DNA methyltransferase inhibitors increase baculovirus-mediated gene expression in mammalian cells when applied before infection

Analytical Biochemistry

Volumn 396, Issue 2, 2010, Pages 322-324

  Wang, Xin ^a   Yin, Juan ^a   Huang, Xiaoxia ^a   Zhong, Jiang ^a  

^a FUDAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLATION; CELL CULTURE; GENE TRANSFER; MAMMALS; VIRUSES;

BACULOVIRUS; DEACETYLATION; DNA METHYLTRANSFERASES; GENE DELIVERY VECTORS; GENE SILENCING; HOST CELLS; MAMMALIAN CELL LINES; MAMMALIAN CELLS;

GENE EXPRESSION;

5 AZA 2' DEOXYCYTIDINE; AZACITIDINE; DNA METHYLTRANSFERASE INHIBITOR; HISTONE; VIRUS VECTOR;

ANIMAL CELL; ARTICLE; BACULOVIRUS; CELL ASSAY; CELL CULTURE; CELL LINE; CELL STRAIN HEK293; CHO CELL; CONTROLLED STUDY; CYTOTOXICITY; DEACETYLATION; ENZYME INHIBITION; EPIGENETICS; FEMALE; GENE EXPRESSION; GENE SILENCING; HOST CELL; HUMAN; HUMAN CELL; INOCULATION; MAMMAL CELL; NONHUMAN; PRIORITY JOURNAL; VIRAL GENE DELIVERY SYSTEM;

MAMMALIA;

EID: 70449699622     PISSN: 00032697     EISSN: 10960309     Source Type: Journal    
DOI: 10.1016/j.ab.2009.09.033     Document Type: Article

References (11)

1. Hu Y.-C. Baculoviral vector for gene delivery: a review. Curr. Gene Ther. 8 (2008) 54-65
2. Kitajima M., Hamazaki H., Miyano-Kurosaki N., and Takaku H. Characterization of baculovirus Autographa californica multiple nuclear polyhedrosis virus infection in mammalian cells. Biochem. Biophys. Res. Commun. 343 (2006) 378-384
3. Condreay J.P., Witherspoon S.M., Clay W.C., and Kost T.A. Transient and stable gene expression in mammalian cells transduced with a recombinant baculovirus vector. Proc. Natl. Acad. Sci. USA 96 (1999) 127-132
4. Luz-Madrigal A., Clapp C., Aranda J., and Vaca L. In vivo transcription targeting into the retinal vasculature using recombination baculovirus carrying the human flt-1 promoter. Virol. J. 4 (2007) 88
5. Stresemann C., and Lyko F. Modes of action of the DNA methyltransferase inhibitors azacytidine and decitabine. Int. J. Cancer 123 (2008) 8-13
6. Wang X., Li L., Ding S., Huang X., Zhang J., Yin J., and Zhong J. Chicken HS4 insulator significantly improves baculovirus-mediated foreign gene expression in insect cells by modifying the structure of neighbouring chromatin in virus minichromosome. J. Biotechnol. 142 (2009) 193-199
7. Wang L., Shan L., Yin J., Zhao M.L., Su D.M., and Zhong J. The activation of lytic replication of Epstein-Barr virus by baculovirus-mediated gene transduction. Arch. Virol. 151 (2006) 2047-2053
8. Lyko F., and Brown R. DNA methyltransferase inhibitors and the development of epigenetic cancer therapies. J. Natl. Cancer Inst. 97 (2005) 1498-1506
9. Chen W.Y., Bailey E.C., McCune S.L., Dong J.-Y., and Townes T.M. Reactivation of silenced, virally transduced gene by inhibitors of histone deacetylase. Proc. Natl. Acad. Sci. USA 94 (1997) 5798-5803
10. Ghoshal K., Datta J., Majumder S., Bai S., Kutay H., Motiwala T., and Jacob S.T. 5-AZA-deoxycytidine induces selective degradation of DNA methyltransferase 1 by proteasomal pathway that required the KEN box, bromo-adjacent homology domain, and nuclear localization signal. Mol. Cell. Biol. 25 (2005) 4727-4741
11. Lee H.P., Matsuura Y., Chen H.C., Chen Y.L., Chuang C.K., Abe T., Hwang S.M., Shiah H.C., and Hu Y.C. Baculovirus transduction of chondrocytes elicits interferon-α/β and suppresses transgene expression. J. Gene Med. 11 (2009) 302-312