메뉴 건너뛰기




Volumn 124, Issue 6, 2009, Pages 711-713

Lack of change in insulin levels as a biological marker of PAI-1 lowering in GH-deficient adults on r-HGH replacement therapy

Author keywords

GH deficient adults; IGF 1; insulin; PAI 1; r HGH treatment; t PA

Indexed keywords

BIOLOGICAL MARKER; HUMAN GROWTH HORMONE; INSULIN; PLASMINOGEN ACTIVATOR INHIBITOR 1; SOMATOMEDIN C; TISSUE PLASMINOGEN ACTIVATOR;

EID: 70449522171     PISSN: 00493848     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.thromres.2009.06.018     Document Type: Article
Times cited : (10)

References (28)
  • 1
    • 18444413530 scopus 로고    scopus 로고
    • Hypopituitary Control and Complications Study International Advisory Board. Human growth hormone replacement in adult hypopituitary patients: long-term effects on body composition and lipid status-3-year results from the HypoCCS Database
    • Attanasio A.F., Bates P.C., Ho K.K., Webb S.M., Ross R.J., Strasburger C.J., et al. Hypopituitary Control and Complications Study International Advisory Board. Human growth hormone replacement in adult hypopituitary patients: long-term effects on body composition and lipid status-3-year results from the HypoCCS Database. J Clin Endocrinol Metab 87 (2002) 1600-1606
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 1600-1606
    • Attanasio, A.F.1    Bates, P.C.2    Ho, K.K.3    Webb, S.M.4    Ross, R.J.5    Strasburger, C.J.6
  • 2
    • 0031710787 scopus 로고    scopus 로고
    • Prevalence of insulin resistance in metabolic disorders: the Bruneck Study
    • Bonora E., Kiechl S., Willeit J., Oberhollenzer F., Egger G., Targher G., et al. Prevalence of insulin resistance in metabolic disorders: the Bruneck Study. Diabetes 47 (1998) 1643-1649
    • (1998) Diabetes , vol.47 , pp. 1643-1649
    • Bonora, E.1    Kiechl, S.2    Willeit, J.3    Oberhollenzer, F.4    Egger, G.5    Targher, G.6
  • 3
    • 17844368602 scopus 로고    scopus 로고
    • Short-term effects of growth hormone (GH) treatment or deprivation on cardiovascular risk parameters and intima-media thickness at carotid arteries in patients with severe GH deficiency
    • Colao A., Di Somma C., Rota F., Pivonello R., Savanelli M.C., Spiezia S., et al. Short-term effects of growth hormone (GH) treatment or deprivation on cardiovascular risk parameters and intima-media thickness at carotid arteries in patients with severe GH deficiency. J Clin Endocrinol Metab 90 (2005) 2056-2062
    • (2005) J Clin Endocrinol Metab , vol.90 , pp. 2056-2062
    • Colao, A.1    Di Somma, C.2    Rota, F.3    Pivonello, R.4    Savanelli, M.C.5    Spiezia, S.6
  • 4
    • 0030809467 scopus 로고    scopus 로고
    • Clinical relevance of polymorphic markers of arterial thrombosis
    • Di Minno G., Grandone E., and Margaglione M. Clinical relevance of polymorphic markers of arterial thrombosis. Thromb Haemostasis 78 (1997) 462-466
    • (1997) Thromb Haemostasis , vol.78 , pp. 462-466
    • Di Minno, G.1    Grandone, E.2    Margaglione, M.3
  • 5
    • 0034846917 scopus 로고    scopus 로고
    • Biochemical and biophysical markers of endothelial dysfunction in adults with hypopituitarism and severe GH deficiency
    • Elhadd T.A., Abdu T.A., Oxtoby J., Kennedy G., McLaren M., Neary R., et al. Biochemical and biophysical markers of endothelial dysfunction in adults with hypopituitarism and severe GH deficiency. J Clin Endocrinol Metab 86 (2001) 4223-4232
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 4223-4232
    • Elhadd, T.A.1    Abdu, T.A.2    Oxtoby, J.3    Kennedy, G.4    McLaren, M.5    Neary, R.6
  • 6
    • 33646865444 scopus 로고    scopus 로고
    • Peripheral fibrinolytic markers, soluble adhesion molecules, inflammatory cytokines and endothelial function in hypopituitary adults with growth hormone deficiency
    • Gómez J.M., Sahún M., Vila R., Domènech P., Catalina P., Soler J., et al. Peripheral fibrinolytic markers, soluble adhesion molecules, inflammatory cytokines and endothelial function in hypopituitary adults with growth hormone deficiency. Clin Endocrinol (Oxf) 64 (2006) 632-639
    • (2006) Clin Endocrinol (Oxf) , vol.64 , pp. 632-639
    • Gómez, J.M.1    Sahún, M.2    Vila, R.3    Domènech, P.4    Catalina, P.5    Soler, J.6
  • 7
    • 0023185776 scopus 로고
    • Plasminogen activator inhibitor in plasma: risk factor for recurrent myocardial infarction
    • Hamsten A., De Faire U., Walldius G., Dahlen G., Szamosi A., Landou C., et al. Plasminogen activator inhibitor in plasma: risk factor for recurrent myocardial infarction. Lancet 2 (1987) 3-9
    • (1987) Lancet , vol.2 , pp. 3-9
    • Hamsten, A.1    De Faire, U.2    Walldius, G.3    Dahlen, G.4    Szamosi, A.5    Landou, C.6
  • 8
    • 2442429603 scopus 로고    scopus 로고
    • Tumor necrosis factor alpha activates the human plasminogen activator inhibitor-1 gene through a distal nuclear factor kappaB site
    • Hou B., Eren M., Painter C.A., Covington J.W., Dixon J.D., Schoenhard J.A., et al. Tumor necrosis factor alpha activates the human plasminogen activator inhibitor-1 gene through a distal nuclear factor kappaB site. J Biol Chem 279 (2004) 18127-18136
    • (2004) J Biol Chem , vol.279 , pp. 18127-18136
    • Hou, B.1    Eren, M.2    Painter, C.A.3    Covington, J.W.4    Dixon, J.D.5    Schoenhard, J.A.6
  • 9
    • 0035169759 scopus 로고    scopus 로고
    • Plasminogen activator inhibitor type-1 (part one): basic mechanisms, regulation, and role for thromboembolic disease
    • Huber K. Plasminogen activator inhibitor type-1 (part one): basic mechanisms, regulation, and role for thromboembolic disease. J Thromb Haemostasis 11 (2001) 183-193
    • (2001) J Thromb Haemostasis , vol.11 , pp. 183-193
    • Huber, K.1
  • 10
    • 0029808713 scopus 로고    scopus 로고
    • Long-term treatment with growth hormone decreases plasminogen activator inhibitor-1 and tissue plasminogen activator in growth hormone-deficient adults
    • Johansson J.O., Landin K., Johannsson G., Tengborn L., and Bengtsson B.A. Long-term treatment with growth hormone decreases plasminogen activator inhibitor-1 and tissue plasminogen activator in growth hormone-deficient adults. Thromb Haemostasis 76 (1996) 422-428
    • (1996) Thromb Haemostasis , vol.76 , pp. 422-428
    • Johansson, J.O.1    Landin, K.2    Johannsson, G.3    Tengborn, L.4    Bengtsson, B.A.5
  • 11
    • 0027360661 scopus 로고
    • Predictive value of tissue plasminogen activator mass concentration on long-term mortality in patients with coronary heart disease
    • Jansonn J.H., Olofsson B.O., and Nilsson T.K. Predictive value of tissue plasminogen activator mass concentration on long-term mortality in patients with coronary heart disease. Circulation 88 (1993) 2030-2034
    • (1993) Circulation , vol.88 , pp. 2030-2034
    • Jansonn, J.H.1    Olofsson, B.O.2    Nilsson, T.K.3
  • 12
    • 0028258062 scopus 로고
    • High fibrinogen and plasminogen activator inhibitor activity in growth hormone-deficient adults
    • Johansson J.O., Landin K., Tengborn L., Rosén T., and Bengtsson B.A. High fibrinogen and plasminogen activator inhibitor activity in growth hormone-deficient adults. Arterioscler Thromb 14 (1994) 434-437
    • (1994) Arterioscler Thromb , vol.14 , pp. 434-437
    • Johansson, J.O.1    Landin, K.2    Tengborn, L.3    Rosén, T.4    Bengtsson, B.A.5
  • 13
    • 18344381771 scopus 로고    scopus 로고
    • Short-term safety and efficacy of human GH replacement therapy in 595 adults with GH deficiency: a comparison of two dosage algorithms
    • Kehely A., Bates P.C., Frewer P., Birkett M., Blum W.F., Mamessier P., et al. Short-term safety and efficacy of human GH replacement therapy in 595 adults with GH deficiency: a comparison of two dosage algorithms. J Clin Endocrinol Metab 87 (2002) 1974-1979
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 1974-1979
    • Kehely, A.1    Bates, P.C.2    Frewer, P.3    Birkett, M.4    Blum, W.F.5    Mamessier, P.6
  • 14
    • 33745431433 scopus 로고    scopus 로고
    • Plasminogen activator inhibitor-1 expression and secretion are stimulated by growth hormone and interleukin-6 in 3T3-L1 adipocytes
    • Kralisch S., Klein J., Lossner U., Blu{double acute}her M., Paschke R., Stumvoll M., et al. Plasminogen activator inhibitor-1 expression and secretion are stimulated by growth hormone and interleukin-6 in 3T3-L1 adipocytes. Mol Cell Endocrinol 253 (2006) 56-62
    • (2006) Mol Cell Endocrinol , vol.253 , pp. 56-62
    • Kralisch, S.1    Klein, J.2    Lossner, U.3    Bluher, M.4    Paschke, R.5    Stumvoll, M.6
  • 15
    • 0034082939 scopus 로고    scopus 로고
    • Increase of adhesion molecules, fibrinogen, type-1 plasminogen activator inhibitor and orosomucoid in growth hormone (GH) deficient adults and their modulation by recombinant human GH replacement
    • Kvasnicka J., Marek J., Kvasnicka T., Weiss V., Marková M., Stěpán J., et al. Increase of adhesion molecules, fibrinogen, type-1 plasminogen activator inhibitor and orosomucoid in growth hormone (GH) deficient adults and their modulation by recombinant human GH replacement. Clin Endocrinol (Oxf) 52 (2000) 543-548
    • (2000) Clin Endocrinol (Oxf) , vol.52 , pp. 543-548
    • Kvasnicka, J.1    Marek, J.2    Kvasnicka, T.3    Weiss, V.4    Marková, M.5    Stěpán, J.6
  • 16
    • 0031979233 scopus 로고    scopus 로고
    • PAI plasma levels in a general population without clinical evidence of atherosclerosis. Relation to environmental and genetic determinants
    • Margaglione M., Cappucci G., d'Addedda M., Colaizzo D., Giuliani N., Vecchione G., et al. PAI plasma levels in a general population without clinical evidence of atherosclerosis. Relation to environmental and genetic determinants. Arterioscler Thromb Vasc Biol 18 (1998) 562-567
    • (1998) Arterioscler Thromb Vasc Biol , vol.18 , pp. 562-567
    • Margaglione, M.1    Cappucci, G.2    d'Addedda, M.3    Colaizzo, D.4    Giuliani, N.5    Vecchione, G.6
  • 17
    • 0031455723 scopus 로고    scopus 로고
    • Plasminogen activator inhibitor-1 (PAI-1) antigen plasma levels in subjects attending a metabolic ward. Relation to polymorphism of PAI-1 and angiotensin-converting enzime (ACE) genes
    • Margaglione M., Grandone E., Vecchione G., Cappucci G., Giuliani N., Colaizzo D., et al. Plasminogen activator inhibitor-1 (PAI-1) antigen plasma levels in subjects attending a metabolic ward. Relation to polymorphism of PAI-1 and angiotensin-converting enzime (ACE) genes. Arterioscler Thromb Vasc Biol 17 (1997) 2082-2087
    • (1997) Arterioscler Thromb Vasc Biol , vol.17 , pp. 2082-2087
    • Margaglione, M.1    Grandone, E.2    Vecchione, G.3    Cappucci, G.4    Giuliani, N.5    Colaizzo, D.6
  • 18
    • 0027441963 scopus 로고
    • Fibrinolytic activity, clotting factors and long-term incidence of ischaemic heart disease in the Northwick Park Heart Study
    • Meade T.W., Ruddock V., Stirling Y., Chakrabarti R., and Miller G.J. Fibrinolytic activity, clotting factors and long-term incidence of ischaemic heart disease in the Northwick Park Heart Study. Lancet 342 (1993) 1076-1079
    • (1993) Lancet , vol.342 , pp. 1076-1079
    • Meade, T.W.1    Ruddock, V.2    Stirling, Y.3    Chakrabarti, R.4    Miller, G.J.5
  • 19
    • 0027267328 scopus 로고
    • Stimulation of plasminogen activator inhibitor in vivo by infusion of angiotensin II. evidence of a potential interaction between the renin-angiotensin system and fibrinolytic function
    • Ridker P.M., Gaboury C.L., Conlin P.R., Seely E.W., Williams G.H., and Vaughan D.E. Stimulation of plasminogen activator inhibitor in vivo by infusion of angiotensin II. evidence of a potential interaction between the renin-angiotensin system and fibrinolytic function. Circulation 87 (1993) 1969-1973
    • (1993) Circulation , vol.87 , pp. 1969-1973
    • Ridker, P.M.1    Gaboury, C.L.2    Conlin, P.R.3    Seely, E.W.4    Williams, G.H.5    Vaughan, D.E.6
  • 20
    • 0027274074 scopus 로고
    • Endogenous tissue-type plasminogen activator and risk of myocardial infarction
    • Ridker P.M., Vaughan D.E., Stampfer M.J., Manson J.E., and Hennekens C.H. Endogenous tissue-type plasminogen activator and risk of myocardial infarction. Lancet 341 (1993) 1165-1168
    • (1993) Lancet , vol.341 , pp. 1165-1168
    • Ridker, P.M.1    Vaughan, D.E.2    Stampfer, M.J.3    Manson, J.E.4    Hennekens, C.H.5
  • 21
    • 0028226514 scopus 로고
    • Prospective study of endogenous tissue plasminogen activator and risk of stroke
    • Ridker P.M., Hennekens C.H., Stampfer M.J., Manson J., and Vaughan D.E. Prospective study of endogenous tissue plasminogen activator and risk of stroke. Lancet 343 (1994) 940-943
    • (1994) Lancet , vol.343 , pp. 940-943
    • Ridker, P.M.1    Hennekens, C.H.2    Stampfer, M.J.3    Manson, J.4    Vaughan, D.E.5
  • 22
    • 0025333249 scopus 로고
    • Premature mortality due to cardiovascular disease in hypopituitarism
    • Rosén T., and Bengtsson B.A. Premature mortality due to cardiovascular disease in hypopituitarism. Lancet 336 (1990) 285-288
    • (1990) Lancet , vol.336 , pp. 285-288
    • Rosén, T.1    Bengtsson, B.A.2
  • 23
    • 0033780719 scopus 로고    scopus 로고
    • Alterations of haemostatic and fibrinolytic markers in adult patients with growth hormone deficiency and with acromegaly
    • Sartorio A., Cattaneo M., Bucciarelli P., Bottasso B., Porretti S., Epaminonda P., et al. Alterations of haemostatic and fibrinolytic markers in adult patients with growth hormone deficiency and with acromegaly. Exp Clin Endocrinol Diabetes 108 (2000) 486-492
    • (2000) Exp Clin Endocrinol Diabetes , vol.108 , pp. 486-492
    • Sartorio, A.1    Cattaneo, M.2    Bucciarelli, P.3    Bottasso, B.4    Porretti, S.5    Epaminonda, P.6
  • 24
    • 0036227606 scopus 로고    scopus 로고
    • Effects of GH replacement on endothelial function and large-artery stiffness in GH-deficient adults: a randomized, double-blind, placebo-controlled study
    • Smith J.C., Evans L.M., Wilkinson I., Goodfellow J., Cockcroft J.R., Scanlon M.F., et al. Effects of GH replacement on endothelial function and large-artery stiffness in GH-deficient adults: a randomized, double-blind, placebo-controlled study. Clin Endocrinol (Oxf) 56 (2002) 493-501
    • (2002) Clin Endocrinol (Oxf) , vol.56 , pp. 493-501
    • Smith, J.C.1    Evans, L.M.2    Wilkinson, I.3    Goodfellow, J.4    Cockcroft, J.R.5    Scanlon, M.F.6
  • 25
    • 0035835469 scopus 로고    scopus 로고
    • Association between premature mortality and hypopituitarism. West Midlands Prospective Hypopituitary Study Group
    • Tomlinson J.W., Holden N., Hills R.K., Wheatley K., Clayton R.N., Bates A.S., et al. Association between premature mortality and hypopituitarism. West Midlands Prospective Hypopituitary Study Group. Lancet 357 9254 (2001) 425-431
    • (2001) Lancet , vol.357 , Issue.9254 , pp. 425-431
    • Tomlinson, J.W.1    Holden, N.2    Hills, R.K.3    Wheatley, K.4    Clayton, R.N.5    Bates, A.S.6
  • 26
    • 0028912882 scopus 로고
    • Angiotensin II regulates the expression of plasminogen activator inhibitor-1 in cultured endothelial cells. A potential link between the rennin-angiotensin system and thrombosis
    • Vaughan D.E., Lazos S.A., and Tong K. Angiotensin II regulates the expression of plasminogen activator inhibitor-1 in cultured endothelial cells. A potential link between the rennin-angiotensin system and thrombosis. J Clin Investig 95 (1995) 995-1001
    • (1995) J Clin Investig , vol.95 , pp. 995-1001
    • Vaughan, D.E.1    Lazos, S.A.2    Tong, K.3
  • 27
    • 0043166537 scopus 로고    scopus 로고
    • Plasminogen activator inhibitor-1 and the calculus of mortality after myocardial infarction
    • Vaughan D.E. Plasminogen activator inhibitor-1 and the calculus of mortality after myocardial infarction. Circulation 108 (2003) 376-377
    • (2003) Circulation , vol.108 , pp. 376-377
    • Vaughan, D.E.1
  • 28
    • 0028836576 scopus 로고
    • The effect of low dose recombinant human growth hormone replacement on regional fat distribution, insulin sensitivity, and cardiovascular risk factors in hypopituitary adults
    • Weaver J.U., Monson J.P., Noonan K., John W.G., Edwards A., Evans K.A., et al. The effect of low dose recombinant human growth hormone replacement on regional fat distribution, insulin sensitivity, and cardiovascular risk factors in hypopituitary adults. J Clin Endocrinol Metab 80 (1995) 153-159
    • (1995) J Clin Endocrinol Metab , vol.80 , pp. 153-159
    • Weaver, J.U.1    Monson, J.P.2    Noonan, K.3    John, W.G.4    Edwards, A.5    Evans, K.A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.