-
1
-
-
0036463681
-
Metabonomics: A platform for studying drug toxicity and gene function
-
DOI 10.1038/nrd728
-
Nicholson JK, Connelly J, Lindon JC, Holmes E. Metabonomics: A platform for studying drug toxicity and gene function. Nat Rev Drug Discov 2002; 1(2): 153-161 (Pubitemid 41646523)
-
(2002)
Nature Reviews Drug Discovery
, vol.1
, Issue.2
, pp. 153-161
-
-
Nicholson, J.K.1
Connelly, J.2
Lindon, J.C.3
Holmes, E.4
-
2
-
-
19144371287
-
NMR-based metabonomic approaches for evaluating physiological influences on biofluid composition
-
DOI 10.1002/nbm.935
-
Bollard ME, Stanley EG, Lindon JC, Nicholson JK, Holmes E. NMR-based metabonomic approaches for evaluating physiological influences on biofluid composition. NMR Biomed 2005; 18(3): 143-162 (Pubitemid 40716122)
-
(2005)
NMR in Biomedicine
, vol.18
, Issue.3
, pp. 143-162
-
-
Bollard, M.E.1
Stanley, E.G.2
Lindon, J.C.3
Nicholson, J.K.4
Holmes, E.5
-
3
-
-
60249102576
-
Challenges and developments in tandem mass spectrometry based clinical metabolomics
-
Ceglarek U, Leichtle A, Brügel M, et al. Challenges and developments in tandem mass spectrometry based clinical metabolomics. Mol Cell Endocrinol 2009; 301(1-2): 266-271
-
(2009)
Mol Cell Endocrinol
, vol.301
, Issue.1-2
, pp. 266-271
-
-
Ceglarek, U.1
Leichtle, A.2
Brügel, M.3
-
5
-
-
38949209075
-
NMR-based metabolic profiling and metabonomic approaches to problems in molecular toxicology
-
DOI 10.1021/tx700335d
-
Coen M, Holmes E, Lindon JC, Nicholson JK. NMR-based metabolic profiling and metabonomic approaches to problems in molecular toxicology. Chem Res Toxicol 2008; 21(1): 9-27. (Pubitemid 351219705)
-
(2008)
Chemical Research in Toxicology
, vol.21
, Issue.1
, pp. 9-27
-
-
Coen, M.1
Holmes, E.2
Lindon, J.C.3
Nicholson, J.K.4
-
8
-
-
33745700438
-
Targeted profiling: Quantitative analysis of 1H NMR metabolomics data
-
Weljie AM, Newton J, Mercier P, Carlson E, Slupsky CM. Targeted profiling: Quantitative analysis of 1H NMR metabolomics data. Anal Chem 2006; 78(13): 4430-4442
-
(2006)
Anal Chem
, vol.78
, Issue.13
, pp. 4430-4442
-
-
Weljie, A.M.1
Newton, J.2
Mercier, P.3
Carlson, E.4
Slupsky, C.M.5
-
9
-
-
33745906535
-
Metabolomic analysis using optimized NMR and statistical methods
-
DOI 10.1016/j.ab.2006.04.014, PII S000326970600279X
-
Araníbar N, Ott K-H, Roongta V, Mueller L. Metabolomic analysis using optimized NMR and statistical methods. Anal Biochem 2006; 355(1): 62-70. (Pubitemid 44041397)
-
(2006)
Analytical Biochemistry
, vol.355
, Issue.1
, pp. 62-70
-
-
Aranibar, N.1
Ott, K.-H.2
Roongta, V.3
Mueller, L.4
-
10
-
-
44949182655
-
Improved residual water suppression: WET180
-
Mo H, Raftery D. Improved residual water suppression: WET180. J Biomol NMR 2008; 41(2): 105-111
-
(2008)
J Biomol NMR
, vol.41
, Issue.2
, pp. 105-111
-
-
Mo, H.1
Raftery, D.2
-
11
-
-
36849033384
-
Pre-SAT180, a simple and effective method for residual water suppression
-
DOI 10.1016/j.jmr.2007.09.016, PII S1090780707002832
-
Mo H, Raftery D. Pre-SAT180, a simple and effective method for residual water suppression. J Magn Reson 2008; 190(1): 1-6. (Pubitemid 350235244)
-
(2008)
Journal of Magnetic Resonance
, vol.190
, Issue.1
, pp. 1-6
-
-
Mo, H.1
Raftery, D.2
-
13
-
-
23444432495
-
Progress toward automated metabolic profiling of human serum: Comparison of CPMG and gradient-filtered NMR analytical methods
-
DOI 10.1016/j.jpba.2004.09.060, PII S0731708505001287
-
Lucas LH, Larive CK, Wilkinson PS, Huhn S. Progress toward automated metabolic profiling of human serum: Comparison of CPMG and gradient-filtered NMR analytical methods. J Pharm Biomed Anal 2005; 39(1-2): 156-163 (Pubitemid 41112132)
-
(2005)
Journal of Pharmaceutical and Biomedical Analysis
, vol.39
, Issue.1-2
, pp. 156-163
-
-
Lucas, L.H.1
Larive, C.K.2
Wilkinson, P.S.3
Huhn, S.4
-
14
-
-
34250901859
-
Robust deconvolution of complex mixtures by covariance TOCSY spectroscopy
-
DOI 10.1002/anie.200604599
-
Zhang F, Brüschweiler R. Robust deconvolution of complex mixtures by covariance TOCSY spectroscopy. Angew Chem 2007; 119(15): 2693-2696 (Pubitemid 46973551)
-
(2007)
Angewandte Chemie - International Edition
, vol.46
, Issue.15
, pp. 2639-2642
-
-
Zhang, F.1
Bruschweiler, R.2
-
15
-
-
38949178155
-
Metabolite identification via the Madison Metabolomics Consortium Database [3]
-
DOI 10.1038/nbt0208-162, PII NBT0208162
-
Cui Q, Lewis IA, Hegeman AD, et al. Metabolite identification via the Madison Metabolomics Consortium Database. Nat Biotech 2008; 26(2): 162-164 (Pubitemid 351225941)
-
(2008)
Nature Biotechnology
, vol.26
, Issue.2
, pp. 162-164
-
-
Cui, Q.1
Lewis, I.A.2
Hegeman, A.D.3
Anderson, M.E.4
Li, J.5
Schulte, C.F.6
Westler, W.M.7
Eghbalnia, H.R.8
Sussman, M.R.9
Markley, J.L.10
-
16
-
-
33846088138
-
HMDB: The Human Metabolome Database
-
Wishart DS, Tzur D, Knox C, et al. HMDB: The Human Metabolome Database. Nucleic Acids Res 2007; 35(suppl-1): D521-26.
-
(2007)
Nucleic Acids Res
, vol.35
, Issue.SUPPL.-1
-
-
Wishart, D.S.1
Tzur, D.2
Knox, C.3
-
18
-
-
33847358695
-
Analytical strategies in metabonomics
-
Lenz EM, Wilson ID. Analytical strategies in metabonomics. J Proteome Res 2006; 6(2): 443-458
-
(2006)
J Proteome Res
, vol.6
, Issue.2
, pp. 443-458
-
-
Lenz, E.M.1
Wilson, I.D.2
-
19
-
-
50849141305
-
A multi-metabolite analysis of serum by 1H NMR spectroscopy: Early systemic signs of Alzheimer's disease
-
Tukiainen T, Tynkkynen T, Mäkinen VP, et al. A multi-metabolite analysis of serum by 1H NMR spectroscopy: Early systemic signs of Alzheimer's disease. Biochem Biophys Res Commun 2008; 375(3): 356-361
-
(2008)
Biochem Biophys Res Commun
, vol.375
, Issue.3
, pp. 356-361
-
-
Tukiainen, T.1
Tynkkynen, T.2
Mäkinen, V.P.3
-
20
-
-
58349109682
-
Metabolomic biomarkers in a model of asthma exacerbation: Urine nuclear magnetic resonance
-
Saude EJ, Obiefuna IP, Somorjai RL, et al. Metabolomic biomarkers in a model of asthma exacerbation: urine nuclear magnetic resonance. Am J Respir Crit Care Med 2009; 179(1): 25-34.
-
(2009)
Am J Respir Crit Care Med
, vol.179
, Issue.1
, pp. 25-34
-
-
Saude, E.J.1
Obiefuna, I.P.2
Somorjai, R.L.3
-
21
-
-
48949100761
-
A 1H nuclearmagnetic resonance-based metabonomic approach for grading hepatic encephalopathy and monitoring the e¡ects of therapeutic hypothermia in rats
-
Barba I, Chatauret N, García-Dorado D, Córdoba J. A 1H nuclearmagnetic resonance-based metabonomic approach for grading hepatic encephalopathy and monitoring the e¡ects of therapeutic hypothermia in rats. Liver Int 2008; 28(8): 1141-1148
-
(2008)
Liver Int
, vol.28
, Issue.8
, pp. 1141-1148
-
-
Barba, I.1
Chatauret, N.2
García-Dorado, D.3
Córdoba, J.4
-
22
-
-
26244457653
-
Proteomic and metabolomic analyses of atherosclerotic vessels from apolipoprotein E-deficient mice reveal alterations in inflammation, oxidative stress, and energy metabolism
-
DOI 10.1161/01.ATV.0000183928.25844.f6
-
Mayr M, Chung Y-L, Mayr U, et al. Proteomic and metabolomic analyses of atherosclerotic vessels from apolipoprotein E-deficient mice reveal alterations in inflammation, oxidative stress, and energy metabolism. Arterioscler Thromb Vasc Biol 2005; 25(10): 2135-2142 (Pubitemid 41416312)
-
(2005)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.25
, Issue.10
, pp. 2135-2142
-
-
Mayr, M.1
Chung, Y.-L.2
Mayr, U.3
Yin, X.4
Ly, L.5
Troy, H.6
Fredericks, S.7
Hu, Y.8
Griffiths, J.R.9
Xu, Q.10
-
23
-
-
60349122819
-
Characterization of 1H NMR detectable mobile lipids in cells from human adenocarcinomas
-
Luciani AM, Grande S, Palma A, et al. Characterization of 1H NMR detectable mobile lipids in cells from human adenocarcinomas. FEBS J 2009; 276(5): 1333-1346
-
(2009)
FEBS J
, vol.276
, Issue.5
, pp. 1333-1346
-
-
Luciani, A.M.1
Grande, S.2
Palma, A.3
-
24
-
-
0027405652
-
An investigation of the abnormal metabolic status of synovial fluid from patients with rheumatoid arthritis by high field proton nuclear magnetic resonance spectroscopy
-
DOI 10.1016/0014-5793(93)81508-W
-
Naughton D, Whelan M, Smith EC, et al. An investigation of the abnormal metabolic status of synovial fluid from patients with rheumatoid arthritis by high field proton nuclear magnetic resonance spectroscopy. FEBS Lett 1993; 317(1,2): 135-138 (Pubitemid 23043956)
-
(1993)
FEBS Letters
, vol.317
, Issue.1-2
, pp. 135-138
-
-
Naughton, D.1
Whelan, M.2
Smith, E.C.3
Williams, R.4
Blake, D.R.5
Grootveld, M.6
-
25
-
-
34948910696
-
1H NMR spectroscopy
-
DOI 10.1021/pr070123j
-
Weljie AM, Dowlatabadi R, Miller BJ, Vogel HJ, Jirik FR. An inflammatory arthritis-associated metabolite biomarker pattern revealed by 1H NMR spectroscopy. J Proteome Res 2007; 6(9): 3456-3464 (Pubitemid 47522736)
-
(2007)
Journal of Proteome Research
, vol.6
, Issue.9
, pp. 3456-3464
-
-
Weljie, A.M.1
Dowlatabadi, R.2
Miller, B.J.3
Vogel, H.J.4
Jirik, F.R.5
-
26
-
-
52049118795
-
Correlative and quantitative 1H NMR-based metabolomics reveals specific metabolic pathway disturbances in diabetic rats
-
Zhang S, Nagana Gowda GA, Asiago V, et al. Correlative and quantitative 1H NMR-based metabolomics reveals specific metabolic pathway disturbances in diabetic rats. Anal Biochem 2008; 383(1): 76-84.
-
(2008)
Anal Biochem
, vol.383
, Issue.1
, pp. 76-84
-
-
Zhang, S.1
Nagana Gowda, G.A.2
Asiago, V.3
-
27
-
-
33847378014
-
Rapid and noninvasive metabonomic characterization of inflammatory bowel disease
-
DOI 10.1021/pr060470d
-
Marchesi JR, Holmes E, Khan F, et al. Rapid and noninvasive metabonomic characterization of inflammatory bowel disease. J Proteome Res 2007; 6(2): 546-551 (Pubitemid 46340158)
-
(2007)
Journal of Proteome Research
, vol.6
, Issue.2
, pp. 546-551
-
-
Marchesi, J.R.1
Holmes, E.2
Khan, F.3
Kochhar, S.4
Scanlan, P.5
Shanahan, F.6
Wilson, I.D.7
Wang, Y.8
-
28
-
-
57049170939
-
Metabolism of the colonic mucosa in patients with inflammatory bowel diseases: An in vitro proton magnetic resonance spectroscopy study
-
Balasubramanian K, Kumar S, Singh RR, et al. Metabolism of the colonic mucosa in patients with inflammatory bowel diseases: An in vitro proton magnetic resonance spectroscopy study. Magn Reson Imaging 2009; 27(1): 79-86.
-
(2009)
Magn Reson Imaging
, vol.27
, Issue.1
, pp. 79-86
-
-
Balasubramanian, K.1
Kumar, S.2
Singh, R.R.3
-
29
-
-
0027521572
-
Interleukin-10-deficient mice develop chronic enterocolitis
-
DOI 10.1016/0092-8674(93)80068-P
-
Kühn R, Löhler J, Rennick D, Rajewsky K, Müller W. Interleukin- 10-deficient mice develop chronic enterocolitis. Cell 1993; 75(2): 263-274 (Pubitemid 23320290)
-
(1993)
Cell
, vol.75
, Issue.2
, pp. 263-274
-
-
Kuhn, R.1
Lohler, J.2
Rennick, D.3
Rajewsky, K.4
Muller, W.5
-
30
-
-
66749130197
-
Metabolic assessment of gradual development of moderate experimental colitis in IL-10 deficient mice
-
Martin F-PJ, Rezzi S, Montoliu I, et al. Metabolic assessment of gradual development of moderate experimental colitis in IL-10 deficient mice. J Proteome Res 2009; 8(5): 2376-2387
-
(2009)
J Proteome Res
, vol.8
, Issue.5
, pp. 2376-2387
-
-
Martin, F.-P.J.1
Rezzi, S.2
Montoliu, I.3
-
31
-
-
49049113111
-
Urinary metabolic profiles of inflammatory bowel disease in Interleukin-10 gene-deficient mice
-
Murdoch TB, Fu H, MacFarlane S, et al. Urinary metabolic profiles of inflammatory bowel disease in Interleukin-10 gene-deficient mice. Anal Chem 2008; 80(14): 5524-5531
-
(2008)
Anal Chem
, vol.80
, Issue.14
, pp. 5524-5531
-
-
Murdoch, T.B.1
Fu, H.2
MacFarlane, S.3
-
32
-
-
65249184431
-
Nontargeted urinary metabolite profiling of a mouse model of Crohn's disease
-
Lin HM, Edmunds SJ, Helsby NA, Ferguson LR, Rowan DD. Nontargeted urinary metabolite profiling of a mouse model of Crohn's disease. J Proteome Res 2009; 8(4): 2045-2057
-
(2009)
J Proteome Res
, vol.8
, Issue.4
, pp. 2045-2057
-
-
Lin, H.M.1
Edmunds, S.J.2
Helsby, N.A.3
Ferguson, L.R.4
Rowan, D.D.5
-
33
-
-
0038215374
-
Tolerance, DCs and tryptophan: Much ado about IDO
-
Grohmann U, Fallarino F, Puccetti P. Tolerance, DCs and tryptophan: Much ado about IDO. Trends Immunol 2003; 24(5): 242-248
-
(2003)
Trends Immunol
, vol.24
, Issue.5
, pp. 242-248
-
-
Grohmann, U.1
Fallarino, F.2
Puccetti, P.3
-
34
-
-
0037491081
-
L-glycine: A novel antiinflammatory, immunomodulatory, and cytoprotective agent
-
DOI 10.1097/00075197-200303000-00013
-
Zhong Z, Wheeler MD, Li X, et al. L-Glycine: A novel antiinflammatory, immunomodulatory, and cytoprotective agent. Curr Opin Clin Nutr Metab Care 2003; 6(2): 229-240 (Pubitemid 40674528)
-
(2003)
Current Opinion in Clinical Nutrition and Metabolic Care
, vol.6
, Issue.2
, pp. 229-240
-
-
Zhong, Z.1
Wheeler, M.D.2
Li, X.3
Froh, M.4
Schemmer, P.5
Yin, M.6
Bunzendaul, H.7
Bradford, B.8
Lemasters, J.J.9
-
35
-
-
0034871510
-
Dietary glycine prevents peptidoglycan polysaccharide-induced reactive arthritis in the rat: Role for glycine-gated chloride channel
-
DOI 10.1128/IAI.69.9.5883-5891.2001
-
Li X, Bradford BU, Wheeler MD, et al. Dietary glycine prevents peptidoglycan polysaccharide-induced reactive arthritis in the rat: Role for glycine-gated chloride channel. Infect Immun 2001; 69(9): 5883-5891 (Pubitemid 32786529)
-
(2001)
Infection and Immunity
, vol.69
, Issue.9
, pp. 5883-5891
-
-
Li, X.1
Bradford, B.U.2
Wheeler, M.D.3
Stimpson, S.A.4
Pink, H.M.5
Brodie, T.A.6
Schwab, J.H.7
Thurman, R.G.8
-
36
-
-
55249102198
-
NMR-based metabonomic investigations into the metabolic profile of the senescence-accelerated mouse
-
Jiang N, Yan X, Zhou W, et al. NMR-based metabonomic investigations into the metabolic profile of the senescence-accelerated mouse. J Proteome Res 2008; 7(9): 3678-3686
-
(2008)
J Proteome Res
, vol.7
, Issue.9
, pp. 3678-3686
-
-
Jiang, N.1
Yan, X.2
Zhou, W.3
-
37
-
-
66749107425
-
Halofuginone inhibits TH17 cell differentiation by activating the amino acid starvation response
-
Sundrud MS, Koralov SB, Feuerer M, et al. Halofuginone inhibits TH17 cell differentiation by activating the amino acid starvation response. Science 2009; 324(5932): 1334-1338
-
(2009)
Science
, vol.324
, Issue.5932
, pp. 1334-1338
-
-
Sundrud, M.S.1
Koralov, S.B.2
Feuerer, M.3
-
38
-
-
20044367655
-
Antimalarial activities and therapeutic properties of febrifugine analogs
-
DOI 10.1128/AAC.49.3.1169-1176.2005
-
Jiang S, Zeng Q, Gettayacamin M, et al. Antimalarial activities and therapeutic properties of febrifugine analogs. Antimicrob Agents Chemother 2005; 49(3): 1169-1176 (Pubitemid 40327741)
-
(2005)
Antimicrobial Agents and Chemotherapy
, vol.49
, Issue.3
, pp. 1169-1176
-
-
Jiang, S.1
Zeng, Q.2
Gettayacamin, M.3
Tungtaeng, A.4
Wannaying, S.5
Lim, A.6
Hansukjariya, P.7
Okunji, C.O.8
Zhu, S.9
Fang, D.10
-
39
-
-
0032054482
-
Halofuginone: A novel antifibrotic therapy
-
Pines M, Nagler A. Halofuginone: A novel antifibrotic therapy. Gen Pharmacol 1998; 30(4): 445-450
-
(1998)
Gen Pharmacol
, vol.30
, Issue.4
, pp. 445-450
-
-
Pines, M.1
Nagler, A.2
-
40
-
-
27544490377
-
Interleukin 17- producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages
-
Harrington LE, Hatton RD, Mangan PR, et al. Interleukin 17- producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages. Nat Immunol 2005; 6(11): 1123-1132
-
(2005)
Nat Immunol
, vol.6
, Issue.11
, pp. 1123-1132
-
-
Harrington, L.E.1
Hatton, R.D.2
Mangan, P.R.3
-
41
-
-
33846966636
-
A brief history of TH17, the first major revision in the TH1/TH2 hypothesis of T cell-mediated tissue damage
-
Steinman L. A brief history of TH17, the first major revision in the TH1/TH2 hypothesis of T cell-mediated tissue damage. Nat Med 2007; 13(2): 139-145
-
(2007)
Nat Med
, vol.13
, Issue.2
, pp. 139-145
-
-
Steinman, L.1
-
42
-
-
34247555353
-
Differentiation and function of Th17 T cells
-
Stockinger B, Veldhoen M. Differentiation and function of Th17 T cells. Curr Opin Immunol 2007; 19(3): 281-286
-
(2007)
Curr Opin Immunol
, vol.19
, Issue.3
, pp. 281-286
-
-
Stockinger, B.1
Veldhoen, M.2
|