Drug discovery: Predicting promiscuity

Nature

Volumn 462, Issue 7270, 2009, Pages 167-168

  Hopkins, Andrew L ^a  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL COMPOUND; FLUOXETINE; PAROXETINE; PROTEIN;

BIOACTIVITY; DRUG DEVELOPMENT;

BIOLOGICAL ACTIVITY; CHEMICAL STRUCTURE; COMPUTER MODEL; CRYSTAL STRUCTURE; GENE; HUMAN GENOME; IN VITRO STUDY; IN VIVO STUDY; INTROSPECTION; PREDICTION; PRIORITY JOURNAL; PROTEIN MOTIF; SEXUALITY; SHORT SURVEY; VALIDATION STUDY; X RAY ANALYSIS;

ANIMALS; ARTIFICIAL INTELLIGENCE; COMPUTATIONAL BIOLOGY; DRUG DISCOVERY; HUMANS; LIGANDS; OFF-LABEL USE; PHARMACEUTICAL PREPARATIONS; REPRODUCIBILITY OF RESULTS; SUBSTRATE SPECIFICITY;

EID: 70449673534     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/462167a     Document Type: Short Survey

References (7)

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2. Keiser, M. J. et al. Nature 462, 175-181 (2009).
3. Nigsch, F., Bender, A., Jenkins, J. L. & Mitchell, J. B. J. Chem. Inf. Model. 48, 2313-2325 (2008).
4. Keiser, M. J. et al. Nature Biotechnol. 25, 197-206 (2007).
5. Yildirim, M. A. et al. Nature Biotechnol. 25, 1119-1126 (2007).
6. www.ebi.ac.uk/chembl
7. http://pubchem.ncbi.nlm.nih.gov