Obesity is not associated with mild asthma diagnosis in a population of spanish adults

Journal of Asthma

Volumn 46, Issue 9, 2009, Pages 867-871

  Barranco, Pilar ^a   Delgado, Julio ^b   Sastre, Joaquín ^c,d   Vega, José María ^e   Pascual, María José ^f   Barranco, Ruth ^c   García Río, Francisco ^a   Parra, Antonio ^g   Quirce, Santiago ^a,d  

^a HOSPITAL UNIVERSITARIO LA PAZ   (Spain)

^b HOSPITAL UNIVERSITARIO VIRGEN MACARENA   (Spain)

^c Hospital UniversitarioFundación Jiménez Díaz   (Spain)

^d INSTITUTO DE SALUD CARLOS III   (Spain)

^e HOSPITAL REGIONAL UNIVERSITARIO DE MÁLAGA   (Spain)

^f Allergy and Asthma Centre   (Spain)

^g Allergy Department   (Spain)

Author keywords

Airway hyperresponsiveness; Asthma; Atopy; Body mass index; Obesity

Indexed keywords

ALLERGEN; METHACHOLINE;

ADULT; ARTICLE; ASTHMA; ATOPY; BODY HEIGHT; BODY MASS; BODY WEIGHT; CLINICAL TRIAL; COMPARATIVE STUDY; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; DISEASE ASSOCIATION; FEMALE; FORCED EXPIRATORY VOLUME; HUMAN; LOGISTIC REGRESSION ANALYSIS; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; MULTIVARIATE LOGISTIC REGRESSION ANALYSIS; OBESITY; POPULATION; RISK FACTOR; SKIN TEST; SPAIN; SPIROMETRY;

ADULT; ASTHMA; BODY MASS INDEX; CROSS-SECTIONAL STUDIES; FEMALE; HUMANS; HYPERSENSITIVITY, IMMEDIATE; MALE; MIDDLE AGED; OBESITY; ODDS RATIO; RISK FACTORS; SEX FACTORS; SKIN TESTS; SMOKING; SPAIN; YOUNG ADULT;

EID: 70449635692     PISSN: 02770903     EISSN: 15324303     Source Type: Journal    
DOI: 10.3109/02770900903225386     Document Type: Article

References (39)

1. Hedley AA, Orden CL, Jonson CL, Carrol MD, Curtis LR, Flegal KM. Prevalence of overweight and obesity among US children, adolescents and adults. 1999-2002. JAMA 2004; 291:2847-2850.
2. Delgado J, Barranco P, Quirce S. Obesity and Asthma. J Invest Allergol Clin Immunol 2008;18:420-425.
3. Health, United States, 2005. Hyattsville, MD: National Center for Health Statistics, December 8, 2005:63.
4. Urrutia I, Aguirre U, Sunyer J, Plana E, Muniozguren N, Mart́nez-Moratalla J. Cambios en la poblacíon espanola del Estudio de Salud Respiratoria de la Comunidad Europea (ECRHS-II). Arch Brononeumol 2007; 43:425-430.
5. Camargo CA, Weiss ST, Zhang S, Willett WC, Speizer FE. Prospective study of body mass index, weight change, and risk of adult-onset asthma in women. Arch Intern Med 1999; 159:2582-2588.
6. Chen Y, Dales R, Tang M, Krewstic D. Obesity may increase the incidence of asthma in women but not in men: Longitudinal observations from the Canadian National Population Health surveys. Am J Epidemiol 2002; 155:191-197.
7. Ford ES,Mannino DM, Redd SC, Mokdad AM, Mott JA. Body mass index and asthma incidence among USA adults. Eur Respir J 2004; 24:740-744.
8. Gunnbörnsd́ottir MI, Omenaas E, Ǵslason T, Norrman E, Olin AC, Jögi R, Jensen EJ, Lindberg E, Björnsson E, Franklin K, Janson C, Gulsvik A, Laerum B, SVanes C, Toŕen K, Tunsäter A, Lillienberg L, Ǵslason D, Blöndal T, Björnsdottir US, Jörundsd́ottir KB, Talvik R, Forsberg B, Franklin K, Lundbäck B, Söderberg M, Ledin MC, Boman G, Norbäck D, Wieslander G, Spetz-Nyström U, Cashelunge KS, Ryd́en E, RHINE Study Group. Obesity and nocturnal gastro-oesophageal reflux are related to onset of asthma and respiratory symptoms. Eur Respir J 2004; 24:116-121.
9. Huovinen E, Kaprio J, Laitinen LA, Kockenvuo M. Incidence and prevalence of asthma among adult Finnish men and women of the Finnish Twin Cohort from 1975 to 1990 and their relation to hay fever and chronic bronchitis. Chest 1999;115:928-936.
10. Nystad W, Meyer HE, Nafstad P, Iverdal A, Engeland A. Body mass index in relation to adult asthma among 135,000 Norwegian men and women. Am J Epidemiol 2004; 160:969-976. (Pubitemid 39488425)
11. Sutherland ER. Obesity and Asthma. Immunol Allergy Clin North Am 2008; 28:589-602.
12. Flaherman V, Rutherford GW. A meta-analysis of the effect of high weight on asthma. Arch Dis Child 2006; 9:334-339.
13. Beuther DA, Sutherland ER. Overweight, obesity and incident asthma: A meta-analysis of prospective epidemiologic studies. Am J Respir Crit Care Med 2007; 175:661-666.
14. Ford ES. The epidemiology of obesity and asthma. J Allergy Clin Immunol 2005; 115:897-909.
15. Shore SA, Jonhston RA. Obesity and Asthma. Pharmacol Ther 2006; 110:83-102.
16. Shore SA. Obesity and asthma: Possible mechanisms. J Allergy Clin Immunol 2008; 121:1087-1093.
17. Litonjua AA, Gold DR. Asthma and Obesity: Common early-life influences in the inception of disease. J Allergy Clin Immunol 2008; 121:1075-1084.
18. Brisbon N, Plumb J, Brawer R, Paxman D. The asthma and obesity epidemics: The role played by the built environment-a public health perspective. J Allergy Clin Immunol 2005; 115:1024-1028.
19. American Thoracic Society. Lung function testing: Selection of reference values and interpretative strategies. Am Rev Respir Dis 1991;144:1202-1218.
20. Crapo RO, Casaburi R, Coates AL, Enright PL, Hankinson JL, Irvin CG, MacIntyre NR, McKay RT,Wanger JS, Anderson SD, Cockcroft DW, Fish JE, Sterk PJ. Guidelines for methacholine and exercise challenge testing- 1999. Am J Respir Crit Care Med 2000; 161:309-329.
21. American Thoracic Society: Medical Section of the American Lung Association. Standarization of Spirometry. Am J Respir Crit Care Med 1995; 152:1107-1136.
22. Chatham M, Bleecker ER, Norman P, Smith PL, Mason P. A screening test for airways reactivity: An abbreviated methacholine inhalation challenge. Chest 1982; 82:15-18.
23. Quanjer PH, Tammeling GJ, Cotes JE, Pedersen OF, Peslin R, Yernault JC. Lung volumes and forced ventilatory flows. Report Working Party Standardization of Lung Function Tests, European Community for Steel and Coal. Official Statement of the European Respiratory Society. Eur Respir J Suppl 1993;16:5-40.
24. The ENFUMOSA cross-sectional European multicentre study of the clinical phenotype of chronic severe asthma. European Network for Understanding Mechanisms of Severe Asthma. Eur Respir J 2003;22:470-477.
25. Wenzel SE, Busse WW. Severe asthma: Lessons from the Severe Asthma Research Program. J Allergy Clin Immunol 2007;119:14-21.
26. Chinn S, Jarvis D, Burney P. Relation of bronchial responsiveness to body mass index in the ECRHS. European Community Respiratory Health Survey. Thorax 2002; 57:1028-1033.
27. Litonjua AA, Sparrow D, Celedon JC, DeMolles D, Weiss ST. Association of body mass index with the development of methacholine airway hyperresponsiveness in men: The Normative Aging Study. Thorax 2002; 57:581-585.
28. Schachter LM, Salome CM, Peat JK, Woolcock AJ. Obesity is a risk for asthma and wheeze but not airway hyperresponsiveness. Thorax 2001; 56:4-8.
29. Tansisira KG, Litonjua AA, Weiss ST, Fuhlbrigge AL, for the Childhood Asthma Management Program Research Group. Association of body mass with pulmonary function in the Childhood Asthma Management Program (CAMP). Thorax 2003; 58:1036-1041.
30. Sutherland TJT, Cowan JO, Taylor DR. Dynamic hyperinflation with bronchoconstriction. Differences between obese and nonobese women with Asthma. Am J Respir Crit Care Med 2008; 177:970-975.
31. Salome CM, Munoz PA, Berend N, Thorpe CW, Schachter LM, King GG. Effect of obesity on breathlessness and airway responsiveness to methacholine in non-asthmatic subjects. Int J Obes (Lond) 2008; 32:502-509.
32. Machado D, Tavares B, Loureiro G, Conde B, Cemlyn-Jones J, Calado G, Sousa N, Chieira C, Pereira C. Body mas index and airway hyperresponsiveness in individuals without respiratory disease. Eur Ann Allergy Clin Immunol 2008; 40:130-137.
33. Wang LY, Cerny FJ, Kufel TJ, Grant BJB. Simulated obesity-related changes in lung volume increases airway responsiveness in lean, nonasthmatic subjects. Chest 2006; 130:834-840.
34. Chen Y, Dales R, Tang M, Krewski D. Obesity may increase the incidence of asthma in women but not in men: Longitudinal observations from the Canadian National Population Health Surveys. Am J Epidemiol 2002; 155:191-197.
35. Shore SA, Johnston RA. Obesity and asthma. Pharmacol Ther 2006; 110:83-102.
36. Shore SA. Obesity and asthma: Possible mechanisms. J Allergy Clin Immunol 2008; 121:1087-1093.
37. Nair PN, Radford K, Fanat A, Janssen LJ, Peters-Golden, Cox PG. The effects of leptin on airway smooth muscle responses. Am J Respir Cell Mol Biol 2008; 39:475-481.
38. Medoff BD, Okamoto Y, Leyton P,WengM, Sandall BP, Raher MJ, Kihara S, Bloch HD, Libby P, Luster AD. Adiponectin-deficiency increases allergy airway inflammation and pulmonary vascular remodeling.AmJ Respir Cell Mol Biol 2009; 23 [Epub ahead of print].
39. Aaron SD, Vandemheen KL, Boulet LP,McIvor RA, Fizgerald JM, Hernandez P, Lemiere C, Sharma S, Field SK, Alvarez GG, Dales RE, Doucette S, Fergusson D; Canadian Respiratory Clinical Research Consortium. Overdiagnosis of asthma in obese and nonobese adults. CMAJ 2008;179:1121-1131.