Erratum: Fyn Mediates Leptin Actions in the Thymus of Rodents(Fyn Mediates Leptin Actions in the Thymus of Rodents. (2009) 4:11 (e7707) DOI: 10.1371/journal.pone.0007707);Fyn mediates leptin actions in the thymus of rodents

PLoS ONE

Volumn 4, Issue 11, 2009, Pages

  Girasol, Alessandra ^a   Albuquerque, Gabriela G ^a   Mansour, Eli ^a   Araújo, Eliana P ^a   Degasperi, Giovanna ^a   Denis, Raphael G ^a   Carvalheira, José B ^a   Saad, Mário J ^a   Velloso, Lício A ^a  

^a UNIVERSITY OF CAMPINAS   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; INSULIN RECEPTOR SUBSTRATE 1; JANUS KINASE 2; LEPTIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE FYN; FYN PROTEIN, HUMAN; LEPTIN RECEPTOR;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; FLOW CYTOMETRY; IMMUNOBLOTTING; IMMUNOMODULATION; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION; RAT; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; THYMOCYTE; THYMUS; ANIMAL; C57BL MOUSE; CELL SEPARATION; CYTOLOGY; GENE EXPRESSION REGULATION; METABOLISM; MOUSE; PHYSIOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WISTAR RAT;

RODENTIA;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; CELL SEPARATION; GENE EXPRESSION REGULATION; LEPTIN; MALE; MICE; MICE, INBRED C57BL; PROTO-ONCOGENE PROTEINS C-FYN; RATS; RATS, WISTAR; RECEPTORS, LEPTIN; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; THYMUS GLAND;

EID: 70449564341     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0281409     Document Type: Erratum

References (34)

1. Fernandes G (2008) Progress in nutritional immunology. Immunol Res 40: 244-261.
2. Ahluwalia N (2004) Aging, nutrition and immune function. J Nutr Health Aging 8: 2-6.
3. Lesourd BM, Mazari L, Ferry M (1998) The role of nutrition in immunity in the aged. Nutr Rev 56: S113-125.
4. Valdes-Ramos R, Benitez-Arciniega AD (2007) Nutrition and immunity in cancer. Br J Nutr 98 Suppl 1: S127-132.
5. Matarese G, Moschos S, Mantzoros CS (2005) Leptin in immunology. J Immunol 174: 3137-3142.
6. Flier JS (1998) Lowered leptin slims immune response. Nat Med 4: 1124-1125.
7. Friedman JM, Halaas JL (1998) Leptin and the regulation of body weight in mammals. Nature 395: 763-770.
8. Lord GM, Matarese G, Howard JK, Baker RJ, Bloom SR, et al. (1998) Leptin modulates the T-cell immune response and reverses starvation-induced immunosuppression. Nature 394: 897-901.
9. Howard JK, Lord GM, Matarese G, Vendetti S, Ghatei MA, et al. (1999) Leptin protects mice from starvation-induced lymphoid atrophy and increases thymic cellularity in ob/ob mice. J Clin Invest 104: 1051-1059.
10. Farooqi IS, Matarese G, Lord GM, Keogh JM, Lawrence E, et al. (2002) Beneficial effects of leptin on obesity, T cell hyporesponsiveness, and neuroendocrine/metabolic dysfunction of human congenital leptin deficiency. J Clin Invest 110: 1093-1103.
11. Mansour E, Pereira FG, Araujo EP, Amaral ME, Morari J, et al. (2006) Leptin inhibits apoptosis in thymus through a janus kinase-2-independent, insulin receptor substrate-1/ phosphatidylinositol-3 kinase-dependent pathway. Endocrinology 147: 5470-5479.
12. Velloso LA, Savino W, Mansour E (2009) Leptin action in the thymus. Ann N Y Acad Sci 1153: 29-34.
13. Gasparetti AL, de Souza CT, Pereira-da-Silva M, Oliveira RL, Saad MJ, et al. (2003) Cold exposure induces tissue-specific modulation of the insulin-signalling pathway in Rattus norvegicus. J Physiol 552: 149-162.
14. Boyum A (1976) Isolation of lymphocytes, granulocytes and macrophages. Scand J Immunol Suppl 5: 9-15.
15. Degasperi GR, Zecchin KG, Borecky J, Cruz-Hofling MA, Castilho RF, et al. (2006) Verapamil-sensitive Ca2+ channel regulation of Th1-type proliferation of splenic lymphocytes induced by Walker 256 tumor development in rats. Eur J Pharmacol 549: 179-184.
16. Brumatti G, Weinlich R, Chehab CF, Yon M, Amarante-Mendes GP (2003) Comparison of the anti-apoptotic effects of Bcr-Abl, Bcl-2 and Bcl-x(L) following diverse apoptogenic stimuli. FEBS Lett 541: 57-63.
17. Jiang L, Li Z, Rui L (2008) Leptin stimulates both JAK2-dependent and JAK2-independent signaling pathways. J Biol Chem 283: 28066-28073.
18. Taga T, Kishimoto T (1997) Gp130 and the interleukin-6 family of cytokines. Annu Rev Immunol 15: 797-819.
19. Tartaglia LA (1997) The leptin receptor. J Biol Chem 272: 6093-6096.
20. Kloek C, Haq AK, Dunn SL, Lavery HJ, Banks AS, et al. (2002) Regulation of Jak kinases by intracellular leptin receptor sequences. J Biol Chem 277: 41547-41555.
21. Banks AS, Davis SM, Bates SH, Myers MG, Jr. (2000) Activation of downstream signals by the long form of the leptin receptor. J Biol Chem 275: 14563-14572.
22. Myers MG, Cowley MA, Munzberg H (2008) Mechanisms of leptin action and leptin resistance. Annu Rev Physiol 70: 537-556.
23. Velloso LA, Araujo EP, de Souza CT (2008) Diet-induced inflammation of the hypothalamus in obesity. Neuroimmunomodulation 15: 189-193.
24. Stein PL, Lee HM, Rich S, Soriano P (1992) pp59fyn mutant mice display differential signaling in thymocytes and peripheral T cells. Cell 70: 741-750.
25. Olszowy MW, Leuchtmann PL, Veillette A, Shaw AS (1995) Comparison of p56lck and p59fyn protein expression in thymocyte subsets, peripheral T cells, NK cells, and lymphoid cell lines. J Immunol 155: 4236-4240.
26. Utting O, Teh SJ, Teh HS (1998) T cells expressing receptors of different affinity for antigen ligands reveal a unique role for p59fyn in T cell development and optimal stimulation of T cells by antigen. J Immunol 160: 5410-5419.
27. Salmond RJ, Filby A, Qureshi I, Caserta S, Zamoyska R (2009) T-cell receptor proximal signaling via the Src-family kinases, Lck and Fyn, influences T-cell activation, differentiation, and tolerance. Immunol Rev 228: 9-22.
28. Kellerer M, Koch M, Metzinger E, Mushack J, Capp E, et al. (1997) Leptin activates PI-3 kinase in C2C12 myotubes via janus kinase-2 (JAK-2) and insulin receptor substrate-2 (IRS-2) dependent pathways. Diabetologia 40: 1358-1362.
29. Carvalheira JB, Siloto RM, Ignacchitti I, Brenelli SL, Carvalho CR, et al. (2001) Insulin modulates leptin-induced STAT3 activation in rat hypothalamus. FEBS Lett 500: 119-124.
30. Munzberg H, Myers MG, Jr. (2005) Molecular and anatomical determinants of central leptin resistance. Nat Neurosci 8: 566-570.
31. Chung WK, Power-Kehoe L, Chua M, Leibel RL (1996) Mapping of the OB receptor to 1p in a region of nonconserved gene order from mouse and rat to human. Genome Res 6: 431-438.
32. Savino W, Dardenne M, Velloso LA, Dayse Silva-Barbosa S (2007) The thymus is a common target in malnutrition and infection. Br J Nutr 98 Suppl 1: S11-16.
33. Matarese G, Di Giacomo A, Sanna V, Lord GM, Howard JK, et al. (2001) Requirement for leptin in the induction and progression of autoimmune encephalomyelitis. J Immunol 166: 5909-5916.
34. La Cava A, Matarese G (2004) The weight of leptin in immunity. Nat Rev Immunol 4: 371-379.