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Volumn 64, Issue 9-10, 2009, Pages 619-625

Pharmacological evaluation of novel indole-2-carboxamides as potent lipid-lowering agents in triton-WR-1339-induced hyperlipidemic rats

Author keywords

Antihyperlipidemic activity; BMI2C N (4 Benzoylphenyl) 5 methoxy 1H indole 2 carboxamide ; DDMI2C N (9,10 Dihydro 9,10 dioxoanthracen 2 yl) 5 methoxy 1H indole 2 carboxamide

Indexed keywords

RATTUS;

EID: 70449591816     PISSN: 09395075     EISSN: None     Source Type: Journal    
DOI: 10.1515/znc-2009-9-1003     Document Type: Article
Times cited : (16)

References (30)
  • 1
    • 0036136676 scopus 로고    scopus 로고
    • Flavonoids from Emblica officinalis and Mangifera indica-effectiveness for dyslipidemia
    • Anila L. and Vijayalakshmi N. R. (2002), Flavonoids from Emblica officinalis and Mangifera indica-effectiveness for dyslipidemia. J. Ethnopharmacol. 79, 81-87.
    • (2002) J. Ethnopharmacol , vol.79 , pp. 81-87
    • Anila, L.1    Vijayalakshmi, N.R.2
  • 2
    • 0031826626 scopus 로고    scopus 로고
    • Lipid-lowering drugs in the management of hyperlipidemia
    • Bhatnagar D. (1998), Lipid-lowering drugs in the management of hyperlipidemia. Pharmacol. Therapeut. 79, 205-230.
    • (1998) Pharmacol. Therapeut , vol.79 , pp. 205-230
    • Bhatnagar, D.1
  • 3
    • 70449617025 scopus 로고
    • Hypoglycemically and hypolipidemically active derivatives of phenylalkane carboxylic acids
    • 150207
    • Bosies E., Heerdt R., Kuknle H. F., Schmidt F. H., and Stach H. (1980), Hypoglycemically and hypolipidemically active derivatives of phenylalkane carboxylic acids. US Patent 150207.
    • (1980) US Patent
    • Bosies, E.1    Heerdt, R.2    Kuknle, H.F.3    Schmidt, F.H.4    Stach, H.5
  • 4
    • 0342427144 scopus 로고
    • Ficus carica leaf administration reduces hypertriglyceridaemia in streptozocin diabetic rats
    • Campillo J. E., Torres M. D., Dominguez E., Romero A., and Pérez C. (1994), Ficus carica leaf administration reduces hypertriglyceridaemia in streptozocin diabetic rats. Diabetologia 37, A213.
    • (1994) Diabetologia , vol.37
    • Campillo, J.E.1    Torres, M.D.2    Dominguez, E.3    Romero, A.4    Pérez, C.5
  • 5
    • 77954994164 scopus 로고    scopus 로고
    • Aliphatic, aromatic, and heterocyclic ketone compounds and compositions for cholesterol management and related uses
    • 325529
    • Dasseux J.-L.H. and Oniciu C. D. (2002), Aliphatic, aromatic, and heterocyclic ketone compounds and compositions for cholesterol management and related uses. US Patent 325529.
    • (2002) US Patent
    • Dasseux, J.-L.H.1    Oniciu, C.D.2
  • 6
    • 0015973643 scopus 로고
    • Triglyceride secretion rates: Use of Triton in the rhesus monkey
    • Fiser R. H., Denniston J. C., Rindsig R. B., and Beisel W. R. (1974), Triglyceride secretion rates: use of Triton in the rhesus monkey. J. Nutr. 104, 223-226.
    • (1974) J. Nutr , vol.104 , pp. 223-226
    • Fiser, R.H.1    Denniston, J.C.2    Rindsig, R.B.3    Beisel, W.R.4
  • 8
    • 0031856531 scopus 로고    scopus 로고
    • Biologic markers as predictors of cardiovascular disease
    • Frishman W. H. (1998), Biologic markers as predictors of cardiovascular disease. Am. J. Med. 104, 18S-27S.
    • (1998) Am. J. Med , vol.104
    • Frishman, W.H.1
  • 9
    • 0031300491 scopus 로고    scopus 로고
    • Elevation of plasma lipid peroxides in non-insulin dependent diabetics with multiple lacunar infarcts
    • Tagami S., and Kawakami Y
    • Fujiwara Y., Nishihara H., Nakakoshi T., Hasegawa T., Tagami S., and Kawakami Y. (1997), Elevation of plasma lipid peroxides in non-insulin dependent diabetics with multiple lacunar infarcts. J. Atheroscler. Thromb. 4, 90-95.
    • (1997) Hasegawa T , vol.4 , pp. 90-95
    • Fujiwara, Y.1    Nishihara, H.2    Nakakoshi, T.3
  • 10
    • 0035873253 scopus 로고    scopus 로고
    • Hypertriglyceridemia: New in- sights and new approaches to pharmacologic therapy
    • Ginsberg H. N. (2001), Hypertriglyceridemia: new in- sights and new approaches to pharmacologic therapy. Am. J. Cardiol. 87, 1174-1180.
    • (2001) Am. J. Cardiol , vol.87 , pp. 1174-1180
    • Ginsberg, H.N.1
  • 11
    • 0034703629 scopus 로고    scopus 로고
    • Differential expression of lipoprotein lipase gene in tissues of the rat model with visceral obesity and postprandial hyperlipidemia
    • Hikita M., Bujo H., Yamazaki K., Taira K., Takahashi K., Kobayashi J., and Saito Y. (2000), Differential ex- pression of lipoprotein lipase gene in tissues of the rat model with visceral obesity and postprandial hyperlipidemia. Biochem. Biophys. Res. Commun. 277, 423-429.
    • (2000) Biochem. Biophys. Res. Commun , vol.277 , pp. 423-429
    • Hikita, M.1    Bujo, H.2    Yamazaki, K.3    Taira, K.4    Takahashi, K.5    Kobayashi, J.6    Saito, Y.7
  • 12
    • 0018758240 scopus 로고
    • Changes in the concentration of plasma lipoproteins and apoproteins following the administration of Triton WR 1339 to rats
    • Ishikawa T. and Fidge N. (1979), Changes in the concentration of plasma lipoproteins and apoproteins following the administration of Triton WR 1339 to rats. J. Lipid Res. 20, 254-264.
    • (1979) J. Lipid Res , vol.20 , pp. 254-264
    • Ishikawa, T.1    Fidge, N.2
  • 14
    • 0000801522 scopus 로고
    • Sustained hyperlipemia induced in rabbits by means of intravenously injected surface-active agents
    • Kellner A., Correll J. W., and Ladd A. T. (1951), Sustained hyperlipemia induced in rabbits by means of intravenously injected surface-active agents. J. Exp. Med. 93, 373-384.
    • (1951) J. Exp. Med , vol.93 , pp. 373-384
    • Kellner, A.1    Correll, J.W.2    Ladd, A.T.3
  • 15
    • 0026814207 scopus 로고
    • Hypolipidemic activ- ity of Achyranthus aspera Linn. in normal and Triton induced hyperlipemic rats
    • Khanna A. K., Chauder R., Chandan S., Srivastava A. K., and Kapoor N. K. (1992), Hypolipidemic activity of Achyranthus aspera Linn. in normal and Triton induced hyperlipemic rats. Indian. J. Exp. Biol. 30, 128-130.
    • (1992) Indian. J. Exp. Biol , vol.30 , pp. 128-130
    • Khanna, A.K.1    Chauder, R.2    Chandan, S.3    Srivastava, A.K.4    Kapoor, N.K.5
  • 16
    • 0036708094 scopus 로고    scopus 로고
    • Lipid lowering activity of Phyllanthus niruri in hyperlipemic rats
    • Khanna A. K., Rizvi F., and Chander R. (2002), Lipid lowering activity of Phyllanthus niruri in hyperlipemic rats. J. Ethnopharmacol. 82, 19-22.
    • (2002) J. Ethnopharmacol , vol.82 , pp. 19-22
    • Khanna, A.K.1    Rizvi, F.2    Chander, R.3
  • 17
    • 70449606292 scopus 로고    scopus 로고
    • Altering intestinal motility and absorption of hydrophobic compounds through the use of agonists and/or antagonists of the cholecystokinin-1 receptor
    • 224869
    • Kopin A. S., Carey M., and Wang D. (2006), Altering intestinal motility and absorption of hydrophobic compounds through the use of agonists and/or an- tagonists of the cholecystokinin-1 receptor. US Patent 224869.
    • (2006) US Patent
    • Kopin, A.S.1    Carey, M.2    Wang, D.3
  • 18
    • 0024832784 scopus 로고
    • Mucuma pruriens infusion lowers cholesterol and total lipid plasma levels in the rats
    • Lauk L., Galati E.M., Forestieri A. M., Kirjavainen S., and Trovato A. (1989), Mucuma pruriens infusion lowers cholesterol and total lipid plasma levels in the rats. Phytother. Res. 3, 263-264.
    • (1989) Phytother. Res , vol.3 , pp. 263-264
    • Lauk, L.1    Galati, E.M.2    Forestieri, A.M.3    Kirjavainen, S.4    Trovato, A.5
  • 19
    • 0028188438 scopus 로고
    • Medical-management of hyperlipidemic states
    • Malloy M. J. and Kan J. P. (1994), Medical-management of hyperlipidemic states. Adv. Int. Med. 39, 603-631.
    • (1994) Adv. Int. Med , vol.39 , pp. 603-631
    • Malloy, M.J.1    Kan, J.P.2
  • 20
    • 0034575092 scopus 로고    scopus 로고
    • Effect of bezafibrate or pravastatin on serum lipid levels and albuminuria in NIDDM patients
    • Nagai T., Tomizawa T., Nakajima K., and Mori M. (2000), Effect of bezafibrate or pravastatin on serum lipid levels and albuminuria in NIDDM patients. J. Atheroscler. Thromb. 7, 91-96.
    • (2000) J. Atheroscler. Thromb , vol.7 , pp. 91-96
    • Nagai, T.1    Tomizawa, T.2    Nakajima, K.3    Mori, M.4
  • 21
    • 0034570664 scopus 로고    scopus 로고
    • Effect of bezafibrate treatment on the altered lipoprotein profiles in hypertriglyceridemic subjects
    • Norioka M., Suzuki M., Ryomoto K., Ikebuchi M., and Harano Y. (2000), Effect of bezafibrate treatment on the altered lipoprotein profiles in hypertriglyceridemic subjects. J. Atheroscler. Thromb. 7, 198-202
    • (2000) J. Atheroscler. Thromb , vol.7 , pp. 198-202
    • Norioka, M.1    Suzuki, M.2    Ryomoto, K.3    Ikebuchi, M.4    Harano, Y.5
  • 22
    • 0014086975 scopus 로고
    • The effect of the nonionic detergent (Triton) on the removal of tri- glyceride fatty acids from the blood of the rats
    • Otway S. and Robinson D. S. (1967), The effect of the nonionic detergent (Triton) on the removal of triglyceride fatty acids from the blood of the rats. J. Physiol. 190, 309-319.
    • (1967) J. Physiol , vol.190 , pp. 309-319
    • Otway, S.1    Robinson, D.S.2
  • 23
    • 0032892648 scopus 로고    scopus 로고
    • Hypotriglyceridemic activity of Ficus carica leaves in experimental hypertriglyceri- demic rats
    • Pérez C., Canal J. R., Campello J. E., Adelaida R., and Torres M. D. (1999), Hypotriglyceridemic activity of Ficus carica leaves in experimental hypertriglyceridemic rats. Phytother. Res. 13, 188-191.
    • (1999) Phytother. Res , vol.13 , pp. 188-191
    • Pérez, C.1    Canal, J.R.2    Campello, J.E.3    Adelaida, R.4    Torres, M.D.5
  • 25
    • 0029994543 scopus 로고    scopus 로고
    • Role of the peroxisome proliferator-activated receptor (PPAR) in mediating the effects of fibrates and fatty acids on gene expression
    • Schoonjans K., Staels B., and Auwerx J. (1996), Role of the peroxisome proliferator-activated receptor (PPAR) in mediating the effects of fibrates and fatty acids on gene expression. J. Lipid Res. 37, 907-925.
    • (1996) J. Lipid Res , vol.37 , pp. 907-925
    • Schoonjans, K.1    Staels, B.2    Auwerx, J.3
  • 26
    • 0000434495 scopus 로고
    • Effect of Triton on lipoprotein lipase of rat plasma
    • Schotz M. C., Scanu A., and Page I. H. (1957), Effect of Triton on lipoprotein lipase of rat plasma. Am. J. Physiol. 188, 399-402.
    • (1957) Am. J. Physiol , vol.188 , pp. 399-402
    • Schotz, M.C.1    Scanu, A.2    Page, I.H.3
  • 27
    • 0015254532 scopus 로고
    • Triton induced hyperlipidaemia in rats as an animal model for screening hypolipidaemic drugs
    • Schurr P. E., Schultz J. R., and Parkinson T. M. (1972), Triton induced hyperlipidaemia in rats as an animal model for screening hypolipidaemic drugs. Lipids 7, 69-74.
    • (1972) Lipids , vol.7 , pp. 69-74
    • Schurr, P.E.1    Schultz, J.R.2    Parkinson, T.M.3
  • 28
    • 70449621807 scopus 로고    scopus 로고
    • Triglyceride and triglyceride-like prodrugs of glycogen phosphorylase inhibiting compounds
    • 140474
    • Sher P. M. and Ellsworth B. A. (2004), Triglyceride and triglyceride-like prodrugs of glycogen phosphorylase inhibiting compounds. US Patent 140474.
    • (2004) US Patent
    • Sher, P.M.1    Ellsworth, B.A.2
  • 29
    • 0029661991 scopus 로고    scopus 로고
    • Lipid management: Current diet and drug treatment options
    • Stone N. J. (1996), Lipid management: current diet and drug treatment options. Am. J. Med. 101, 40S-49S.
    • (1996) Am. J. Med , vol.101
    • Stone, N.J.1
  • 30
    • 0031313178 scopus 로고    scopus 로고
    • Influence of apolipoprotein E polymorphism on bezafibrate treatment response in dyslipidemic patients
    • Yamada M. (1997), Influence of apolipoprotein E polymorphism on bezafibrate treatment response in dyslipidemic patients. J. Atheroscler. Thromb. 4, 40-44.
    • (1997) J. Atheroscler. Thromb , vol.4 , pp. 40-44
    • Yamada, M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.