Identification of a novel nuclear localization signal and speckle-targeting sequence of tuftelin-interacting protein 11, a splicing factor involved in spliceosome disassembly

Biochemical and Biophysical Research Communications

Volumn 390, Issue 3, 2009, Pages 1044-1050

  Tannukit, Sissada ^a   Crabb, Tara L ^b   Hertel, Klemens J ^b   Wen, Xin ^a   Jans, David A ^c   Paine, Michael L ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c MONASH UNIVERSITY   (Australia)

Author keywords

G patch; Lariat intron; Nuclear localization signal; RNA processing

Indexed keywords

AMINO ACID; NUCLEAR PROTEIN; SMALL INTERFERING RNA; SPECKLE TARGETING SEQUENCE PROTEIN; TUFTELIN INTERACTING PROTEIN 11; UNCLASSIFIED DRUG;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL SURVIVAL; CONTROLLED STUDY; HUMAN; HUMAN TISSUE; INTRON; NUCLEAR LOCALIZATION SIGNAL; OPEN READING FRAME; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN ASSEMBLY; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; RNA PROCESSING; RNA SPLICING; SEQUENCE ANALYSIS; SPECKLE TARGETING SEQUENCE; SPLICEOSOME; TRANSIENT TRANSFECTION;

AMINO ACID SEQUENCE; ANIMALS; CELL LINE; CELL NUCLEUS; HUMANS; MICE; MOLECULAR SEQUENCE DATA; NUCLEAR LOCALIZATION SIGNALS; NUCLEAR PROTEINS; PROTEIN STRUCTURE, TERTIARY; RNA SPLICING; SPLICEOSOMES; VESICULAR TRANSPORT PROTEINS;

EID: 70449707101     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2009.10.111     Document Type: Article

References (26)

1. Zhou Z., Licklider L.J., Gygi S.P., and Reed R. Comprehensive proteomic analysis of the human spliceosome. Nature 419 (2002) 182-185
2. Jurica M.S., and Moore M.J. Pre-mRNA splicing: awash in a sea of proteins. Mol. Cell 12 (2003) 5-14
3. Wen X., Lei Y.P., Zhou Y.L., Okamoto C.T., Snead M.L., and Paine M.L. Structural organization and cellular localization of tuftelin-interacting protein 11 (TFIP11). Cell. Mol. Life Sci. 62 (2005) 1038-1046
4. Ji Q., Huang C.H., Peng J., Hashmi S., Ye T., and Chen Y. Characterization of STIP, a multi-domain nuclear protein, highly conserved in metazoans, and essential for embryogenesis in Caenorhabditis elegans. Exp. Cell Res. 313 (2007) 1460-1472
5. Stanek D., Pridalova-Hnilicova J., Novotny I., Huranova M., Blazikova M., Wen X., Sapra A.K., and Neugebauer K.M. Spliceosomal small nuclear ribonucleoprotein particles repeatedly cycle through Cajal bodies. Mol. Biol. Cell 19 (2008) 2534-2543
6. Morris G.E. The Cajal body. Biochim. Biophys. Acta 1783 (2008) 2108-2115
7. Boon K.L., Auchynnikava T., Edwalds-Gilbert G., Barrass J.D., Droop A.P., Dez C., and Beggs J.D. Yeast ntr1/spp382 mediates prp43 function in postspliceosomes. Mol. Cell Biol. 26 (2006) 6016-6023
8. Tsai R.T., Fu R.H., Yeh F.L., Tseng C.K., Lin Y.C., Huang Y.H., and Cheng S.C. Spliceosome disassembly catalyzed by Prp43 and its associated components Ntr1 and Ntr2. Genes Dev. 19 (2005) 2991-3003
9. Tsai R.T., Tseng C.K., Lee P.J., Chen H.C., Fu R.H., Chang K.J., Yeh F.L., and Cheng S.C. Dynamic interactions of Ntr1-Ntr2 with Prp43 and with U5 govern the recruitment of Prp43 to mediate spliceosome disassembly. Mol. Cell Biol. 27 (2007) 8027-8037
10. Pandit S., Lynn B., and Rymond B.C. Inhibition of a spliceosome turnover pathway suppresses splicing defects. Proc. Natl. Acad. Sci. USA 103 (2006) 13700-13705
11. Tanaka N., Aronova A., and Schwer B. Ntr1 activates the Prp43 helicase to trigger release of lariat-intron from the spliceosome. Genes Dev. 21 (2007) 2312-2325
12. Wen X., Tannukit S., and Paine M.L. TFIP11 interacts with mDEAH9, an RNA helicase involved in spliceosome disassembly. Int. J. Mol. Sci. 9 (2008) 2105-2113
13. Yoshimoto R., Kataoka N., Okawa K., and Ohno M. Isolation and characterization of post-splicing lariat-intron complexes. Nucleic Acids Res. (2009) 891-902
14. Deckert J., Hartmuth K., Boehringer D., Behzadnia N., Will C.L., Kastner B., Stark H., Urlaub H., and Luhrmann R. Protein composition and electron microscopy structure of affinity-purified human spliceosomal B complexes isolated under physiological conditions. Mol. Cell Biol. 26 (2006) 5528-5543
15. Silverman E.J., Maeda A., Wei J., Smith P., Beggs J.D., and Lin R.J. Interaction between a G-patch protein and a spliceosomal DEXD/H-box ATPase that is critical for splicing. Mol. Cell Biol. 24 (2004) 10101-10110
16. Tannukit S., Wen X., Wang H., and Paine M.L. TFIP11, CCNL1 and EWSR1 protein-protein interactions, and their nuclear localization. Int. J. Mol. Sci. 9 (2008) 1504-1514
17. Madin K., Sawasaki T., Ogasawara T., and Endo Y. A highly efficient and robust cell-free protein synthesis system prepared from wheat embryos: plants apparently contain a suicide system directed at ribosomes. Proc. Natl. Acad. Sci. USA 97 (2000) 559-564
18. Hicks M.J., Lam B.J., and Hertel K.J. Analyzing mechanisms of alternative pre-mRNA splicing using in vitro splicing assays. Methods 37 (2005) 306-313
19. Nasim M.T., and Eperon I.C. A double-reporter splicing assay for determining splicing efficiency in mammalian cells. Nat. Protoc. 1 (2006) 1022-1028
20. Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E., Elledge S.J., and Gygi S.P. A quantitative atlas of mitotic phosphorylation. Proc. Natl. Acad. Sci. USA 105 (2008) 10762-10767
21. Ballif B.A., Villen J., Beausoleil S.A., Schwartz D., and Gygi S.P. Phosphoproteomic analysis of the developing mouse brain. Mol. Cell. Proteomics 3 (2004) 1093-1101
22. Villen J., Beausoleil S.A., Gerber S.A., and Gygi S.P. Large-scale phosphorylation analysis of mouse liver. Proc. Natl. Acad. Sci. USA 104 (2007) 1488-1493
23. Beausoleil S.A., Jedrychowski M., Schwartz D., Elias J.E., Villen J., Li J., Cohn M.A., Cantley L.C., and Gygi S.P. Large-scale characterization of HeLa cell nuclear phosphoproteins. Proc. Natl. Acad. Sci. USA 101 (2004) 12130-12135
24. Yeakley J.M., Tronchere H., Olesen J., Dyck J.A., Wang H.Y., and Fu X.D. Phosphorylation regulates in vivo interaction and molecular targeting of serine/arginine-rich pre-mRNA splicing factors. J. Cell Biol. 145 (1999) 447-455
25. Pettigrew C.A., and Brown M.A. Pre-mRNA splicing aberrations and cancer. Front. Biosci. 13 (2008) 1090-1105
26. Xing Y. Genomic analysis of RNA alternative splicing in cancers. Front. Biosci. 12 (2007) 4034-4041