Implementation of an automated on-line high-performance liquid chromatography monitoring system for 'cycle to cycle' control of simulated moving beds

Journal of Chromatography A

Volumn 1216, Issue 50, 2009, Pages 8806-8815

  Langel, Christian ^a   Grossmann, Cristian ^a   Morbidelli, Massimo ^a   Morari, Manfred ^a   Mazzotti, Marco ^a  

^a ETH ZURICH   (Switzerland)

Author keywords

Automated on line HPLC monitoring system; Chiral chromatography; Repetitive model predictive control (RMPC); Simulated moving bed chromatography

Indexed keywords

AUTOMATED ON-LINE HPLC MONITORING SYSTEM; CHIRAL CHROMATOGRAPHY; CHIRALCEL OD; CHROMATOGRAPHIC CONDITIONS; CONCENTRATION OF; FEED BACK INFORMATION; FINE CHEMICALS; GUAIFENESIN; MOBILE PHASE; MONITORING SYSTEM; ON-LINE MONITORING SYSTEM; OPERATION CONDITIONS; OPTICAL DETECTORS; PRODUCT SPECIFICATIONS; PRODUCT STREAMS; REPETITIVE MODEL PREDICTIVE CONTROL (RMPC); SIMULATED MOVING BED; SIMULATED MOVING BED CHROMATOGRAPHY; SIMULATED MOVING BEDS; SOLVENT CONSUMPTION; TWO-PRODUCT; UV- AND;

AUTOMATION; CHIRALITY; CHROMATOGRAPHIC ANALYSIS; COLUMN CHROMATOGRAPHY; CONTROLLERS; ENANTIOMERS; ETHANOL; HIGH PRESSURE LIQUID CHROMATOGRAPHY; MODEL PREDICTIVE CONTROL; MONITORING; PREDICTIVE CONTROL SYSTEMS;

HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

ALCOHOL; GUAIFENESIN; SOLVENT;

ACCURACY; ARTICLE; AUTOANALYZER; AUTOMATION; CONCENTRATION (PARAMETERS); ENANTIOMER; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LINEAR SYSTEM; NONLINEAR SYSTEM; ONLINE MONITORING; POLARIMETER; PRIORITY JOURNAL; QUALITY CONTROL; RELIABILITY; SEPARATION TECHNIQUE; ULTRAVIOLET RADIATION;

AUTOMATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; ETHANOL; GUAIFENESIN; ONLINE SYSTEMS; RHEOLOGY; STEREOISOMERISM;

EID: 70449469157     PISSN: 00219673     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chroma.2009.02.005     Document Type: Article

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