Umbilical cord blood and type 1 diabetes: A road ahead or dead end?

Diabetes Care

Volumn 32, Issue 11, 2009, Pages 2138-2139

  Bleich, David ^a  

^a RUTGERS NEW JERSEY MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD TRANSFUSION; CD4+ CD25+ T LYMPHOCYTE; CORD BLOOD STEM CELL TRANSPLANTATION; EDITORIAL; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PANCREAS ISLET BETA CELL; TREATMENT FAILURE; UMBILICAL CORD BLOOD;

ANIMALS; BLOOD BANKS; BLOOD TRANSFUSION; CHILD, PRESCHOOL; CORD BLOOD STEM CELL TRANSPLANTATION; DIABETES MELLITUS, TYPE 1; FETAL BLOOD; HUMANS; INFANT; MICE; MICE, INBRED NOD; T-LYMPHOCYTES, REGULATORY;

EID: 70449434043     PISSN: 01495992     EISSN: 19355548     Source Type: Journal    
DOI: 10.2337/dc09-1456     Document Type: Editorial

References (4)

1. Haller MJ, Wasserfall CH, McGrail KM, Cintron M, Brusko TM, Wingard JR, Kelly SS, Shuster JJ, Atkinson MA, Schatz DA. Autologous umbilical cord blood transfusion in very young children with type 1 diabetes. Diabetes Care 2009;32:2041-2046
2. Zhao Y, Lin B, Darflinger R, Zhang Y, Holterman MJ, Skidgel RA. Human cord blood stem cell-modulated regulatory T lymphocytes reverse the autoimmune-caused type 1 diabetes in nonobese diabetic (NOD) mice. PLoS One 2009;4:e4226
3. Zhao Y, Wang H, Mazzone T. Identification of stem cells from human umbilical cord blood with embryonic and hematopoietic characteristics. Exp Cell Res 2006;312: 2454-2464 (Pubitemid 44036799)
4. Tang Q, Henriksen KJ, Bi M, Finger EB, Szot G, Ye J, Masteller EL, McDevitt H, Bonyhadi M, Bluestone JA. In vitro-expanded antigen-specific regulatory T cells suppress autoimmune diabetes. J Exp Med 2004;199:1455-1465