Agar-gelatin hybrid sponge-induced three-dimensional in vitro 'liver-like' HepG2 spheroids for the evaluation of drug cytotoxicity

Journal of Tissue Engineering and Regenerative Medicine

Volumn 3, Issue 5, 2009, Pages 368-376

  Verma, Poonam ^a,b   Verma, Vipin ^a,b   Ray, Pratima ^b   Ray, Alok R ^a,b  

^a INDIAN INSTITUTE OF TECHNOLOGY DELHI   (India)

^b ALL INDIA INSTITUTE OF MEDICAL SCIENCES   (India)

Author keywords

Drug cytotoxicity; HepG2 cells; Paracetamol; Scaffolds; Three dimensional cell culture; Tissue engineering

Indexed keywords

ALGAE; CELL CULTURE; CELL ENGINEERING; CELLS; CONTROLLED DRUG DELIVERY; GROWTH KINETICS; METABOLISM; MONOLAYERS; POLYSACCHARIDES; SCAFFOLDS (BIOLOGY); UREA;

CELL-ADHESIVE PROPERTIES; DRUG CYTOTOXICITY; HEP-G2 CELLS; HYBRID SPONGES; IN-VITRO; PARACETAMOL; THREE DIMENSIONAL CELL CULTURE; TISSUES ENGINEERINGS; UREA SYNTHESIS; VITRO LIVER;

CYTOTOXICITY;

AGAR GELATIN HYBRID SPONGE; ALBUMIN; MOLECULAR SCAFFOLD; PARACETAMOL; UNCLASSIFIED DRUG; UREA; AGAR; ALBUMINOID; ANALGESIC AGENT; GELATIN;

ARTICLE; CELL ADHESION; CELL FUNCTION; CELL PROLIFERATION; CELL STRAIN HEPG2; CELL STRUCTURE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY TEST; DRUG CYTOTOXICITY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN SECRETION; SPHEROID CELL; UREA CYCLE; CELL LINE; CHEMISTRY; CULTURE TECHNIQUE; DRUG SCREENING; GENE EXPRESSION REGULATION; IC 50; KINETICS; LIVER; METABOLISM; METHODOLOGY; MICROSCOPY; PATHOLOGY;

ACETAMINOPHEN; AGAR; ALBUMINS; ANALGESICS, NON-NARCOTIC; CELL CULTURE TECHNIQUES; CELL LINE; DRUG EVALUATION, PRECLINICAL; GELATIN; GENE EXPRESSION REGULATION; HUMANS; INHIBITORY CONCENTRATION 50; KINETICS; LIVER; MICROSCOPY; UREA;

EID: 70449717681     PISSN: 19326254     EISSN: 19327005     Source Type: Journal    
DOI: 10.1002/term.172     Document Type: Article

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