Phenotypic and genotypic data integration and exploration through a web-service architecture

BMC Bioinformatics

Volumn 10, Issue SUPPL. 12, 2009, Pages

  Nuzzo, Angelo ^a   Riva, Alberto ^b   Bellazzi, Riccardo ^a  

^a UNIVERSITY OF PAVIA   (Italy)

^b UNIVERSITY OF FLORIDA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DATA INTEGRATION; KNOWLEDGE MANAGEMENT; WEB SERVICES;

BIOMEDICAL INFORMATICS; HYPOTHESIS GENERATION; INFORMATION TECHNOLOGY INFRASTRUCTURE; KNOWLEDGE MANAGEMENT TOOL; PHENOTYPIC DATA; SOFTWARE SYSTEMS; SYSTEM FUNCTIONALITY; WEB SERVICE ARCHITECTURE;

INFORMATION MANAGEMENT;

ARTICLE; AUTOMATION; BIOINFORMATICS; COMPUTER INTERFACE; DATA ANALYSIS SOFTWARE; EQUIPMENT DESIGN; GENETIC ASSOCIATION; GENOTYPE; INFORMATION PROCESSING; INFORMATION RETRIEVAL; INFORMATION SERVICE; PHENOTYPE; SINGLE NUCLEOTIDE POLYMORPHISM;

EID: 70449504225     PISSN: None     EISSN: 14712105     Source Type: Journal    
DOI: 10.1186/1471-2105-10-S12-S5     Document Type: Article

References (15)

1. Botstein D, Risch N. Discovering genotypes underlying human phenotypes: past successes for mendelian disease, future approaches for complex disease. Nature Genetics 2003, 33:228-237. 10.1038/ng1090, 12610532.
2. Martin-Sanchez F, Iakovidis I, Norager S, Maojo V, de Groen P, Lei J, Jones T, Abraham-Fuchs K, Apweiler R. Synergy between medical informatics and bioinformatics: facilitating genomic medicine for future health care. J Biomed Inform 2004, 37:30-42. 10.1016/j.jbi.2003.09.003, 15016384.
3. Nuzzo A, Segagni D, Milani G, Rognoni C, Bellazzi R. A dynamic query system for supporting phenotype mining in genetic studies. Stud Health Technol Inform 2007, 129(Pt 2):1275-1279.
4. Kinball R, Ross M. The data warehouse toolkit 2002, Wiley and Sons, second.
5. Wyderka KC. Data warehouse technique for outcomes management. Health Management Technology 1999, 20:16-17.
6. Pentaho Analysis Service The Mondrian OLAP Project , http://mondrian.pentaho.org
7. Agarwala R, Biesecker LG, Hopkins KA, Francomano CA, Schaffer AA. Software for constructing and verifying pedigrees within large genealogies and an application to the old order amish of lancaster county. Genome Res 1998, 8:211-221.
8. Sala C, Bione S, Crocco L, Gatti M, Poggiali E, Bellazzi R, Buetti I, Rognoni C, Camaschella C, Toniolo D. The val borbera project: epidemiological and genealogical analysis of an isolated population in northern Italy. Proceedings of the European Society of Human Genetics Conference 2006,
9. W3C Working Group. , http://www.w3.org/TR/soap/
10. W3C Working Group. Note 11 February 2004. WebServices Glossary , http://www.w3.org/TR/ws-gloss/
11. Nuzzo A, Riva A. A knowledge management tool for translational research. Proceedings of the 1st AMIA Summit on Translational Bioinformatics 2008, 171.
12. Online Mendelian Inheritance in Man, OMIM (TM) McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University (Baltimore, MD) and National Center for Biotechnology Information, National Library of Medicine (Bethesda, MD). , http://www.ncbi.nlm.nih.gov/omim/
13. Becker KG, Barnes KC, Bright TJ, Wang SA. The genetic association database. Nat Genet 2004, 36(5):431-432. 10.1038/ng0504-431, 15118671.
14. Balding DJ. A tutorial on statistical methods for population association studies. Nat Rev Genet 2006, 7(10):781-791. 10.1038/nrg1916, 16983374.
15. Cordell JC, Clayton DG. Genetic association studies. Lancet 2005, 366(9491):1121-1131. 10.1016/S0140-6736(05)67424-7, 16182901.