The PFKFB3 splice variant UBI2K4 is downregulated in high-grade astrocytomas and impedes the growth of U87 glioblastoma cells

Neuropathology and Applied Neurobiology

Volumn 35, Issue 6, 2009, Pages 566-578

  Zscharnack, K ^a   Kessler, R ^a   Bleichert, F ^a,b   Warnke, J P ^c   Eschrich, K ^a  

^a UNIVERSITY OF LEIPZIG   (Germany)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c Paracelsus Hospital   (Germany)

Author keywords

Alternative splicing; Astrocytoma; Glycolysis; IPFK 2; PFKFB3

Indexed keywords

ISOENZYME; MESSENGER RNA; PFKFB3 PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; ASTROCYTOMA; CANCER INHIBITION; CELL ANCHORAGE; CELL COUNT; CELL GROWTH; CELL VIABILITY; CLINICAL ARTICLE; CONTROLLED STUDY; DOWN REGULATION; GENE OVEREXPRESSION; GENETIC VARIABILITY; GLIOBLASTOMA; GLYCOLYSIS; HUMAN; HUMAN TISSUE; NITROBLUE TETRAZOLIUM TEST; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STABLE EXPRESSION; TRANSIENT EXPRESSION; TUMOR CELL;

ASTROCYTOMA; BRAIN; BRAIN NEOPLASMS; CELL COUNT; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; DOWN-REGULATION; GLIOBLASTOMA; HUMANS; NEOPLASM STAGING; PHOSPHOFRUCTOKINASE-2; POLYMERASE CHAIN REACTION; PROTEIN ISOFORMS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TIME FACTORS; TRANSFECTION;

EID: 70449707222     PISSN: 03051846     EISSN: 13652990     Source Type: Journal    
DOI: 10.1111/j.1365-2990.2009.01027.x     Document Type: Article

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