-
1
-
-
2342667387
-
The development of proteasome inhibitors as anticancer drugs
-
DOI 10.1016/S1535-6108(04)00120-5, PII S1535610804001205
-
Adams J. The development of proteasome inhibitors as anticancer drugs. Cancer Cell. 2004;5:417-421. (Pubitemid 38610244)
-
(2004)
Cancer Cell
, vol.5
, Issue.5
, pp. 417-421
-
-
Adams, J.1
-
2
-
-
0037973279
-
A phase 2 study of Bortezomib in relapsed, refractory myeloma
-
DOI 10.1056/NEJMoa030288
-
Richardson PG, Barlogie B, Berenson J, et al. A phase 2 study of bortezomib in relapsed, refractory myeloma. N Engl J Med. 2003;348:2609-2617. (Pubitemid 36741588)
-
(2003)
New England Journal of Medicine
, vol.348
, Issue.26
, pp. 2609-2617
-
-
Richardson, P.G.1
Barlogie, B.2
Berenson, J.3
Singhal, S.4
Jagannath, S.5
Irwin, D.6
Rajkumar, S.V.7
Srkalovic, G.8
Alsina, M.9
Alexanian, R.10
Siegel, D.11
Orlowski, R.Z.12
Kuter, D.13
Limentani, S.A.14
Lee, S.15
Hideshima, T.16
Esseltine, D.-L.17
Kauffman, M.18
Adams, J.19
Schenkein, D.P.20
Anderson, K.C.21
more..
-
3
-
-
0036020941
-
NF-kappaB as a therapeutic target in cancer
-
Orlowski RZ, Baldwin AS Jr. NF-kappaB as a therapeutic target in cancer. Trends Mol Med. 2002;8:385-389.
-
(2002)
Trends Mol Med
, vol.8
, pp. 385-389
-
-
Orlowski, R.Z.1
Baldwin Jr., A.S.2
-
4
-
-
0033177897
-
NF-kappa B and chemoresistance: Potentiation of cancer drugs via inhibition of NF-kappa B
-
Cusack JC, Liu R, Baldwin AS. NF-kappa B and chemoresistance: potentiation of cancer drugs via inhibition of NF-kappa B. Drug Resist Updat. 1999;2:271-273.
-
(1999)
Drug Resist Updat
, vol.2
, pp. 271-273
-
-
Cusack, J.C.1
Liu, R.2
Baldwin, A.S.3
-
5
-
-
34547660308
-
Promiscuous Mutations Activate the Noncanonical NF-κB Pathway in Multiple Myeloma
-
DOI 10.1016/j.ccr.2007.07.003, PII S1535610807002024
-
Keats JJ, Fonseca R, Chesi M, et al. Promiscuous mutations activate the noncanonical NF-kappaB pathway in multiple myeloma. Cancer Cell. 2007;12:131-144. (Pubitemid 47208626)
-
(2007)
Cancer Cell
, vol.12
, Issue.2
, pp. 131-144
-
-
Keats, J.J.1
Fonseca, R.2
Chesi, M.3
Schop, R.4
Baker, A.5
Chng, W.-J.6
Van Wier, S.7
Tiedemann, R.8
Shi, C.-X.9
Sebag, M.10
Braggio, E.11
Henry, T.12
Zhu, Y.-X.13
Fogle, H.14
Price-Troska, T.15
Ahmann, G.16
Mancini, C.17
Brents, L.A.18
Kumar, S.19
Greipp, P.20
Dispenzieri, A.21
Bryant, B.22
Mulligan, G.23
Bruhn, L.24
Barrett, M.25
Valdez, R.26
Trent, J.27
Stewart, A.K.28
Carpten, J.29
Bergsagel, P.L.30
more..
-
6
-
-
18544367201
-
NF-κB as a therapeutic target in multiple myeloma
-
DOI 10.1074/jbc.M200360200
-
Hideshima T, Chauhan D, Richardson P, et al. NF-kappa B as a therapeutic target in multiple myeloma. J Biol Chem. 2002;277:16639-16647. (Pubitemid 34967682)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.19
, pp. 16639-16647
-
-
Hideshima, T.1
Chauhan, D.2
Richardson, P.3
Mitsiades, C.4
Mitsiades, N.5
Hayashi, T.6
Munshi, N.7
Dang, L.8
Castro, A.9
Palombella, V.10
Adams, J.11
Anderson, K.C.12
-
7
-
-
70349243697
-
Bortezomib induces canonical nuclear factor-κB activation in multiple myeloma cells
-
Hideshima T, Ikeda H, Chauhan D, et al. Bortezomib induces canonical nuclear factor-κB activation in multiple myeloma cells. Blood. 2009;114:1046-1052.
-
(2009)
Blood
, vol.114
, pp. 1046-1052
-
-
Hideshima, T.1
Ikeda, H.2
Chauhan, D.3
-
8
-
-
20844435806
-
Small-molecule inhibition of proteasome and aggresome function induces synergistic antitumor activity in multiple myeloma
-
DOI 10.1073/pnas.0503221102
-
Hideshima T, Bradner JE, Wong J, et al. Small-molecule inhibition of proteasome and aggresome function induces synergistic antitumor activity in multiple myeloma. Proc Natl Acad Sci U S A. 2005;102:8567-8572. (Pubitemid 40862776)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.24
, pp. 8567-8572
-
-
Hideshima, T.1
Bradner, J.E.2
Wong, J.3
Chauhan, D.4
Richardson, P.5
Schreiber, S.L.6
Anderson, K.C.7
-
9
-
-
53049110009
-
Myc regulates aggresome formation, the induction of Noxa, and apoptosis in response to the combination of bortezomib and SAHA
-
Nawrocki ST, Carew JS, Maclean KH, et al. Myc regulates aggresome formation, the induction of Noxa, and apoptosis in response to the combination of bortezomib and SAHA. Blood. 2008;112:2917-2926.
-
(2008)
Blood
, vol.112
, pp. 2917-2926
-
-
Nawrocki, S.T.1
Carew, J.S.2
Maclean, K.H.3
-
10
-
-
34547807613
-
Global changes to the ubiquitin system in Huntington's disease
-
DOI 10.1038/nature06022, PII NATURE06022
-
Bennett EJ, Shaler TA, Woodman B, et al. Global changes to the ubiquitin system in Huntington's disease. Nature. 2007;448:704-708. (Pubitemid 47236860)
-
(2007)
Nature
, vol.448
, Issue.7154
, pp. 704-708
-
-
Bennett, E.J.1
Shaler, T.A.2
Woodman, B.3
Ryu, K.-Y.4
Zaitseva, T.S.5
Becker, C.H.6
Bates, G.P.7
Schulman, H.8
Kopito, R.R.9
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