Raspberry-like assembly of cross-linked nanogels for protein delivery

Journal of Controlled Release

Volumn 140, Issue 3, 2009, Pages 312-317

  Hasegawa, Urara ^a   Sawada, Shin ichi ^a   Shimizu, Takeshi ^b   Kishida, Tsunao ^b   Otsuji, Eigo ^b   Mazda, Osam ^b   Akiyoshi, Kazunari ^a  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^b KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

Author keywords

IL 12; Nanogel; Polysaccharide; Protein delivery; Sustained release

Indexed keywords

ACRYLATE GROUPS; CONCENTRATION OF; HIGH POTENTIAL; IL-12; INTERLEUKIN-12; MICHAEL ADDITIONS; NANOGELS; NARROW SIZE DISTRIBUTIONS; PHYSIOLOGICAL CONDITION; PROTEIN DELIVERY; PULLULANS; SUSTAINED RELEASE; THIOL GROUPS;

ADDITION REACTIONS; ETHYLENE; ETHYLENE GLYCOL; FLUORINE CONTAINING POLYMERS; POLYETHYLENE GLYCOLS; POLYETHYLENE OXIDES; POLYSACCHARIDES; PROTEINS;

NANOSTRUCTURED MATERIALS;

ACRYLIC ACID; BOVINE SERUM ALBUMIN; CHOLESTEROL BEARING PULLULAN NANOGEL; MACROGOL; NANOCARRIER; RECOMBINANT INTERLEUKIN 12; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CHEMICAL MODIFICATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CROSS LINKING; DRUG BLOOD LEVEL; DRUG DEGRADATION; DRUG STABILITY; DRUG STRUCTURE; HYDROLYSIS; MOUSE; NANOENCAPSULATION; NANOMEDICINE; NONHUMAN; PARTICLE SIZE; PRIORITY JOURNAL;

ACRYLATES; ANIMALS; CHOLESTEROL; CROSS-LINKING REAGENTS; DRUG COMPOUNDING; DRUG DELIVERY SYSTEMS; GLUCANS; HYDROGEN-ION CONCENTRATION; INTERLEUKIN-12; LIGHT; MICE; MICROSCOPY, ATOMIC FORCE; MICROSCOPY, ELECTRON, TRANSMISSION; POLYETHYLENE GLYCOLS; PROTEINS; SCATTERING, RADIATION;

EID: 70449729646     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2009.06.025     Document Type: Article

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