Direct Binding of Glyceraldehyde 3-Phosphate Dehydrogenase to Telomeric DNA Protects Telomeres against Chemotherapy-Induced Rapid Degradation

Journal of Molecular Biology

Volumn 394, Issue 4, 2009, Pages 789-803

  Demarse, Neil A ^a   Ponnusamy, Suriyan ^a,b   Spicer, Eleanor K ^a   Apohan, Elif ^a,b   Baatz, John E ^a   Ogretmen, Besim ^a,b   Davies, Christopher ^a  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^b MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

A549 lung carcinoma cells; chemotherapeutics; glycolytic enzyme; protection of telomeres; protein DNA interactions

Indexed keywords

CASPASE; DNA; DOXORUBICIN; GEMCITABINE; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; NICOTINAMIDE ADENINE DINUCLEOTIDE; OLIGONUCLEOTIDE; SINGLE STRANDED DNA; TELOMERIC DNA; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; BINDING AFFINITY; BINDING COMPETITION; BINDING SITE; CANCER CELL; CELL NUCLEUS; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME DEGRADATION; ENZYME LOCALIZATION; GROWTH INHIBITION; HUMAN; HUMAN CELL; LUNG ALVEOLUS EPITHELIUM; MOLECULAR WEIGHT; NONHUMAN; PRIORITY JOURNAL; PROTEIN DNA INTERACTION; SITE DIRECTED MUTAGENESIS; STOICHIOMETRY; TELOMERE;

EID: 70449525136     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2009.09.062     Document Type: Article

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