Reverse engineering and verification of gene networks: Principles, assumptions, and limitations of present methods and future perspectives

Journal of Biotechnology

Volumn 144, Issue 3, 2009, Pages 190-203

  He, Feng ^a   Balling, Rudi ^a   Zeng, An Ping ^a,b  

^a HELMHOLTZ CENTRE FOR INFECTION RESEARCH   (Germany)

^b HAMBURG UNIVERSITY OF TECHNOLOGY   (Germany)

Author keywords

Gene network; Optimal experimental design; Pair wise functional association linkage; Reverse engineering; Systems biology; Time series expression dynamics

Indexed keywords

EXPERIMENTAL DATA; EXPERIMENTAL VERIFICATION; EXPRESSION DATA; FUTURE PERSPECTIVES; GENE NETWORK; GENE NETWORKS; GENE REGULATION NETWORK; GENE TRANSCRIPTS; NETWORK STRUCTURES; OPTIMAL EXPERIMENTAL DESIGN; OPTIMAL EXPERIMENTAL DESIGNS; PAIR WISE FUNCTIONAL ASSOCIATION LINKAGE; SAMPLING SCHEDULE; SYSTEMS BIOLOGY;

BIOLOGICAL SYSTEMS; FORCE MEASUREMENT; OPTIMIZATION; REENGINEERING; TIME SERIES;

REVERSE ENGINEERING;

MESSENGER RNA;

ARTICLE; BAYES THEOREM; BIOINFORMATICS; CELL CYCLE REGULATION; ESCHERICHIA COLI; GENE EXPRESSION; GENE REGULATORY NETWORK; GENETIC ENGINEERING; GENETIC LINKAGE; GENETIC TRANSCRIPTION; MATHEMATICAL MODEL; NONHUMAN; NORMAL DISTRIBUTION; PRIORITY JOURNAL; YEAST CELL;

ANIMALS; GENE REGULATORY NETWORKS; GENETIC ENGINEERING; HUMANS; REPRODUCIBILITY OF RESULTS;

EID: 70449529712     PISSN: 01681656     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jbiotec.2009.07.013     Document Type: Article

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