Spared and impaired abilities in community-dwelling patients entering the severe stage of alzheimer's disease

Dementia and Geriatric Cognitive Disorders

Volumn 28, Issue 5, 2009, Pages 427-432

  Gillioz, Anne Sophie ^a   Villars, Hélène ^b   Voisin, Thierry ^b,c   Cortes, Frédéric ^c   Gillette Guyonnet, Sophie ^b,c   Andrieu, Sandrine ^b,c   Gardette, Virginie ^b,c   Nourhashémi, Fati ^b,c   Ousset, Pierre Jean ^b,c   Jouanny, Pierre ^a   Vellas, Bruno ^b,c  

^a RENNES UNIVERSITY HOSPITAL   (France)

^b TOULOUSE UNIVERSITY HOSPITAL   (France)

^c UNIVERSITÉ PAUL SABATIER   (France)

Author keywords

[No Author keywords available]

Indexed keywords

AGED; AGITATION; ALZHEIMER DISEASE; APATHY; APTITUDE; ARTICLE; BEHAVIOR; BEHAVIOR DISORDER; CAREGIVER BURDEN; CLINICAL ASSESSMENT; COGNITION; COHORT ANALYSIS; CROSS-SECTIONAL STUDY; DAILY LIFE ACTIVITY; DETERIORATION; DISEASE SEVERITY; FEMALE; FOLLOW UP; FUNCTIONAL ASSESSMENT; GERIATRIC ASSESSMENT; HOME CARE; HUMAN; LANGUAGE; LOCOMOTION; LONGITUDINAL STUDY; MAJOR CLINICAL STUDY; MALE; MALNUTRITION; MEMORY; MINI MENTAL STATE EXAMINATION; NOMENCLATURE; NUTRITIONAL ASSESSMENT; PATIENT CARE; PERSONAL HYGIENE; PRIORITY JOURNAL; QUALITY OF LIFE; SOCIAL INTERACTION;

ACTIVITIES OF DAILY LIVING; AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; CAREGIVERS; CROSS-SECTIONAL STUDIES; FEMALE; GERIATRIC ASSESSMENT; HOUSING FOR THE ELDERLY; HUMANS; LANGUAGE; MALE; MALNUTRITION; MEMORY; NEUROPSYCHOLOGICAL TESTS; NUTRITION ASSESSMENT; ORIENTATION; QUALITY OF LIFE; RESIDENCE CHARACTERISTICS; RISK FACTORS; SEVERITY OF ILLNESS INDEX; SOCIAL BEHAVIOR;

EID: 70449516149     PISSN: 14208008     EISSN: None     Source Type: Journal    
DOI: 10.1159/000255635     Document Type: Article

References (30)

1. Auer SR, Sclan SG, Yaffee RA, Reisberg B: The neglected half of Alzheimer disease: Cognitive and functional concomitants of severe dementia. J Am Geriatr Soc 1994; 42: 1266-1272.
2. Boller F, Verny M, Hugonot-Diener L, Saxton J: Clinical features and assessment of severe dementia. A review. Eur J Neurol 2002; 9: 125-136.
3. Tariot PN: Medical management of advanced dementia. J Am Geriatr Soc 2003; 51(5 Suppl Dementia):S305-S313.
4. Ramaroson H, Helmer C, Barberger-Gateau P, PAQUID: Prevalence of dementia and Alzheimer's disease among subjects aged 75 years or over: Updated results of the PAQUID cohort (in French). Rev Neurol (Paris) 2003; 159: 405-411.
5. Vellas B, Gauthier S, Allain H, Andrieu S, Aquino JP, Berrut G, Berthel M, Blanchard F, Camus V, Dartigues JF, Dubois B, Forette F, Franco A, Gonthier R, Grand A, Hervy MP, Jeandel C, Joel ME, Jouanny P, Lebert F, Michot P, Montastruc JL, Nourhashemi F, Ousset PJ, Pariente J, Rigaud AS, Robert P, Ruault G, Strubel D, Touchon J, Verny M, Vetel JM: Consensus statement on dementia of Alzheimer type in the severe stage. J Nutr Health Aging 2005; 9: 330-338. (Pubitemid 41499862)
6. Bullock R, Hammond G: The management of severe Alzheimer disease. Alzheimer Dis Assoc Disord 2003; 17(suppl 3):S80-S85.
7. Gillette-Guyonnet S, Nourhashemi F, Andrieu S, Cantet C, Micas M, Ousset PJ, Vellas B, the REAL.FR group: The REAL.FR research program on Alzheimer's disease and its management: Methods and preliminary results. J Nutr Health Aging 2003; 7: 91-96.
8. Folstein MF, Folstein SE, McHugh PR: 'Mini-Mental-State'. A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res 1975; 12: 189-198.
9. Saxton J, McGonigle-Gibson KL, Swihart AA, Miller M, Boller F: Assessment of the severely impaired patient: Description and validation of a new neuropsychological test battery. Psychol Assess 1990; 2: 298-303.
10. Katz S, Akpom CA: Index of ADL. Med Care 1976; 14: 116-118.
11. Lawton MP, Brody EM: Assessment of older people: Self-maintaining and instrumental activities of daily living. Gerontologist 1969; 9: 179-186.
12. Cummings JL: The Neuropsychiatric Inventory: Assessing psychopathology in dementia patients. Neurology 1997; 48(suppl 6):10S-16S.
13. Vellas B, Guigoz Y, Garry PJ, Nourhashemi F, Bennahum D, Lauque S, Albarede JL: The Mini Nutritional Assessment (MNA) and its use in grading the nutritional state of elderly patients. Nutrition 1999; 15: 116-122.
14. Zarit SH, Reever KE, Bach-Peterson I: Relatives of the impaired elderly: Correlates of feelings of burden. Gerontologist 1980; 20: 649-655.
15. Benoit M, Robert PH, Staccini P, Brocker P, Guerin O, Lechowski L, Vellas B; REAL.FR Group: One-year longitudinal evaluation of neuropsychiatric symptoms in Alzheimer's disease. The REAL.FR Study. J Nutr Health Aging 2005; 9: 95-99. (Pubitemid 40478065)
16. Panisset M, Roudier M, Saxton J, Boller F: Severe Impairment Battery. A neuropsychological test for severly demented patients. Arch Neurol 1994; 51: 41-45.
17. Feldman H, Gauthier S, Hecker J, Vellas B, Xu Y, Ieni JR, Scwam EM; Donepezil MSAD Study Investigators Group: Efficacy and safety of donepezil in patients with more severe Alzheimer's disease: A subgroup analysis from a randomized, placebo-controlled trial. Int J Geriatr Psychiatry 2005; 20: 559-569.
18. Black SE, Doody R, Li H, McRae T, Jambor KM, Xu Y, Sun Y, Perdomo CA, Richardson S: Donepezil preserves cognition and global function in patients with severe Alzheimer disease. Neurology 2007; 69: 459-469.
19. Winblad B, Kilander L, Eriksson S, Minthon L, Batsman S, Wetterholm AL, Jansson-Blixt C, Haglund A; Severe Alzheimer's Disease Study Group: Donepezil in patients with severe Alzheimer's disease: Double-blind, parallel-group, placebo-controlled study. Lancet 2006; 367: 1057-1065.
20. Winblad B, Poritis N: Memantine in severe dementia: Results of the 9M-Best Study (Benefit and efficacy in severely demented patients during treatment with memantine). Int J Geriatr Psychiatry 1999; 14: 135-146.
21. Suh GH, Ju YS, Yeon BK, Shah A: A longitudinal study of Alzheimer's disease: Rates of cognitive and functional decline. Int J Geriatr Psychiatry 2004; 19: 817-824.
22. Carpenter GI, Hastie CL, Morris JN, Fries BE, Ankri J: Measuring change in activities of daily living in nursing home residents with moderate to severe cognitive impairement. BMC Geriatr 2006; 6: 7.
23. Mega MS, Cummings JL, Fiorello T, Gornbein J: The spectrum of behavioral changes in Alzheimer's disease. Neurology 1996; 46: 130-135.
24. Benoit M, Staccini P, Brocker P, Benhamidat T, Bertogliati C, Lechowski L, Tortrat D, Robert PH: Behavioral and psychologic symptoms in Alzheimer's disease: Results of the REAL.FR study (in French). Rev Med Int 2003: 319-324.
25. Hart DJ, Craig D, Compton SA, Critchlow S, Kerrigan BM, McIlroy SP, Passmore P: A retrospective study of the behavioural and psychological symptoms of mid and late phase Alzheimer's disease. Int J Geriatr Psychiatry 2003; 18: 1037-1042.
26. Lopez OL, Becker JT, Sweet RA, Klunk W, Kaufer DI, Saxton J, Habeych M, DeKosky ST: Psychiatric symptoms vary with the severity of dementia in probable Alzheimer's disease. J Neuropsychiatry Clin Neurosci 2003; 15: 346-353.
27. Vellas B, Lauque S, Gillette-Guyonnet S, Andrieu S, Cortes F, Nourhashemi F, Cantet C, Ousset PJ, Grandjean H; The REAL.FR Group: Impact of nutritional status on the evolution of Alzheimer's disease and on response to acetylcholinesterase inhibitor treatment. J Nutr Health Aging 2005; 9: 75-80.
28. Lauque S, Arnaud-Battandier F, Gillette S, Plaze JM, Andrieu S, Cantet C, Vellas B: Improvement of weight and fat-free mass with oral nutritional supplementation in patients with Alzheimer's disease at risk of malnutrition: A prospective randomized study. J Am Geriatr Soc 2004; 52: 1702-1707.
29. Gort AM, Mingot M, Gomez X, Soler T, Torres G, Sacristàn O, Miguelsanz S, Nicolas F, Perez A, de Miguel M, Cabau J: Use of the Zarit scale for assessing caregiver burden and collapse in caregiving at home in dementias. Int J Geriatr Psychiatry 2007; 22: 957-962.
30. Coen RF, Swanwick GR, O'Boyle CA, Coakley D: Behaviour disturbance and other predictors of carer burden in Alzheimer's disease. Int J Geriatr Psychiatry 1997; 12: 331-336.