Ovotesticular disorder of sex development with a prostatic gland and review of literature

Andrologia

Volumn 41, Issue 6, 2009, Pages 387-391

  Irkilata, H C ^a   Basal, S ^a   Taslipinar, A ^a   Gur, A ^a   Piskin, M M ^a   Kurt, B ^a   Tahmaz, L ^a   Bolu, E ^a   Dayanc, M ^a  

^a GULHANE SCHOOL OF MEDICINE   (Turkey)

Author keywords

Hermaphroditism; Prostate; Sex differentiation disorder

Indexed keywords

TESTOSTERONE;

ADULT; ANDROGEN THERAPY; ARTICLE; AZOOSPERMIA; CASE REPORT; CHROMOSOME ANALYSIS; CYSTOSCOPY; DIGITAL RECTAL EXAMINATION; ENDOSCOPY; FEMALE GENITAL SYSTEM; GENITAL MALFORMATION; GYNECOMASTIA; HUMAN; HUMAN TISSUE; KARYOTYPE 46,XX; MALE; MICROSCOPY; NUCLEAR MAGNETIC RESONANCE IMAGING; ORCHIECTOMY; OVOTESTICULAR DISORDER; OVOTESTICULAR DISORDER OF SEX DEVELOPMENT; PHENOTYPE; PROSTATE; RARE DISEASE; SCROTAL PAIN; SEMEN ANALYSIS; SEXUAL DEVELOPMENT; TESTIS BIOPSY; XX MALE; Y CHROMOSOME;

EID: 70449394589     PISSN: 03034569     EISSN: 14390272     Source Type: Journal    
DOI: 10.1111/j.1439-0272.2009.00945.x     Document Type: Article

References (28)

1. Abusheikha N, Lass A, Brinsden P (2001) XX males without SRY gene and with infertility. Hum Reprod 16 : 717 718.
2. Alonso G, Pasqualini T, Busaniche J, Ruiz E, Chemes H (2007) True hermaphroditism in a phenotypic male without ambiguous genitalia: an unusual presentation at puberty. Horm Res 68 : 261 264.
3. Bansal N, Roy KS, Sharma DK, Sharma R (2005) Anatomical study on true hermaphroditism in an Indian pig (Sus scrofa domesticus). J Vet Sci 6 : 83 85.
4. Berger-Zaslav AL, Mehta L, Jacob J, Mercado T, Gadi I, Tepperberg JH, Palmer LS (2009) Ovotesticular disorder of sexual development (true hermaphroditism). Urology 73 : 293 296.
5. Berkovitz GD, Fechner PY, Marcantonio SM, Bland G, Stetten G, Goodfellow PN, Smith KD, Migeon CJ (1992) The role of the sex-determining region of the Y chromosome (SRY) in the etiology of 46XX true hermaphroditism. Hum Genet 88 : 411 416.
6. Boezio F, Brown CT, Ralph DJ (2005) True hermaphroditism presenting in adulthood as a scrotal mass. Urology 66 : 193.
7. Ceylan K, Algun E, Gunes M, Gonulalan H (2007) True hermaphroditism presenting as an inguinal hernia. Int Braz J Urol 33 : 72 73.
8. Consortium on the Management of Disorders of Sex Differentiation (2006) Clinical guidelines for the management of disorders of sex development in childhood. Rohnert Park, Intersex Society of North America.
9. Ghafoori M, Varedi P (2008) MRI in true hermaphroditism. Pediatr Radiol 38 : 814.
10. Houle AM, Taketo T (1992) True hermaphrodites: an experimental model in the mouse. J Urol 148 : 672 676.
11. Hughes IA, Houk C, Ahmed SF, Lee PA, Lawson Wilkins Pediatric Endocrine Society (LWPES)/European Society for Paediatric Endocrinology (ESPE) Consensus Group (2006) Consensus statement on management of intersex disorders. J Pediatr Urol 2 : 148 162. (Pubitemid 43840887)
12. Jaubert F, Nihoul-Fékété C, Lortat-Jacob S, Josso N, Fellous M (2004) Hermaphroditism pathology. Rom J Morphol Embryol 45 : 41 51.
13. Kanaka-Gantenbein CH, Papandreou E, Stefanaki K, Fryssira H, Kolialexi A, Sophocleous C, Mavron A, Kitsiou-Tzeli S, Chrousos GP (2007) Spontaneous ovulation in a true hermaphrodite with normal male phenotype and a rare 46,XX/47,XXY Klinefelter's mosaic karyotype. Horm Res 68 : 139 144.
14. Kropp BP, Keating MA, Moshang T, Duckett JW (1995) True hermaphroditism and normal male genitalia: an unusual presentation. Urology 46 : 736 739.
15. Ma S, Tang SS, HoYuen B, Bruyere H, Penaherrera M, Robinson WP (2003) Cytogenetic and molecular study of a premature male infant with 46,XX derived from ICSI: case report. Hum Reprod 18 : 2298 2301.
16. Malik V, Gupta D, Gill M, Salvi AL (2007) Seminoma in a male phenotype 46XX true hermaphrodite. Asian J Surg 30 : 85 87.
17. McDonough PG, Byrd JR, Tho PT, Otken L (1976) Gonadoblastoma in a true hermaphrodite with a 46,XX karyotype. Obstet Gynecol 47 : 355 358.
18. van Niekerk WA, Retief AE (1981) The gonads of human true hermaphrodites. Hum Genet 58 : 117 122.
19. Nieto K, Peña R, Palma I, Dorantes LM, Eraña L, Alvarez R, García-Cavazos R, Kofman-Alfaro S, Queipo G (2004) 45,X/47,XXX/47,XX, del(Y)(p?)/46,XX mosaicism causing true hermaphroditism. Am J Med Genet 130A : 311 314.
20. Nihoul-Fékété C, Thibaud E, Lortat-Jacob S, Josso N (2006) Long-term surgical results and patient satisfaction with male pseudohermaphroditism or true hermaphroditism: a cohort of 63 patients. J Urol 175 : 1878 1884.
21. Ouhilal S, Turco J, Nangia A, Stotland M, Manganiello PD (2005) True hermaphroditism presenting as bilateral gynecomastia in an adolescent phenotypic male. Fertil Steril 83 : 1041.
22. Prins GS, Putz O (2008) Molecular signaling pathways that regulate prostate gland development. Differentiation 76 : 641 659.
23. Ramsay M, Pfaffenzeller W, Kotze E, Bhengu L, Essop F, de Ravel T (2009) Chimerism in black southern African patients with true hermaphroditism 46,XX/47XY,+21 and 46,XX/46,XY. Ann N Y Acad Sci 1151 : 68 76.
24. Thompson AA (2008) Mesenchymal mechanism in prostate organogenesis. Differentiation 76 : 587 598.
25. Tomaselli S, Megiorni F, De Bernardo C, Elici A, Marrocco G, Maqquilli G, Grammatico B, Saccucci P, Valentini F, Mazzilli MC, Majore S, Grammatico P (2008) Syndromic true hermaphroditism due to an R-spondin1 (RSPO1) homozygous mutation. Hum Mutat 29 : 220 226.
26. Walker AM, Walker JL, Adams S, Shi E, McGlynn M, Verge CF (2000) True hermaphroditism. J Paediatr Child Health 36 : 69 73.
27. Wiersma R (2001) Management of the African child with true hermaphroditism. J Pediatr Surg 36 : 397 399.
28. Wiersma R (2004) True hermaphroditism in southern Africa: the clinical picture. Pediatr Surg Int 20 : 363 368.