Tissue-specific PAI-1 gene expression and glycosylation pattern in insulin-resistant old rats

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 297, Issue 5, 2009, Pages

  Serrano, R ^a   Barrenetxe, J ^a   Orbe, J ^a   Rodriguez J A ^a   Gallardo, N ^b   Martinez C ^b   Andres A ^b   Paramo J A ^a  

^a UNIVERSITY OF NAVARRA   (Spain)

^b UNIVERSITY OF CASTILLA LA MANCHA   (Spain)

Author keywords

Aging; Cardiovascular disease; Insulin resistance

Indexed keywords

MESSENGER RNA; PLASMINOGEN ACTIVATOR INHIBITOR 1;

ADIPOCYTE; AFFINITY CHROMATOGRAPHY; AGED; AGING; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARDIOVASCULAR DISEASE; CARDIOVASCULAR RISK; ENDOTHELIUM CELL; GENE EXPRESSION; INSULIN RESISTANCE; INTRAABDOMINAL FAT; MALE; NONHUMAN; PRIORITY JOURNAL; PROADIPOCYTE; PROTEIN BLOOD LEVEL; PROTEIN GLYCOSYLATION; PROTEIN PURIFICATION; RAT; SUPERNATANT; TISSUE SPECIFICITY; WHITE ADIPOSE TISSUE;

ADIPOCYTES; ADIPOSE TISSUE, WHITE; AGING; ANIMALS; CELL DIFFERENTIATION; DISEASE MODELS, ANIMAL; GENE EXPRESSION REGULATION; GLYCOSYLATION; INSULIN RESISTANCE; LIVER; MALE; PLASMINOGEN ACTIVATOR INHIBITOR 1; RATS; RATS, WISTAR; RNA, MESSENGER;

EID: 70449686366     PISSN: 03636119     EISSN: 15221490     Source Type: Journal    
DOI: 10.1152/ajpregu.00093.2009     Document Type: Article

References (33)

1. Alessi MC, Bastelica D, Mavri A, Morange P, Berthet B, Grino M, Juhan-Vague I. Plasma PAI-1 levels are more strongly related to liver steatosis than to adipose tissue accumulation. Arterioscler Thromb Vasc Biol 23: 1262-1268, 2003. (Pubitemid 36873814)
2. Alessi MC, Declerck PJ, De Mol M, Nelles L, Collen D. Purification and characterization of natural and recombinant human plasminogen activator inhibitor-1 (PAI-1). Eur J Biochem 175: 531-540, 1988. (Pubitemid 18202036)
3. Alessi MC, Juhan-Vague I. PAI-1 and the metabolic syndrome: links, causes, and consequences. Arterioscler Thromb Vasc Biol 26: 2200-2207, 2006. (Pubitemid 44465712)
4. Alessi MC, Peiretti F, Morange P, Henry M, Nalbone G, Juhan-Vague I. Production of plasminogen activator inhibitor 1 by human adipose tissue: possible link between visceral fat accumulation and vascular disease. Diabetes 46: 860-867, 1997. (Pubitemid 27188265)
5. Anand SS, Yi Q, Gerstein H, Lonn E, Jacobs R, Vuksan V, Teo K, Davis B, Montague P, Yusuf S. Relationship of metabolic syndrome and fibrinolytic dysfunction to cardiovascular disease. Circulation 108: 420-425, 2003. (Pubitemid 36935534)
6. Bastelica D, Morange P, Berthet B, Borghi H, Lacroix O, Grino M, Juhan-Vague I, Alessi MC. Stromal cells are the main plasminogen activator inhibitor-1-producing cells in human fat: evidence of differences between visceral and subcutaneous deposits. Arterioscler Thromb Vasc Biol 22: 173-178, 2002. (Pubitemid 34076250)
7. Brogren H, Sihlbom C, Wallmark K, Lonn M, Deinum J, Karlsson L, Jern S. Heterogeneous glycosylation patterns of human PAI-1 may reveal its cellular origin. Thromb Res 122: 271-281, 2008.
8. Chen Y, Billadello JJ, Schneider DJ. Identification and localization of a fatty acid response region in the human plasminogen activator inhibitor-1 gene. Arterioscler Thromb Vasc Biol 20: 2696-2701, 2000.
9. DeFronzo RA. Insulin resistance: a multifaceted syndrome responsible for NIDDM, obesity, hypertension, dyslipidaemia and atherosclerosis. Neth J Med 50: 191-197, 1997.
10. Escriva F, Agote M, Rubio E, Molero JC, Pascual-Leone AM, Andres A, Satrustegui J, Carrascosa JM. In vivo insulin-dependent glucose uptake of specific tissues is decreased during aging of mature Wistar rats. Endocrinology 138: 49-54, 1997. (Pubitemid 27009404)
11. Escriva F, Gavete ML, Fermin Y, Perez C, Gallardo N, Alvarez C, Andres A, Ros M, Carrascosa JM. Effect of age and moderate food restriction on insulin sensitivity in Wistar rats: role of adiposity. J Endocrinol 194: 131-141, 2007. (Pubitemid 47162893)
12. Festa A, D'Agostino R Jr, Mykkanen L, Tracy RP, Zaccaro DJ, Hales CN, Haffner SM. Relative contribution of insulin and its precursors to fibrinogen and PAI-1 in a large population with different states of glucose tolerance. The Insulin Resistance Atherosclerosis Study (IRAS). Arterioscler Thromb Vasc Biol 19: 562-568, 1999. (Pubitemid 29135156)
13. Gils A, Pedersen KE, Skottrup P, Christensen A, Naessens D, Deinum J, Enghild JJ, Declerck PJ, Andreasen PA. Biochemical importance of glycosylation of plasminogen activator inhibitor-1. Thromb Haemost 90: 206-217, 2003. (Pubitemid 37006281)
14. Hashimoto Y, Kobayashi A, Yamazaki N, Sugawara Y, Takada Y, Takada A. Relationship between age and plasma t-PA, PA-inhibitor, and PA activity. Thromb Res 46: 625-633, 1987. (Pubitemid 17085250)
15. Ingelsson E, Pencina MJ, Tofler GH, Benjamin EJ, Lanier KJ, Jacques PF, Fox CS, Meigs JB, Levy D, Larson MG, Selhub J, D'Agostino RB Sr, Wang TJ, Vasan RS. Multimarker approach to evaluate the incidence of the metabolic syndrome and longitudinal changes in metabolic risk factors: the Framingham Offspring Study. Circulation 116: 984-992, 2007. (Pubitemid 47329563)
16. Juhan-Vague I, Alessi MC, Vague P. Increased plasma plasminogen activator inhibitor 1 levels. A possible link between insulin resistance and atherothrombosis. Diabetologia 34: 457-462, 1991.
17. Lawrence D, Strandberg L, Grundstrom T, Ny T. Purification of active human plasminogen activator inhibitor 1 from Escherichia coli. Comparison with natural and recombinant forms purified from eucaryotic cells. Eur J Biochem 186: 523-533, 1989. (Pubitemid 20030102)
18. Mehta J, Mehta P, Lawson D, Saldeen T. Plasma tissue plasminogen activator inhibitor levels in coronary artery disease: correlation with age and serum triglyceride concentrations. J Am Coll Cardiol 9: 263-268, 1987. (Pubitemid 17013784)
19. Narimiya M, Azhar S, Dolkas CB, Mondon CE, Sims C, Wright DW, Reaven GM. Insulin resistance in older rats. Am J Physiol Endocrinol Metab 246: E397-E404, 1984.
20. Nishimura H, Kuzuya H, Okamoto M, Yoshimasa Y, Yamada K, Ida T, Kakehi T, Imura H. Change of insulin action with aging in conscious rats determined by euglycemic clamp. Am J Physiol Endocrinol Metab 254: E92-E98, 1988.
21. Pannacciulli N, De M, V, Marino R, Giorgino R, De Pergola G. Effect of glucose tolerance status on PAI-1 plasma levels in overweight and obese subjects. Obes Res 10: 717-725, 2002. (Pubitemid 135687511)
22. Paramo JA, Colucci M, Collen D, van de Werf F. Plasminogen activator inhibitor in the blood of patients with coronary artery disease. Br Med J (Clin Res Ed) 291: 573-574, 1985. (Pubitemid 15225460)
23. Rader DJ. Effect of insulin resistance, dyslipidemia, and intra-abdominal adiposity on the development of cardiovascular disease and diabetes mellitus. Am J Med 120: S12-S18, 2007. (Pubitemid 46298723)
24. Ruiz P, Pulido JA, Martinez C, Carrascosa JM, Satrustegui J, Andres A. Effect of aging on the kinetic characteristics of the insulin receptor autophosphorylation in rat adipocytes. Arch Biochem Biophys 296: 231-238, 1992.
25. Samad F, Yamamoto K, Loskutoff DJ. Distribution and regulation of plasminogen activator inhibitor-1 in murine adipose tissue in vivo. Induction by tumor necrosis factor- and lipopolysaccharide. J Clin Invest 97: 37-46, 1996. (Pubitemid 26021692)
26. Sawdey MS, Loskutoff DJ. Regulation of murine type 1 plasminogen activator inhibitor gene expression in vivo. Tissue specificity and induction by lipopolysaccharide, tumor necrosis factor-α, and transforming growth factor-β. J Clin Invest 88: 1346-1353, 1991.
27. Serrano R, Villar M, Martinez C, Carrascosa JM, Gallardo N, Andres A. Differential gene expression of insulin receptor isoforms A and B and insulin receptor substrates 1, 2 and 3 in rat tissues: modulation by aging and differentiation in rat adipose tissue. J Mol Endocrinol 34: 153-161, 2005. (Pubitemid 40305557)
28. Skurk T, Hauner H. Obesity and impaired fibrinolysis: role of adipose production of plasminogen activator inhibitor-1. Int J Obes Relat Metab Disord 28: 1357-1364, 2004. (Pubitemid 39481839)
29. Slawson C, Housley MP, Hart GW. O-GlcNAc cycling: how a single sugar post-translational modification is changing the way we think about signaling networks. J Cell Biochem 97: 71-83, 2006. (Pubitemid 43050180)
30. Verheijen JH, Chang GT, Kluft C. Evidence for the occurrence of a fast-acting inhibitor for tissue-type plasminogen activator in human plasma. Thromb Haemost 51: 392-395, 1984. (Pubitemid 14097900)
31. Wilding JP. The importance of free fatty acids in the development of Type 2 diabetes. Diabet Med 24: 934-945, 2007.
32. Wilkerson WR, Sane DC. Aging and thrombosis. Semin Thromb Hemost 28: 555-568, 2002.
33. Yamamoto K, Takeshita K, Shimokawa T, Yi H, Isobe K, Loskutoff DJ, Saito H. Plasminogen activator inhibitor-1 is a major stress-regulated gene: implications for stress-induced thrombosis in aged individuals. Proc Natl Acad Sci U S A 99: 890-895, 2002. (Pubitemid 34106606)