 43297917)
9. Hughes AJ,Daniel SE, Kilford L, LeesAJ. Accuracy of clinical diagnosis of idiopathic Parkinson's disease: a clinico-pathological study of 100 cases. J Neurol Neurosurg Psychiatry 1992;55:181-184.
10. Litvan I, MacIntyre A, Goetz CG, et al. Accuracy of the clinical diagnoses of Lewy body disease, Parkinson disease, and dementia with Lewy bodies: a clinicopathologic study. Arch Neurol 1998;55:969-978.
11. Kim SG, Ashe J, Hendrich K, et al. Functional magnetic resonance imaging of motor cortex: hemispheric asymmetry and handedness. Science 1993;261:615-617. (Pubitemid 23278374) (Pubitemid 23982802)
12. Reynolds LM, Locke S. Relation between handedness and side of onset of Parkinsonism. Lancet 1971;2:714.
13. Klawans HL, Jr. Relationship between handedness and side of onset of parkinsonism. Lancet 1972;1:850.
14. Uitti RJ, Baba Y, Whaley NR, Wszolek ZK, Putzke JD. Parkinson disease: handedness predicts asymmetry. Neurology 2005;64:1925-1930. (Pubitemid 40800708)
15. Poewe WH, Wenning GK. The natural history of Parkinson's disease. Ann Neurol 1998;44(3, Suppl 1):S1-S9.
16. Yust-Katz S, Tesler D, Treves T, Melamed E, Djaldetti R. Handedness as a predictor of side of onset of Parkinson's disease. Parkinsonism Relat Disord 2008;14:633-635.
17. Cohen AD, Tillerson JL, Smith AD, Schallert T, Zigmond MJ. Neuroprotective effects of prior limb use in 6-hydroxydopaminetreated rats: possible role of GDNF. J Neurochem 2003;85:299-305. (Pubitemid 36438326)
18. Oldfield RC. The assessment and analysis of handedness: the Edinburgh inventory. Neuropsychologia 1971;9:97-114.
19. Annett M. A classification of hand preference by association analysis. Brit J Psychol 1970;61:303-321.
20. Jöreskog KG, Sörbom D. LISREL 8.72. Lincolnwood, IL: Scientific Software International; 2005.