Comparative analysis of cell proliferation ratio in oral lichen planus, epithelial dysplasia and oral squamous cell carcinoma

Medicina Oral, Patologia Oral y Cirugia Bucal

Volumn 14, Issue 11, 2009, Pages

  De Sousa, Fernando Augusto Cervantes Garcia ^a   Paradella, Thaís Cachuté ^a   Carvalho, Yasmin Rodarte ^a   Rosa, Luiz Eduardo Blumer ^a  

^a SÃO PAULO STATE UNIVERSITY UNESP   (Brazil)

Author keywords

Agnor; Epithelial dysplasia; Immunohistochemistry; Oral lichen planus; Oral squamous cell carcinoma

Indexed keywords

BIOTIN; CYCLINE;

ANALYSIS OF VARIANCE; ARTICLE; CELL PROLIFERATION; CHI SQUARE TEST; CHROMOSOME NOR; COMPARATIVE STUDY; DYSPLASIA; HUMAN; IMMUNOHISTOCHEMISTRY; LICHEN PLANUS; MALIGNANT TRANSFORMATION; MOUTH CARCINOMA; SQUAMOUS CELL CARCINOMA;

CARCINOMA, SQUAMOUS CELL; CELL PROLIFERATION; HUMANS; LICHEN PLANUS, ORAL; MOUTH MUCOSA; MOUTH NEOPLASMS;

EID: 70449602673     PISSN: 16984447     EISSN: 16986946     Source Type: Journal    
DOI: 10.4317/medoral.14.e563     Document Type: Article

References (19)

1. Miyachi K, Fritzler MJ, Tan EM. Autoantibody to a nuclear antigen in proliferating cells. J Immunol. 1978;121:2228-2234 (Pubitemid 9075187)
2. McCormick D, Hall PA. The complexities of proliferating cell nuclear antigen. Histopathology. 1992;21:591-594 (Pubitemid 23005758)
3. Hall PA, Levison DA, Woods AL, Yu CC, Kellock DB, Watkins JA, et al. Proliferating cell nuclear antigen (PCNA) immunolocalization in paraffin sections: an index of cell proliferation with evidence of deregulated expression in some neoplasms. J Pathol. 1990;162:285-294
4. Tsuji T, Mimura Y, Wen S, Li X, Kanekawa A, Sasaki K, et al. The significance of PCNA and p53 protein in some oral tumors. Int J Oral Maxillofac Surg. 1995;24:221-225
5. Derenzini M. The AgNORs. Micron. 2000;31:117-120
6. Elangovan T, Mani NJ, Malathi N. Argyrophilic nucleolar organizer regions in inflammatory, premalignant, and malignant oral lesions: a quantitative and qualitative assessment. Indian J Dent Res. 2008;19:141-146
7. Derenzini M, Trerè D. AgNOR proteins as a parameter of the rapidity of cell proliferation. Zentralbl Pathol. 1994;140:7-10.
8. Trerè D, Farabegoli F, Cancellieri A, Ceccarelli C, Eusebi V, Derenzini M. AgNOR area in interphase nuclei of human tumours correlates with the proliferative activity evaluated by bromodeoxyuridine labelling and Ki-67 immunostaining. J Pathol. 1991;165:53-59
9. Van der Waal I. Potentially malignant disorders of the oral and oropharyngeal mucosa; terminology, classification and present concepts of management. Oral Oncol. 2009;45:317-323
10. Van der Meij EH, Schepman KP, Smeele LE, Van der Wal JE, Bezemer PD, Van der Waal I. A review of the recent literature regarding malignant transformation of oral lichen planus. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1999;88:307-310
11. Eisenberg E. Oral lichen planus: a benign lesion. J Oral Maxillofac Surg. 2000;58:1278-1285 (Pubitemid 30812861)
12. Gonzalez-Moles MA, Scully C, Gil-Montoya JA. Oral lichen planus: controversies surrounding malignant transformation. Oral Dis. 2008;14:229-243
13. Ploton D, Menager M, Jeannesson P, Himber G, Pigeon F, Adnet JJ. Improvement in the staining and in the visualization of the argyrophilic proteins of the nucleolar organizer region at the optical level. Histochem J. 1986;18:5-14. (Pubitemid 16108305)
14. Lee JJ, Kuo MY, Cheng SJ, Chiang CP, Jeng JH, Chang HH, et al. Higher expressions of p53 and proliferating cell nuclear antigen (PCNA) in atrophic oral lichen planus and patients with areca quid chewing. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2005;99:471-478
15. Da Silva Fonseca LM, Do Carmo MA. Identification of the Ag- NORs, PCNA and ck16 proteins in oral lichen planus lesions. Oral Dis. 2001;7:344-348
16. González-Moles MA, Bascones-Ilundain C, Gil Montoya JA, Ruiz-Avila I, Delgado-Rodríguez M, Bascones-Martínez A. Cell cycle regulating mechanisms in oral lichen planus: molecular bases in epithelium predisposed to malignant transformation. Arch Oral Biol. 2006;51:1093-1103 (Pubitemid 44692650)
17. Xie X, Clausen OP, Sudbö J, Boysen M. Diagnostic and prognostic value of nucleolar organizer regions in normal epithelium, dysplasia, and squamous cell carcinoma of the oral cavity. Cancer. 1997;79:2200-2208 (Pubitemid 27227386)
18. Ray JG, Chattopadhyay A, Caplan DJ. Usefulness of AgNOR counts in diagnosing epithelial dysplasia. J Oral Pathol Med. 2003;32:71-76 (Pubitemid 36604032)
19. Cano Montoya LC, Alvarez Gómez GJ, Valencia Londoño WA, Ramírez España JA, Prada Navas CA. Analysis of the tissue marker AgNOR in leukoplaquia and oral squamous cell carcinoma. Med Oral. 2002;7:17-21, 22-25