Incorporation of ionic ligands accelerates drug release from LDI-glycerol polyurethanes

Acta Biomaterialia

Volumn 6, Issue 1, 2010, Pages 144-153

  Sivak, Wesley N ^a,b   Zhang, Jianying ^a   Petoud, Stephane ^c   Beckman, Eric J ^a  

^a University of Pittsburgh   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF PITTSBURGH   (United States)

Author keywords

Camptothecin; Choline chloride; Drug delivery; Isethionic acid; Polyurethane

Indexed keywords

AMINO ACIDS; BODY FLUIDS; CHLORINE COMPOUNDS; CONTROLLED DRUG DELIVERY; FLUORESCENCE; FLUORESCENCE MICROSCOPY; GLYCEROL; LIGANDS; ORGANOMETALLICS; SCANNING ELECTRON MICROSCOPY; SWELLING; TARGETED DRUG DELIVERY;

BIODEGRADABLE POLYURETHANES; CAMPTOTHECINS; CHOLINE CHLORIDE; DRUG RELEASE; IONIC LIGANDS; IONIC MATERIALS; ISETHIONIC ACID; LYSINE DIISOCYANATE; POLYURETHANE MATERIALS; SYNTHESISED;

POLYURETHANES;

7 TERT BUTYLDIMETHYLSILYL 10 HYDROXYCAMPTOTHECIN; ANTINEOPLASTIC AGENT; BUTANOL; CAMPTOTHECIN DERIVATIVE; CHOLINE; CYANIC ACID DERIVATIVE; DB 67; FUNCTIONAL GROUP; GLYCEROL; ISETHIONIC ACID; ISOCYANATE; LIGAND; LYSINE DIISOCYANATE; ORGANOMETALLIC COMPOUND; POLYURETHAN; TERTIARY AMINE; UNCLASSIFIED DRUG;

ARTICLE; BIODEGRADABILITY; CATALYST; CHEMICAL STRUCTURE; CONTROLLED RELEASE FORMULATION; COVALENT BOND; DRUG DELIVERY SYSTEM; DRUG DESIGN; DRUG STRUCTURE; PRIORITY JOURNAL; SYNTHESIS;

EID: 70449699715     PISSN: 17427061     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.actbio.2009.06.013     Document Type: Article

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